Original title:
Sensor based on Förster resonance energy transfer with quantum dot
Authors:
Lišková, Marcela ; Datinská, Vladimíra ; Klepárník, Karel ; Foret, František Document type: Papers Conference/Event: CECE 2012. International Interdisciplinary Meeting on Bioanalysis /9./, Brno (CZ), 2012-11-01 / 2012-11-02
Year:
2012
Language:
eng Abstract:
Förster resonance energy transfers (FRET) are based on the nonradiative transfer of energy between a donor and acceptor dye in the distance 1-10 nm. With respect to this, quantum dots (QDs) with a high absorbance can serve as suitable donors of energy in FRET. Here, we present architectures of two sensors based on QD conjugates useful in imaging and diagnostics of cancer. One sensor, based on an oligonucleotide conjugate, can be used for the detection of complementary oligonucletide chains. The other was designed for the detection of enzymes inside cells.
Keywords:
cells; Förster resonance energy transfers; quantum dots Project no.: CEZ:AV0Z40310501 (CEP), GAP301/11/2055 (CEP), GAP206/11/2377 (CEP), EE2.3.20.0182, GA203/08/1680 (CEP) Funding provider: GA ČR, GA ČR, GA MŠk, GA ČR Host item entry: CECE 2012. 9th International Interdisciplinary Meeting on Bioanalysis, ISBN 978-80-904959-1-3 Note: Související webová stránka: http://hdl.handle.net/11104/0215651
Institution: Institute of Analytical Chemistry AS ČR
(web)
Document availability information: Fulltext is available in the digital repository of the Academy of Sciences. Original record: http://hdl.handle.net/11104/0215651