Original title: Nanostructured gold electrodes for determination of glucose in blood
Authors: Farka, Z. ; Juřík, T. ; Kovář, D. ; Podešva, Pavel ; Foret, František ; Skladal, P.
Document type: Papers
Conference/Event: CECE 2015. International Interdisciplinary Meeting on Bioanalysis /12./, Brno (CZ), 2015-09-21 / 2015-09-23
Year: 2015
Language: eng
Abstract: Fast and sensitive devices for monitoring of glucose are crucial in today’s medicine. Most of the commercial glucometers are currently based on enzymatic catalysis which provides reasonable sensitivity but has a drawback in limited enzyme stability. With the development of novel surfaces, new generation of non-enzymatic sensors characterized by high sensitivity and stability is emerging. In this work, gelatin-templated nanostructured gold electrodes were developed and applied for non-enzymatic glucose determination. The analysis was done by direct electrochemical oxidation during cyclic voltammetry and amperometry with the limit of detection at 1.3 μM. The ability to detect physiological levels glucose in presence of interferents was demonstrated on deproteinized human blood serum.
Keywords: glucometers; human blood serum; monitoring of glucose; non-enzymatic glucose determination
Host item entry: CECE 2015. 12th International Interdisciplinary Meeting on Bioanalysis, ISBN 978-80-904959-3-7

Institution: Institute of Analytical Chemistry AS ČR (web)
Document availability information: Fulltext is available at external website.
External URL: http://www.ce-ce.org/CECE2015/CECE%202015%20proceedings_full.pdf
Original record: http://hdl.handle.net/11104/0251787

Permalink: http://www.nusl.cz/ntk/nusl-200995


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Research > Institutes ASCR > Institute of Analytical Chemistry
Conference materials > Papers