Original title: The simulation of effect of membrane channel block by propafenone on electrical activity on human atrial cells
Authors: Brožková, K. ; Pásek, Michal ; Šlichta, J.
Document type: Papers
Conference/Event: Conference of the Czech Society of biomechanics with international participation Biomechanics of man 2000, Olomouc (CZ), 2000-11-24 / 2000-11-25
Year: 2000
Language: eng
Abstract: The main aim of this study is to explore the effect of propafenone on suppression of irregular excitations in human atrial cell. A program was designed that contains the computational model of electric activity on human atrial cells and the mathematical model of interaction of propafenone with INa-channels. This integrated model can served for simulations of the drug effects.
Keywords: cardiac cells; propafenone; quantitative modelling
Project no.: CEZ:AV0Z2076919 (CEP)
Host item entry: Biomechanics of man 2000, ISBN 80-244-0193-2

Institution: Institute of Thermomechanics AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0107260

Permalink: http://www.nusl.cz/ntk/nusl-31174


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Research > Institutes ASCR > Institute of Thermomechanics
Conference materials > Papers