Original title: Interaction of haloperidol with IKto-channels in cardiac cells: a quantitative model
Translated title: Interakce haloperidolu s IKto-kanály u srdečních buněk: matematický model
Authors: Pásek, Michal ; Bébarová, M. ; Matejovič, P. ; Nováková, M.
Document type: Papers
Conference/Event: Human Biomechanics 2006, Hrotovice (CZ), 2006-11-13 / 2006-11-16
Year: 2006
Language: eng
Abstract: [eng] [cze]
In this work, the effect of antipsychotic drug haloperidol (1 µmol/l) on transient outward potassium current (IKto) in rat ventricular myocytes is explored and mathematical model of haloperidol interaction with IKto-channels introduced. Práce popisuje účinek psychofarmaka haloperidolu na přechodný draslíkový proud IKto u srdečních buněk laboratorního potkana a představuje matematický model interakce haloperidolu s příslušnými kanály.
Keywords: haloperidol; IKto-channel; quantitative model
Project no.: CEZ:AV0Z20760514 (CEP), GA305/04/1385 (CEP)
Funding provider: GA ČR
Host item entry: Human Biomechanics 2006, ISBN 80-214-3232-2

Institution: Institute of Thermomechanics AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0138363

Permalink: http://www.nusl.cz/ntk/nusl-36053


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Research > Institutes ASCR > Institute of Thermomechanics
Conference materials > Papers