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Phase-separated systems biopolymer-lipid
Kubalová, Barbora ; Pekař, Miloslav (referee) ; Mravec, Filip (advisor)
This diploma thesis deals with experimental study of interaction based on polymer-lipid system. The main goal was to investigate interaction leading to phase separation. Three anionic polyelectrolytes were selected for this purpose: sodium hyaluronate, sodium chondroitin-6-sulfate and sodium poly(4-styrenesulfonate). The liposomes were formulated by sonication of lipid – cationic 1,2-dipalmitoyl-3-trimethylamonium-propane (chloride salt) and zwitterionic 1,2-dipalmitoyl-sn-glycero-phosphocholine. It was found that the phase separation occured at specific ratio of DPTAP and selected polymer. It was also explored that the strong electrostatic interaction which leads to the phase separation can be weaken by increasing the ionic strength in the sample. As we aspected the systems contain the hydrophobic domain and therefore these are able to incorporate hydrophobic substances in their structure.
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The Role of Violence in Blood Meridian and The Road by Cormac McCarthy
Kubalová, Barbora ; Robbins, David Lee (advisor) ; Procházka, Martin (referee)
Violence has always been conspicuously present in the American nation, its culture and literature. Considering the immoderate abundance of violence in current entertainment industry, it would seem natural for the emotions to be dulled and able to process any abhorrent excess of violence; the reactions that both Blood Meridian and The Road by the American author Cormac McCarthy have gathered are thus all the more surprising. Face to face with the novels' unspeakable evil, many readers do recoil in horror and the pervasive violence of McCarthy's writings has provoked a wide range of critical perception. The novels may differ significantly in the setting − Southwestern United States of the 19th century in Blood Meridian as opposed to post-apocalyptic future of The Road - but the apparent gulf between both groups of characters and mainly between them and the reader is only another ruse of McCarthy's scheme, whereby he unveils uncomfortable truths about humankind. Although his meticulous study of sources might support the inevitability, even a penchant for bloodshed and carnage in specific conditions, it would be erroneous and contrary to McCarthy's portrayal to imply that it is anomalous rather than representative. The hostility in the novels should not be understood as a feature of a particular region or...
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Evaluation of training effect with elements of proprioceptive neuromuscular facilitation on shooting velocity by female handball players of the 1st league in the Czech Republic
Kubalová, Barbora ; Pavlů, Dagmar (advisor) ; Pánek, David (referee)
Title: Evaluation of training effect with elements of proprioceptive neuromuscular facilitation on shooting velocity by female handball players of the 1st league in the Czech Republic Objectives: The aim of this study is to determine, whether completing an exercise program based on elements of proprioceptive neuromuscular facilitation and using elastic band resistance can influence shooting velocity by female handball players. Methods: In this randomized control study 25 female handball players, who are playing the 1st league in Havlíčkův Brod, were divided into experimental (n = 13) and control group (n = 12). Both groups underwent an initial shooting velocity measurement (PRE) using radar gun Stalker Pro II. Then experimental group completed 6-week exercise program, based on D2 flexion and extension from proprioceptive neuromuscular facilitation against elastic band resistance. The control group did not perform any exercise like that. Both groups otherwise completed the same training program during the preparatory phase. After that the shooting velocity was again measured (POST). The results were statistically processed in the Jamovi using two-way repeated measures ANOVA. Results: There was a statistically significant improvement in shooting velocity of the control and experimental groups in the...
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Case Study of Physiotherapy Treatment of a Patient with the Diagnosis Impingement Syndrome
Kubalová, Barbora ; Satrapová, Lenka (advisor) ; Šachová, Dana (referee)
Title: The case study of physiotherapy treatment of a patient with the diagnosis of impingement syndrome. Objectives: The aim of this bachelor's thesis is to summarize the theoretical knowledges about the diagnosis of impingement syndrome in its first part. The following part is focused on elaboration of the case study of the patient with this diagnosis. Methods: This bachelor's thesis was drawn up on the basis of intership in the Centrum léčby pohybového aparátu in Prague between 7. 1. 2019 - 1. 2. 2019. This bachelor's thesis consists of two parts - the general one and the special one. The objective of the general part, which resumes information drawn from the scientific literature, is to approach the issue of impingement syndrome. The special part includes a case study of the patient with this diagnosis and contains the initial kinesiological analysis, the aim of the therapy, description of the therapy and its final evaluation. Results: I have managed to summarize the theoretical knowledges of the problem of the diagnosis in the general part of the thesis. In the special part I have processed the patient's case study. In the course of the therapy, the patient's condition improved subjectively by 20%. In an objective evaluation, the greatest improvement occurred in the range of motion of the...
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The Role of Violence in Blood Meridian and The Road by Cormac McCarthy
Kubalová, Barbora ; Robbins, David Lee (advisor) ; Procházka, Martin (referee)
Violence has always been conspicuously present in the American nation, its culture and literature. Considering the immoderate abundance of violence in current entertainment industry, it would seem natural for the emotions to be dulled and able to process any abhorrent excess of violence; the reactions that both Blood Meridian and The Road by the American author Cormac McCarthy have gathered are thus all the more surprising. Face to face with the novels' unspeakable evil, many readers do recoil in horror and the pervasive violence of McCarthy's writings has provoked a wide range of critical perception. The novels may differ significantly in the setting − Southwestern United States of the 19th century in Blood Meridian as opposed to post-apocalyptic future of The Road - but the apparent gulf between both groups of characters and mainly between them and the reader is only another ruse of McCarthy's scheme, whereby he unveils uncomfortable truths about humankind. Although his meticulous study of sources might support the inevitability, even a penchant for bloodshed and carnage in specific conditions, it would be erroneous and contrary to McCarthy's portrayal to imply that it is anomalous rather than representative. The hostility in the novels should not be understood as a feature of a particular region or...
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Phase-separated systems biopolymer-lipid
Kubalová, Barbora ; Pekař, Miloslav (referee) ; Mravec, Filip (advisor)
This diploma thesis deals with experimental study of interaction based on polymer-lipid system. The main goal was to investigate interaction leading to phase separation. Three anionic polyelectrolytes were selected for this purpose: sodium hyaluronate, sodium chondroitin-6-sulfate and sodium poly(4-styrenesulfonate). The liposomes were formulated by sonication of lipid – cationic 1,2-dipalmitoyl-3-trimethylamonium-propane (chloride salt) and zwitterionic 1,2-dipalmitoyl-sn-glycero-phosphocholine. It was found that the phase separation occured at specific ratio of DPTAP and selected polymer. It was also explored that the strong electrostatic interaction which leads to the phase separation can be weaken by increasing the ionic strength in the sample. As we aspected the systems contain the hydrophobic domain and therefore these are able to incorporate hydrophobic substances in their structure.
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Modification of medical hyaluronan hydrogels
Kubalová, Barbora ; Sedláček, Petr (referee) ; Venerová, Tereza (advisor)
The aim of this bachelor´s thesis was to modify the physically cross-linked hyaluronan hydrogels based on polymer-surfactant systems in order to possibly utilize them in the medical applications. Due to their antibacterial properties and viscoelasticity they are characterized as the perspective systems which can find their applications in medicine. The diversification was based on the replacement of the hyaluronan polymer networks for other polymers. Two polymers were selected for these purposes: polymer 1 and polymer 2. x% solution formed from two polymers was prepared carrying the specific amount of hyaluronan in the polymer blend of a %, b %, c %, d % and e %. The samples containing the x% system of mixed polymers which carried the specific amount of hyaluronan (e %) were measured and a surfactant solubilization ability of the hydrophilic dye Sudan red G was determined in order to confirm the physical crosslinking of the hydrogel, and the frequency rheological tests were also performed.
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