Original title: Polymer anticancer drugs with pH- and enzyme-dependent activation
Translated title: Polymerní protirakovinná léčiva s pH- a enzymaticky závislou aktivací
Authors: Etrych, Tomáš ; Chytil, Petr ; Strohalm, Jiří ; Jelínková, Markéta ; Kovář, Marek ; Říhová, Blanka ; Ulbrich, Karel
Document type: Papers
Conference/Event: Nové Hrady Winter Symposium on Structure and Function of Proteins /1./, Nové Hrady (CZ), 2004-01-22 / 2004-01-24
Year: 2004
Language: eng
Abstract: [eng] [cze]
Water-soluble synthetic polymers and their conjugates with antibodies, oligopeptides or saccharides proved a potential targetable drug delivery system. Recently, copolymers of N-(2-hydroxypropyl)methacrylamide (HPMA) have been developed in our laboratory as polymeric carriers of drugs. Vodorozpustné syntetické polymery a jejich konjugáty s protilátkami, oligopeptidy nebo sacharidy jsou potenciálními systémy pro cílený transport léčiv. V poslední době byly k tomuto účelu v naší laboratoři vyvinuty kopolymery N-(2-hydroxypropyl)methakrylamidu.
Keywords: copolymers of N-(2-hydroxypropyl)methacrylamide; pH-sensitive bond; targetable drug delivery system
Project no.: CEZ:AV0Z4050913 (CEP), GA305/02/1425 (CEP)
Funding provider: GA ČR
Host item entry: Proceedings

Institution: Institute of Macromolecular Chemistry AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0008721

Permalink: http://www.nusl.cz/ntk/nusl-19338


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Research > Institutes ASCR > Institute of Macromolecular Chemistry
Conference materials > Papers