Original title: Capillary isotachophoresis with ESI-MS detection: Ultrahighly sensitve analysis of diclofenac and ibuprofen in waters
Authors: Malá, Zdeňka ; Gebauer, Petr ; Boček, Petr
Document type: Papers
Conference/Event: CECE 2015. International Interdisciplinary Meeting on Bioanalysis /12./, Brno (CZ), 2015-09-21 / 2015-09-23
Year: 2015
Language: eng
Abstract: This work shows that CE-MS can reach same sensitivity as HPLC-MS, when it is peformed in the ITP-MS mode. By combination of ITP-ESI-MS with an offline SPE preconcentration step and optimization of MS signal collection, LODs below 2x10-12 M can be reached, corresponding to of 0.6 ng/L of diclofenac (Dic) and 0.4 ng/L of ibuprofen (Ibu), compatible to that of SPE-HPLC-MS.
Keywords: CE-MS; HPLC-MS; ITP-ESI-MS; ITP-MS
Project no.: GA13-05762S (CEP)
Funding provider: GA ČR
Host item entry: CECE 2015. 12th International Interdisciplinary Meeting on Bioanalysis, ISBN 978-80-904959-3-7

Institution: Institute of Analytical Chemistry AS ČR (web)
Document availability information: Fulltext is available at external website.
External URL: http://www.ce-ce.org/CECE2015/CECE%202015%20proceedings_full.pdf
Original record: http://hdl.handle.net/11104/0250988

Permalink: http://www.nusl.cz/ntk/nusl-200891


The record appears in these collections:
Research > Institutes ASCR > Institute of Analytical Chemistry
Conference materials > Papers