Original title: Structural Studies of anti-CA IX Monoclonal Antibody M75 Fab Fragment in Complex with its Epitope Peptide
Authors: Mader, Pavel ; Štouračová, Renata ; Brynda, Jiří ; Závada, Jan
Document type: Papers
Conference/Event: Meeting of the Czech and Slovak structural biologists /3./, Nové hrady (CZ), 2004-03-11 / 2004-03-13
Year: 2004
Language: eng
Abstract: CA IX is a cell surface protein that exerts capacity of binding cell surface receptors, and is associated with several types of human carcinomas. Monoclonal antibody M75 recognizes specifically an epitope identified as six repeats of amino acid sequence PGEEDLP, localized in the proteoglycan like domain of CA IX. Structural study of the M75 Fab fragment in complex with its epitope peptide PGEEDLPGEEDL is presented.
Keywords: antibody; CAIX; structure
Project no.: CEZ:AV0Z5052915 (CEP), GA203/02/0405 (CEP)
Funding provider: GA ČR
Host item entry: Materials Structure in Chemistry, Biology, Physics and Technology, ISSN 1211-5894

Institution: Institute of Molecular Genetics AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0087435

Permalink: http://www.nusl.cz/ntk/nusl-28158


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Research > Institutes ASCR > Institute of Molecular Genetics
Conference materials > Papers