Home > Conference materials > Papers > Hexahistidine-based tag for capillary electrophoresis-mass spektrometry analysis of oligosaccharides and N-linked glycans
Original title:
Hexahistidine-based tag for capillary electrophoresis-mass spektrometry analysis of oligosaccharides and N-linked glycans
Authors:
Partyka, Jan ; Křenková, Jana ; Čmelík, Richard ; Foret, František Document type: Papers Conference/Event: CECE 2018. International Interdisciplinary Meeting on Bioanalysis /15./, Brno (CZ), 20181015
Year:
2018
Language:
eng Abstract:
Various basic amino acids and peptides were studied as an alternative labels for capillary electrophoresis-mass spectrometry analysis of oligosaccharides. The hexahistidine-based label with big number of positive charges allowed to use effective and sensitive CE-MS analysis in positive ion mode both neutral and acidic glycans.
Keywords:
amino acids; CE-MS analysis; oligosaccharides; peptides Project no.: GJ16-09283Y (CEP), GBP206/12/G014 (CEP) Funding provider: GA ČR, GA ČR Host item entry: CECE 2018. 15th International Interdisciplinary Meeting on Bioanalysis, ISBN 978-80-904959-5-1