Original title: Synthesis of Steroid Derivatives for In Vitro Diagnostics.
Authors: Kos, Martin ; Váňa, Lubomír ; Žádný, Jaroslav ; Storch, Jan
Document type: Papers
Conference/Event: Advances in Organic, Bioorganic and Pharmaceutical Chemistry LIBLICE 2018 /53./, Lázně Bělohrad (CZ), 20181102
Year: 2018
Language: eng
Abstract: This work is focused on the synthesis of novel steroidal androgen derivatives consisting of a steroidal skeleton, a spacer and imidazole ring or a primary amine functional group. The starting material for the synthesis is represented by commercial available hydroxy-androgens, which are further modified. First, the hydroxyl group is attached to the spacer and then connected to the desired imidazole or the protected primary amine. The above described derivatives will be utilized for development of analytical kits for a determination of the free steroid hormone.
Keywords: dyagnostics; steriod; sythesis
Project no.: FV20061
Funding provider: GA MPO
Host item entry: Book of Abstracts, ISBN N
Rights: This work is protected under the Copyright Act No. 121/2000 Coll.

Institution: Institute of Chemical Process Fundamentals AS ČR (web)
Original record: http://hdl.handle.net/11104/0289610

Permalink: http://www.nusl.cz/ntk/nusl-389952


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