Original title: Comparison of in vitro tests for measurement of estrogenity of chlorinated compounds and their use in the evaluation of biodegradation of chlorbenzoates by the fungus Panus tigrinus
Authors: Svobodová, Kateřina ; Covino, S. ; Křesinová, Zdena ; Cajthaml, Tomáš
Document type: Papers
Conference/Event: Odpadové fórum, Milovy (CZ), 2009-04-22 / 2009-04-24
Year: 2009
Language: eng
Abstract: Recently, contamination of the environment by endocrine disruptive compounds, toxicity of these chemicals and their biodegradability are widely studied. This work is focused on estrogenity of chlorinated phenols and chlorbenzoic acids that represent potential degradation products of PCB compounds. Two different yeast bioassays for evaluation of estrogenity based on recombinated strains of Saccharomyces cerevisie were compared in this work. Estrogenic activity of chlorbenzoic acids varied with the chemical structure of chemicals. A mixture of chlorbenzoates (initial concentration 10 ppm) was degraded by a ligninolytic fungus Panus tigrinus in liquid cultures. Chemicals resulting from degradation were tested for their estrogenity, however, results indicated that the test responses were inhibited probably by some compounds present in the fungal culture liquid
Keywords: biodegradation; chlorbenzoates; yeast assay
Project no.: CEZ:AV0Z50200510 (CEP), 2B06156 (CEP)
Funding provider: GA MŠk
Host item entry: Odpadové fórum 2009 - sborník přednášek, ISBN 978-80-02-02108-7

Institution: Institute of Microbiology AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0005744

Permalink: http://www.nusl.cz/ntk/nusl-41291


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Research > Institutes ASCR > Institute of Microbiology
Conference materials > Papers