Original title: Voltammetric Determination of Cytostatic Using Silver Solid Amalgam Electrode
Authors: Barek, J. ; Fischer, J. ; Konečná, B. ; Kratzer, J. ; Hrušková, M. ; Navrátil, Tomáš ; Novotný, Ladislav ; Josypčuk, Bohdan ; Zima, J.
Document type: Papers
Conference/Event: Moderní elektrochemické metody /23./, Jetřichovice (CZ), 2003-05-20 / 2003-05-22
Year: 2003
Language: eng
Abstract: Modern polarographic and voltammetric methods at mercury meniscus-modified silver solid amalgam electrode (m-AgSAE) were proved to be suitable for the determination of a number of polarographically active cytostatic drugs. The voltammetric determination of 6-mercaptupurine (6-MP), 6-thioguanine (6-TG), Mitoxantrone (MX, CAS No.: 65271-80-9, CAS. Name: 1,4-Dihydroxy-5,8-bis[{2-[(2-hydroxyethyl)amino]ethyl}amino]-9,10-anthracenedione), and Doxorubicin (DR, CAS No.: 23214-92-8, CAS Name: (8S-cis)-10-[(3-Amino-2,3,6-trideoxy--L-lyxohexapyranosyl)oxy] - 7, 8, 9, 10 - tetrahydro-6, 8, 11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphtacenedione) were studied.
Keywords: 6-mercaptupurine; doxorubicin; mitoxantrone
Project no.: CEZ:AV0Z4040901 (CEP), 101/02/U111/CZ
Funding provider: GIT
Host item entry: Moderní elektrochemické metody, ISBN 80-86238-29-6

Institution: J. Heyrovsky Institute of Physical Chemistry AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0078186

Permalink: http://www.nusl.cz/ntk/nusl-26898


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Conference materials > Papers