Original title: MOCVD Iron Oxide Nanoparticle Generation not Only for Follow-Up Inalation Exposure Experiments.
Authors: Moravec, Pavel ; Schwarz, Jaroslav ; Vodička, Petr ; Kupčík, Jaroslav ; Švehla, Jaroslav
Document type: Papers
Conference/Event: Výroční konference České aerosolové společnosti /19./, Piešťany (SK), 20181025
Year: 2018
Language: eng
Abstract: Iron oxide nanoparticles (NPs) are industrially produced and commercially available and they are also frequently emitted into the environment by iron making plants. In the human body, iron is maintained at homeostatic fairly low level. However, freshly generated iron oxide NPs cause febrile and inflammatory response known as metal fume fever, but the potential in vivo consequences of inhalation of iron oxide NPs from the atmosphere has not yet been investigated. An overview of recent studies evaluating iron oxide NPs cytotoxicity, genotoxicity, developmental toxicity and neurotoxicity was presented by Valdiglesias et al. (2015). Toxicity of iron oxide NPs has been studied both in vitro and in vivo. Exposure chamber for the whole body inhalation experiments with small laboratory animals was constructed at the Institute of Analytical Chemistry of the CAS (Večeřa et al., 2011) and some methods of NPs generation for these experiments were already tested in our laboratory (Moravec et al., 2015. Moravec et al., 2016). In this study we tested a method of long lasting generation of iron oxide NPs by pyrolysis and oxidation of ironIII acetylacetonate (FeAA3).
Keywords: exposure studies; iron oxide nanoparticle generation; nanoparticle characterization
Project no.: GBP503/12/G147 (CEP)
Funding provider: GA ČR
Host item entry: Sborník XIX. výroční konference České aerosolové společnosti, pp. 44-47, ISBN 978-80-270-4780-2
Note: Související webová stránka: http://hdl.handle.net/11104/0289067
Rights: This work is protected under the Copyright Act No. 121/2000 Coll.

Institution: Institute of Chemical Process Fundamentals AS ČR (web)
Original record: http://hdl.handle.net/11104/0289067

Permalink: http://www.nusl.cz/ntk/nusl-387709

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Research > Institutes ASCR > Institute of Chemical Process Fundamentals
Conference materials > Papers
 Record created 2018-11-15, last modified 2020-03-27

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