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Metabolic and genetic risks of development of non-alcoholic fatty liver disease in patients after liver transplantation and its impact on patient and graft survival
Míková, Irena ; Trunečka, Pavel (advisor) ; Červinková, Zuzana (referee) ; Brůha, Radan (referee)
Nonalcoholic fatty liver disease (NAFLD) occurs frequently not only in the general population, but also in liver transplant (LT) recipients. The data about prevalence, evolution, causes and significance of steatosis in patients after LT are limited. In a large retrospective study in LT recipients with histological evaluation of steatosis, we found high prevalence of steatosis (56,4 %) and steatohepatitis (10,4 %), the prevalence of steatosis increased after LT. Pretransplant predictors of steatosis included alcoholic cirrhosis and high BMI, whereas increased alkaline phosphatase and mycophenolate mofetil given initially were protective. Posttransplant predictors of steatosis included BMI, serum triglycerides, alcohol consumption and presence of type 2 diabetes mellitus, whereas increased serum creatinine was protective. Presence of significant steatosis/steatohepatitis was not associated with increased grade of fibrosis. There was no difference between the occurrence of steatosis in surviving and lost grafts. Survival of patients with/without significant steatosis was similar with a trend to higher long-term mortality of patients with significant steatosis. In the evaluation of the impact of TM6SF2 rs58542926 and PNPLA3 rs738409 genotypes of the donor and recipient on pathophysiology of steatosis...
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Analysis of Communication Flows in a selected Organization
Růžková, Michaela ; Hiršová, Miloslava (advisor) ; Míková, Irena (referee)
This bachelor's thesis analyses communication flows in a selected organisation. Its main aim is to assess the current state of internal communication within the organisation. The assessment was carried out using an analysis of communication flows, forms and tools. The results of the analysis were used to identify areas where communication problems occur. Besides this, the thesis aims to find out whether the organisation's employees are sufficiently informed, or whether they are exposed to an excessive amount of information, or even misinformed. Lastly, the thesis is, based on the identified problematic areas, recommend how the level of internal communication could be improved.
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Adaptation of new Workers in a selected Company
Kurhan, Katsiaryna ; Míková, Irena (advisor) ; Hiršová, Miloslava (referee)
The bachelor thesis is focused on the process of adapting new employees in the organization. In the practical part I will deal with the description of the individual aspects of the process of adaptation, what it consists of and how it is affected. In the practical part, I will focus on the adaptation process in one of the largest American resort and evaluate its success.
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Analysis of training needs in the banking sector
Prišticová, Dáša ; Míková, Irena (advisor) ; Marková, Mária (referee)
The bachelor thesis is focused on the analysis of training in a particular bank. The aim of the final thesis is the analysis of training and development, combined with the finding of satisfaction and usability of the trained topic in practice. The survey was realized using a questionnaire. The questionnaire has been sent to the employees participating in the selected training. The point of interest are the individual parts of the course, which represent important steps in achieving the overall assessment of the training. The system of education is evaluated on the basis of the theoretical information as well as the results of the research. These results can be used to improve the system of training and development in the bank, where research was made of.
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Analysis of Amateur Theater Group FaMa
Horká, Dora ; Musil, Martin (advisor) ; Míková, Irena (referee)
The main goal of this thesis is to analyze Amateur Theater Group FaMa with intention on director as manager. Results will be collected with structured internal questionnaire using the CAWI technique. Another goal is to analyze FaMa´s existing economy. Theses coming-out will be commented results and following recommendations for FaMa´s future activities.
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Motivation System in a chosen Company - Analysis of Incentive Plan
Poupová, Klára ; Míková, Irena (advisor) ; Hiršová, Miloslava (referee)
This bachelor thesis is focused on the motivation of employees in the selected company XY. The aim of my bachelor´s thesis is to evaluate the current status of the current incentive plan and further analyse it. For the next will be detected the impact of this motivation system of the company to employees of the organization. Firstly, were determined the research questions to which they sought answers. With the help of the questionnaire survey will be found the relevant data to determine the necessary information. The questionnaire contains questions relating to existential needs, growth needs and relationship needs, which will help give a comprehensive view of the current situation in the company. Subsequently, they will be developed some of the dependencies of individual data that will help answer research questions. The result of the work is a document that a company can use to improve the incentive plan.
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Effects of Stress on Performance in the Workplace
Hroníková, Eliška ; Hiršová, Miloslava (advisor) ; Míková, Irena (referee)
This Bachelor's thesis is focused on the effects of stress on the productivity of employees. The goal is to find out what type of stress and how much influence it has on workers, how it effects their work behavior and their productivity. The basis for putting together the research were the stressor selected from publications from the authors featured in the theoretical part and adapted to the situation in the organization. Partial goals are to determine what impact the stressors have on mental well-being. Examined are both, the negative and positive effects of stressors. Proposed recommendations which could help the management of organization to prevent negative influences or their complete elimination are based on theoretical knowledge and discovered results.
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Social aspects of workplace communication
Klimeš, Josef ; Hiršová, Miloslava (advisor) ; Míková, Irena (referee)
AKTUALIZOVAT Communication and presentation skills, so-called. soft skills are an integral part of the manager´s daily performance. Often they´re the key aspects that determine the success or failure of a very single person. Mistakenly, these skills are considered innate or unalterable. The thesis supposed to convince the reader to the contrary opinion. The theoretical part is combining the knowledge gained from literature and presentation skills acquired through practice. The research is focused on evaluating of the online questionnaire distributed at ŠKODA AUTO a.s. In conclusion, attention is paid to the interpretation of results with suggestions for their improvements. The aim of this work is to serve as a technical manual of basic communication and presentation skills of managers.
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Sensation of Jeopardy as a Possible Source of Work Motivation
Adamcová, Lenka ; Hiršová, Miloslava (advisor) ; Míková, Irena (referee)
The aim of this bachelor thesis is to determine whether the sensation of jeopardy may be a source of motivation to work, or, conversely, it plays a significant role in motivating staff. The survey has dealt with motivational factors (including sensation of jeopardy) and divided them according to Herzbergs motivation theory on motivators and higyene factors where the degree of motivation and degree of satisfaction at the workplace are determined. The operational objective is to determine the impact of a sensation of jeopardy on the overall work atmosphere, which is connected to the relations with superiors and relations with workers at the same level. Subsequently, the working atmosphere examined the presence of sensations of jeopardy, which may cause rivalry or, conversely, mutual support. Required data were obtained by a questionnaire. In conclusion, my thesis summarizes the key findings and recommendations for the organization, which was the objected of the the survey.
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Changes in Organizational Culture in a chosen Organization
Pleskačová, Lubica ; Hiršová, Miloslava (advisor) ; Míková, Irena (referee)
The aim of this thesis is to describe present culture of a chosen organisation where an update of company´s values has been implemented and the Code of Ethics was created and to compare this new company´s environment with the one before. This thesis is divided into two parts. The first part is focused on the theoretical background of this issue, i.e. specification of the organisational culture, its changes and The Code of Ethics. The second part is focused on analysis of collected data, which were collected by the questionnaire and by the interview. The conclusion is focused on a summary of found results and providing possible recommendation to the selected organisation.
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