Original title: New Membranes with Immobilizing Chiral Selector for Racemic Micture Separation.
Authors: Gaálová, Jana ; Cuřínová, Petra ; Stibor, Ivan ; Izák, Pavel
Document type: Papers
Conference/Event: International Conference on Membrane Processes, Prague (CZ), 20180513
Year: 2018
Language: eng
Abstract: Enantiomers exhibit identical properties in the achiral environment, however, they often differ in effectiveness, pharmacological activity and pharmacokinetic profile since the modules with which they interact in biological systems are also optically active [1,2]. Racemic immobilizing chiral selector is present. Five types of membranes with different amount of chiral selector were used. During the pertraction experiments the membranes were subsequently placed between the feed and receiving phase of the pertraction cell. During pertraction experiments we find out, that kinetics of the pertraction significantly influence the enantiomer resolution what indicated that facilitated transport is employed; while enantioselective sorption activity of the membranes reached up to 100%.
Keywords: chiral selector membrane; petraction; racemic mixture
Project no.: GA17-00089S (CEP)
Funding provider: GA ČR
Host item entry: Book of Abstracts, ISBN 978-80-906831-2-9
Rights: This work is protected under the Copyright Act No. 121/2000 Coll.

Institution: Institute of Chemical Process Fundamentals AS ČR (web)
Original record: http://hdl.handle.net/11104/0287968

Permalink: http://www.nusl.cz/ntk/nusl-387541


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