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Original title:
Biventricular pacing optimization by means of the dyssynchrony parameter
Authors: Jurák, Pavel ; Leinveber, P. ; Halámek, Josef ; Plešinger, Filip ; Postránecká, T. ; Lipoldová, J. ; Novák, M.
Document type: Papers
Conference/Event: Computing in Cardiology (CinC) 2016, Vencouver (CA), 20160911
Year: 2016
Language: eng
Abstract: To improve Cardiac Resynchronization Therapy (CRT), different interventricular delay (VVD) settings can be used. However, relatively small VVD induced hemodynamic changes cannot be measured by standard echocardiographic methods. The QRS complex duration (QRSd) is mostly the main criterion. Here we introduce a new dyssynchrony parameter (DYS) that is able to more accurately detect improved electrical synchrony. Methods: 12-lead 5 kHz ECG during 3-10 minute rest period was measured in 46 patients with CRT OFF and CRT ON with VVD 0 ms (CRT0) and -20 ms (CRT20). We detected QRSd and the dyssynchrony parameter DYS as the time difference between 500-1000 Hz averaged envelopes positions in the V1 and V6 leads in the QRS complex region. Results: 32 of 46 patients had a positive CRT response manifested by QRSd shortening and a DYS decrease. 28 of 32 patients had a positive LV pre-excitation effect: additional QRSd shortening of 4.7+/-.9 ms and a DYS decrease of 12.6+/-7.5 ms. The correlation coefficient of QRSd and DYS changes (CRT 0 vs CRT 20) was 0.23 and indicates information diversity. The DYS parameter differs from QRSd and provides a significantly higher response to VVdelay changes (p <; 0.001).
Keywords: cardiology; cathode ray tubes; electrocardiography; hemodynamics; medical treatment; optimization
Project no.: GAP102/12/2034 (CEP), LO1212 (CEP), ED0017/01/01
Funding provider: GA ČR, GA MŠk, GA MŠk
Host item entry: Computing in Cardiology (CinC) 2016, ISBN 978-1-5090-0896-4, ISSN 2325-8861
Institution: Institute of Scientific Instruments AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0271745
Permalink: http://www.nusl.cz/ntk/nusl-373370
The record appears in these collections:
Research > Institutes ASCR > Institute of Scientific Instruments
Conference materials > Papers
Authors: Jurák, Pavel ; Leinveber, P. ; Halámek, Josef ; Plešinger, Filip ; Postránecká, T. ; Lipoldová, J. ; Novák, M.
Document type: Papers
Conference/Event: Computing in Cardiology (CinC) 2016, Vencouver (CA), 20160911
Year: 2016
Language: eng
Abstract: To improve Cardiac Resynchronization Therapy (CRT), different interventricular delay (VVD) settings can be used. However, relatively small VVD induced hemodynamic changes cannot be measured by standard echocardiographic methods. The QRS complex duration (QRSd) is mostly the main criterion. Here we introduce a new dyssynchrony parameter (DYS) that is able to more accurately detect improved electrical synchrony. Methods: 12-lead 5 kHz ECG during 3-10 minute rest period was measured in 46 patients with CRT OFF and CRT ON with VVD 0 ms (CRT0) and -20 ms (CRT20). We detected QRSd and the dyssynchrony parameter DYS as the time difference between 500-1000 Hz averaged envelopes positions in the V1 and V6 leads in the QRS complex region. Results: 32 of 46 patients had a positive CRT response manifested by QRSd shortening and a DYS decrease. 28 of 32 patients had a positive LV pre-excitation effect: additional QRSd shortening of 4.7+/-.9 ms and a DYS decrease of 12.6+/-7.5 ms. The correlation coefficient of QRSd and DYS changes (CRT 0 vs CRT 20) was 0.23 and indicates information diversity. The DYS parameter differs from QRSd and provides a significantly higher response to VVdelay changes (p <; 0.001).
Keywords: cardiology; cathode ray tubes; electrocardiography; hemodynamics; medical treatment; optimization
Project no.: GAP102/12/2034 (CEP), LO1212 (CEP), ED0017/01/01
Funding provider: GA ČR, GA MŠk, GA MŠk
Host item entry: Computing in Cardiology (CinC) 2016, ISBN 978-1-5090-0896-4, ISSN 2325-8861
Institution: Institute of Scientific Instruments AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0271745
Permalink: http://www.nusl.cz/ntk/nusl-373370
The record appears in these collections:
Research > Institutes ASCR > Institute of Scientific Instruments
Conference materials > Papers
Record created 2018-03-09, last modified 2021-11-24