National Repository of Grey Literature 43 records found  1 - 10nextend  jump to record: Search took 0.01 seconds. 
Disposition and metabolism of cannabinoids.
Hložek, Tomáš ; Balíková, Marie (advisor) ; Miovský, Michal (referee) ; Šustková, Magdaléna (referee)
This thesis describes in the form of a commentary on own original publications research on the problems of cannabinoids, ie. phytocannabinoids and some synthetic cannabinoids, their pharmacokinetics and effects. The work consists of four thematic areas: the pharmacokinetics of delta-9- tetrahydrocannabinol (THC) and cannabidiol (CBD) in rats, depending on the route of administration; THC concentration time profile in humans (after inhalation) and implications for transport safety; the pharmacokinetic profile of synthetic cannabinoids in rats; extraction and determination of phytocannabinoids in plant material. The first part of the thesis was to determine pharmacokinetic profiles of THC, CBD and combination thereof (1:1 weight ratio) in rats with respect to administration common in humans, i.e. inhalation, oral and subcutaneous administration. THC, its metabolites (11-hydroxy-tetrahydrocannabinol, 11-OH-THC; 11-nor-delta-9- carboxytetrahydrocannabinol, THCOOH) and CBD concentrations in serum and brains of animals were monitored at the 24 hours experimental interval during the study. Except for inhalation administration, co-administration of CBD inhibited THC metabolism (after both oral and subcutaneous), resulting in an increase in THC concentrations in both serum and brain of the rats relative to...
Role of Motivation for Physical Activity in Treatment of Addictions
Prunerová, Anna ; Riegel, Karel Dobroslav (advisor) ; Miovský, Michal (referee)
Title of diploma thesis: Role of Motivation for Physical Activity in Treatment of Addictions Abstract: Motivation for a healthy habit in the form of physical activity may be beneficial for patients seeking abstinence. Physical activity take part of the treatment program and can improve the overall prognosis of treatment. It can improve an individual's psyche and prevent potentially harmful habits associated with drug abuse. The aim of this study was to determine the motivation of patients for physical activity during three-month treatment at the Department of Addictology in Prague. The research group consisted of 72 patients in standard 3-months inpatient treatment. Following measures were used for data collection: 1) Behavioural Regulation in Exercise Questionnaire (BREQ-2) and Personality Inventory for DSM-5 (PID- 5); 2) anthropometrics; 3) body composition data from "InBody 230"; 4) training diaries. According to the results, 72 % of patients were treated with alcohol dependence. Excellent internal consistency values of the PID-5 facets and satisfactory to good internal consistency values of BREQ-2 on the item level were obtained. Significant correlations of the PID-5 facets and domains of the BREQ-2 confirm criterion validity in terms of motivation. Type of motivation significantly varies according type...
Analysis of the rehabilitation component of a aftercare program based on the "Apolinář" model of treatment of addictive substances
Ostrčilová, Kateřina ; Miovský, Michal (advisor) ; Svěcená, Kateřina (referee)
Addiction treatment includes lots of treatment interventions and kinesiotherapy treatment should undoubtedly belong to them as well. The thesis puts focus on the aftercare program of the Apolinář model in inpatient wards with recurrent stays of clients who have the same structure as basic institutional treatment. Despite the busy daily program there should always be room for physical activity. The aim of the work is to map and compare the concept of rehabilitation in the current setting of Apolinář model of addiction treatment with the concept of rehabilitation in the field of physiotherapy. Next main research topic will be the method of ensuring rehabilitation, whether it is appropriate to the health of the clients and possibly assessing the possibilities of the physiotherapist in the nursing team. The research tool for data collection was evaluation by formative approach. The evaluation was carried out in inpatient wards of the Clinic of Addictology. The research sample consisted of a treatment program and was selected by the method of deliberate selection. The unit of the research file is therefore not the patient. Data collection was executed in the form of observations from the perspective of a researcher who is also an expert in physiotherapy. In addition, further data will also be collected...
The dynamics of asymmetry in healthcare communication
Francová, Veronika ; Rendl, Miroslav (advisor) ; Miovský, Michal (referee) ; Šmídová, Iva (referee)
The communication between patient and healthcare professional is one of the keys to patients' adherence to treatment and to successful therapy; hence communication is a relevant and widely discussed issue of our healthcare. The relationship between a patient and a health worker is rather asymmetric, which affects the course of their communication. This asymmetry is based on the patient made weak (helpless) by illness whereas the expert/physician is in the position to prescribe treatment with the health staff administering such treatment. The aim of the study is to explore the extent of asymmetry in Czech hospitals, the situations where it is most pronounced and the changing structure of asymmetry as seen from the patients' point of view. We conducted a qualitative analysis of 16 interviews with respondents who have experienced hospitalization. The analysis focuses on the psychological level of communication and on the dynamic process in which the asymmetry is being negotiated. We have proved that there is an a priori asymmetry in the relationship, which, under certain circumstances, is effective for the treatment. The asymmetry is being continually negotiated throughout the communication as it fluctuates within four areas: (1) providing information, (2) rules and practices of the hospital, (3)...
Study programme addictology and its graduates' characteristics analysis in the context of the field addictology development.
Pavlovská, Amalie ; Miovský, Michal (advisor) ; Tóthová, Valerie (referee) ; Vaska, Ladislav (referee)
Study programme addictology and its graduates' characteristics analysis in the context of the field addictology development Amalie Pavlovská ABSTRACT Background: The addictions field has a long and diverse history including development of education for professionals who work in it. In last decades we witness an emergence of a new profession of addiction specialist. Based on analysis of the Czech study programme of addictology and the overview of similar programmes in abroad we identified a need for feedback how the graduates in specialized discipline are successful in entering the labour market, and integration into the existing service systems. Such an extensive survey has never been conducted in the CR, abroad we found only limited attemps. Aims: The main aim was to find out the employability rate of study programme addictology graduates and its specific characteristics, both from the view of the graduates and their possible emloyers. Methods: The sample was created by two groups of respondents, addictology graduates and employers from the addictological services. For graduates the total sampling was used, the number of questionnaires returned was almost 60%. The employers sampling reflected all regions of the CR and all types of organizations. The sample was created by 18 organizations. For the...
Initial interview with addicted people in the context of psychodynamic approach
Richterová, Lenka ; Šťastná, Lenka (advisor) ; Miovský, Michal (referee)
Background: A initial interview with addicted people is described as a mapping of the patient's risk behavior in relation to the use of addictive substances. It also includes an assessment of the overall condition of the patient and subsequent determination of the therapeutic plan. It is a complex examination that which takes time for 60 minutes. The question is what should we do in this interview. How to make a plan for treatment with the patient. Objective: The aim of this thesis is to propose the structure of an aditological examination for the outpatient treatment center named Adiktologicka ambulance. The next step is to do the verification of the interview in practice. Methods: On the basis of professional literature, we formulate the possible contents of the "adictological input" exercise. We are interested not only in what to do but also how. We work in a psychodynamic context. Subsequently, we propose initial interview for addected people in the outpatient treatment center for addiction. We highlight the importance of the institutional context. The interview must match the focus and tasks of the certain institution. Finally, we briefly present the experience of the worker with addicted people. Discussions and Conclusions: We found out that an initial examination took more than one hour....
Sexuality of Marihuana Users
Schneider Hrouzková, Alexandra ; Weiss, Petr (advisor) ; Niederlová, Markéta (referee) ; Miovský, Michal (referee)
Objectives: As part of the research issue, we tracked six sub-objectives of the research. The first objective of the research was to describe the sexual behavior of marihuana users in selected areas of sexuality based on data obtained from the questionnaire survey. The presented research was aimed at heterosexual men who regularly use marihuana at a frequency of once a week to daily. The second objective was to find a link between the frequency of marihuana use and selected areas of sexuality. The third objective of our work was to find a link between the length of marihuana use and selected areas of sexuality. The fourth objective of the research was to find a link between the influence of the use of other psychoactive substances on marihuana users in selected areas of sexuality. The fifth objective of our work was to find out the links between tobacco use in a marihuana user group and selected areas of sexuality. The sixth objective was to find a link between the use of marihuana and erectile function, respectively dysfunctions, according to The International Index of Erectile Function (IIEF-5). Methods: For research purposes, we chose a quantitative type of study. The sample comprised 392 respondents, regular heterosexual marihuana users using marihuana at least once a week. A non-standardized...
Monitoring, Evaluation and Research on Effectiveness of Alkohol Treatment on an International Level with European Added Value
Stanislav, Vladimír ; Kalina, Kamil (advisor) ; Miovský, Michal (referee)
Background: Alcohol use disorders belong among the ten leading causes of Years Lost due to Disability in high-income countries. Poland, Czech Republic, and the Slovak Republic are countries with high alcohol consumption. The specific inpatient psychotherapeutic program is basic treatment approach in patients suffering from alcohol dependency. The theory of change assumes that therapeutic approaches should be adapted to the stage of change in which the patient actually is. Aim: To examine the state of readiness to change at the beginning and the end of inpatient short (six weeks) and long (12 weeks) therapeutic program in Slovak Republic, Poland, and the Czech Republic. To compare readiness to change with insight and motivation. To find, whether patients change and how patients change advances in alcohol treatment. Methods: Total 380 alcohol dependent inpatients (282 men and 98 women) were examined using International Statistical Classification of Diseases and Related Health Problems- 10th Revision (ICD- 10), World Health Organization (1992). Alcohol Use Disorders Identification Test (AUDIT), The Stages of Change Readiness and Treatment Eagerness Scale (SOCRATES), Readiness to Change Questionnaire (RCQ), and Demographic Questionnaire. All analyses were calculated using the SPSS (Statistical Packages...
Influence of eating habits on psychopathological symptoms should present clients with mafestations in therapeutic community for treatment of addiction.
Košťáková, Martina ; Miovský, Michal (advisor) ; Minařík, Jakub (referee)
ABCTRACT BACKGROUND: Currently, the diagnosis of ADHD is highly debated. Symptoms pass from childhood to adulthood. It turns out that people who according to the questionnaire YFAS meet the diagnostic criteria for dependence on food, show more comorbidity of other disorders such as binge eating, depressive, or ADHD. OBJECTIVE: The research problem and the aim of the diploma thesis is to find out what effect the regular diet regimen has on the diagnosis of food dependence in clients who are being treated in residential treatment in the treatment community of NL dependence. Assess whether a food addiction is more likely to suffer from ADHD symptoms and symptoms of psychopathology according to the SCL - 90 questionnaire. METHODS: The thesis is based on data from the GAČR ADHD project. The research was conducted in 5 therapeutic communities in the Czech Republic. The YFAS, DIVA and SCL- 90 questionnaires were used for the research. Test cells were collected in 4 waves of data collection, but only the first and second wave of data collection are used in this work because we are interested in data about clients on arrival and during the stay. Of the other questionnaires used in the GAČR ADHD project, very short case studies were developed and only for people who were addicted to food. RESEARCH FILE: The thesis is...
The origin and historical development of psychiatric hospital Červený Dvůr
Debnar, Alexandr ; Šejvl, Jaroslav (advisor) ; Miovský, Michal (referee)
Background: Alcohol treatment in facilities that have adopted the so-called apolinar model has a long tradition in our country. A certain "basic trio" of institutions based on this model was formed by the above mentioned Apolinář, as its carrier and flagship. Another one was psychiatric hospital Lojovice in 1958, later intended for women only. The last one, Červený Dvůr near Český Krumlov was found in 1960s. It became the largest specialized institution for treatment of alcohol addiction in the former Czechoslovakia. Goals: Mapping the history of today's psychiatric hospital Červený Dvůr with the focus on these partial goals: Origin and development, in the initial stage with LSD treatment and the beginning of artetherapy. Find out what kind of patients was the treatment determined for. How the capacity varied and how the program differed in each stage of development. In addition, people who have somehow influenced the origin, development, and therapeutic program. Also personnel changes and interconnection of the significant monument and medical institution. Methods: A document analysis, which is a search for suitable sources, was used to collect the data. In this case was mainly used so-called "medical tool" Červenodvorská cesta and Zápisy z Apolináře. Next titles were specialized magazines...

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