Original title: Effect of Colloidal Silica Dioxide on Rheological Properties of Common Pharmaceutical Excipients.
Authors: Majerová, D. ; Tran, D.T. ; Kulaviak, Lukáš ; Růžička, Marek ; Štěpánek, F. ; Zámostný, P.
Document type: Papers
Conference/Event: International Conference on Process Integration, Modeling and Optimization for Energy Savings and Pollution Reduction (PRES) /19./, Prague (CZ), 20160827
Year: 2016
Language: eng
Abstract: In this work, the rheological properties of silicified microcrystalline cellulose and pregelatinized starch was investigated in comparison to the characteristics of pure excipients. At first, pure materials were analysed on scanning electron microscopy (SEM) to obtain their particle size distribution and particle shape. Also the rheological properties of all three substances were examined by the Freeman FT4 rheometer. The observed properties were in accordance with known characteristics and typical behaviour of the excipients.
Keywords: comparison; pharmaceutical excipients; rheological properties
Host item entry: Abstracts, ISBN N.
Rights: This work is protected under the Copyright Act No. 121/2000 Coll.

Institution: Institute of Chemical Process Fundamentals AS ČR (web)
Original record: http://hdl.handle.net/11104/0261924

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