Original title: CE-nESI/MS in electrode-free design: narrowing the separation channel to 5 μm
Authors: Týčová, Anna ; Foret, František
Document type: Papers
Conference/Event: CECE 2016. International Interdisciplinary Meeting on Bioanalysis /13./, Brno (CZ), 20161017
Year: 2016
Language: eng
Abstract: Capillary electrophoresis-nanospray/mass spectrometry (CE-nESI/MS) in electrodefree\narrangement represents a very simple instrumentation for analysis of biomolecules.\nSo far, CE-nESI/MS analyses in this design were limited to 10-75 μm ID of the\nseparation channel. Although the work with narrower dimensions brings several\nchallenges, there is a great potential for better sensitivity, improved separation power\nand lower sample consumption. This work is devoted to some practical aspects of\nexperiments in narrow bore channels and systematic evaluation of CE-nESI/MS\nanalyses conducted in capillaries of 25, 15 and 5 μm ID.
Keywords: CE-nESI/MS; electrode-free arragement
Project no.: GBP206/12/G014 (CEP), GA15-15479S (CEP)
Funding provider: GA ČR, GA ČR
Host item entry: CECE 2016. 13th International Interdisciplinary Meeting on Bioanalysis, ISBN 978-80-904959-4-4

Institution: Institute of Analytical Chemistry AS ČR (web)
Document availability information: Fulltext is available in the digital repository of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0265752

Permalink: http://www.nusl.cz/ntk/nusl-261689


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Research > Institutes ASCR > Institute of Analytical Chemistry
Conference materials > Papers