Hodnocení obsahu fenolických látek v rostlinném materiálu.

Hollá, Marcela

Charles University, Faculty of Pharmacy in Hradec Králové Department of Analytical Chemistry Candidate: Mgr. Marcela Hollá Supervisor: assoc. prof. PharmDr. Hana Sklenářová, Ph.D. Consultant: prof. RNDr. Dalibor Šatínský, Ph.D. Title of Doctoral Thesis: Evaluation of phenolic substances content in plant material Scientific community has always been interested in the research of natural substances. The main reasons are a huge diversity of substances themselves and their significant impact on human health. The development of new analytical and extraction methods, including new approaches for sample preparation, enable obtaining more detailed knowledge about the structure and biological properties of plant substances. A significant group consists of substances with antioxidant effects, such as phenolic compounds, which are an important part of human food. The presented dissertation thesis deals with determination of selected groups of natural substances from the point of view of specific requirements for chromatographic separation, choice of detection technique with regard to the selectivity and sensitivity of the determination, as well as the possibility of applying modern and green extraction approaches. The first part of the presented work is devoted to the issue of determination of selected plant...

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