Institute of Molecular Genetics

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2026-01-24
00:12
7th CCP Phenogenomics Conference abstract book
Sedláček, Radislav
The conference focuses on rare diseases and gene therapy research, bringing together a diverse community of experts to advance the field.\n\nRenowned speakers from molecular biology, medicinal chemistry, bioinformatics, animal model development, and preclinical testing will share insights aimed at accelerating the development of gene therapies for rare genetic diseases. The event will also emphasize the translation of experimental gene therapy approaches into clinical research.\n\nThis conference is organized under the research programme “Towards Precision Medicine and Gene Therapy” as part of the Strategy AV21, supported by the Czech Academy of Sciences.

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2023-02-26
00:14
4th CCP Phenogenomics Conference abstract book
Sedláček, Radislav
The fourth CCP Phenogenomics Conference was held as a hybrid meeting. The scientific committee selected the topic of rare diseases: experimental models & delivery of therapies as the main thematic focus of the 2022 Conference. The Conference provided again an excellent opportunity to support networking and interactions among the researchers, CCP staff, users and experts from the commercial sector.

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2022-11-20
00:00
4th CCP Phenogenomics Conference abstract book
Sedláček, Radislav
The fourth CCP Phenogenomics Conference was held as a hybrid meeting. The scientific committee selected the topic of rare diseases: experimental models & delivery of therapies as the main thematic focus of the 2022 Conference. The Conference provided again an excellent opportunity to support networking and interactions among the researchers, CCP staff, users and experts from the commercial sector.

Detailed record
2022-09-28
00:47
3rd CCP Phenogenomics Conference 2021: Abstract Book
Sedláček, Radislav
The Conference was divided into two blocks. The first day was devoted to the theme “Human diseases and models“. The second day was specifically dedicated to preclinical development, including covid-19, which focused on translation of the basic research into the application. The Conference provided an excellent opportunity to support networking and interactions among the CCP users and experts.

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2022-09-28
00:47
2nd CCP Phenogenomics Conference 2020: Abstract Book
Sedláček, Radislav
The Conference was divided into two blocks. The first day was devoted to the theme “Human diseases and models“. The second day was specifically dedicated to preclinical development, including covid-19, which focused on translation of the basic research into the application. The Conference provided an excellent opportunity to support networking and interactions among the CCP users and experts.
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2021-03-07
00:01
2nd CCP Phenogenomics Conference 2020
Sedláček, Radislav
The conference was divided into two blocks. The block focused on the theme “From chemistry via preclinical pipeline to therapeutics“, which emphasized the translation of the basic research into the application. The second block was specifically devoted to presentation of CCP users and cooperation partners projects working in the field of immunology, hematology, genetic base of diseases, and neurobiology.

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2011-07-01
17:02
Mikroskopie 2008
Hozák, Pavel
Dvoudenní konference reagující na nejnovější trendy v světelné a elektronové mikroskopii a jejich dopad na mikroskopické badatele v českých zemích a na slovensku. Prezentovány jsou příspěvky jak z oblasti biomedicínské, tak z oblasti fyziky a materiálových věd. Konference se koná v lyžařském sportovním areálu v srdci českomoravské vysočiny a je zakončena opulentním rautem s ochutnávkou vín.

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2011-07-01
16:58
Regulace syntézy ribozomů v bakteriích
Krásný, Libor
Rychle rostoucí bakterie potřebují velké množství ribozomů pro pokrytí potřeby zvýšené buněčné translace. Bakterie v podmínkách omezené výživy mají potřebu ribozomů nízkou kvůli šetření energií. Počet ribozomů je regulován na úrovni transkripce ribozomální RNA (rRNA).

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2011-07-01
16:57
Původ proteinů kančí semenné plazmy
Maňásková, Pavla ; Kyselová, Vendula ; Tichá, M. ; Jonáková, Věra
Spermadhesiny byly nalezeny pomocí svých protilátek v kančí epididymální tekutině, ale DQH a beta microseminoprotein nikoli. Nepřímá imunofluorescenční technika byla použita pro odhalení distribuce proteinů semenné plasmy na řezech tkání kančích reprodukčních orgánů. mRNA beta-MSP v testes, semenných vacích a prostatě.

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2011-07-01
16:57
Vazebné vlastnosti proteinů kančí semenné plazmy v reprodukčním procesu
Jonáková, Věra ; Maňásková, Pavla ; Liberda, J. ; Tichá, M.
Proteiny kančí semenné plasmy (spermadhesiny a DQH protein) se váží na povrch spermie při ejakulaci. Vazba spermie k epiteliálním buňkám oviduktu a ke glykoproteinům zony pellucidy je zprostředkována protein-sacharidovými interakcemi (lektin-like).Tyto interakce hrají roli v tvorbě oviduktálního rezervoáru spermií, v uvolnění kapacitovaných spermií z povrchu oviduktu a ve vazbě spermie na zonu pellucidu vajíčka.

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