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Evaluation of pulse wave velocity in the human body
Mezuláníková, Radka ; Viščor,, Ivo (referee) ; Jurák, Pavel (advisor)
This Mater's thesis deals with the evaluation of pulse wave velocity using multi-channel whole-body impedance cardiography. Data were taken from the group of healthy volunteers whose impedance changes were measured during rest, respiratory maneuvers, tilt and stress exercise. The result of this measurement are values of peaks of pulse wave time shifts towards R-wave. The velocity values towards the thorax electrodes were recalculated on the basis of knowledge about the pulse wave time shifts and the distances from the heart to the scanned locations, which were measured using the arterial segment's lengths.
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Blood presure measurement in LabVIEW
Pelikán, Ondřej ; Štohanzlová, Petra (referee) ; Harabiš, Vratislav (advisor)
The main purpose of this semestral project is to design and realize a product that allows to acquire the Korotkoff’s sounds and measure blood pressure by using a computer. The paper gives a proposal of the preamplifier for acquisition of Korotkoff’s sounds, wiring of product and designed software for data acquisition. Document also contains theoretical informations about options of blood pressure measuring.
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Continuous measurement of blood pressure
Kopčil, Petr ; Chmelař, Milan (referee) ; Nováková, Zuzana (advisor)
This paper deals with the physiology of cardiovascular system, explains elementary principles related to blood flow physiology and describes some basic mechanisms for regulation and blood pressure measurement. The paper also includes a description of the medical device, known as the Finometer (FMS, Netherlands), for continuous non-invasive blood pressure measurement and suggests a way to data export from this device to a text file. It introduces user friendly application to manage recorded data written in MATLAB. There is a statistical test to assess the difference between two statistical data files in the last chapter of this paper which includes a comparison our results with studies made in Czech Republic and other countries too.
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Blood presure measurement in LabVIEW
Čermák, Marek ; Sekora, Jiří (referee) ; Harabiš, Vratislav (advisor)
The aim of this work is to design and create a product for automated measurement of blood pressure by auscultatory method by using a computer. Thesis contains a description of the blood pressure, also there are explained ways of its monitoring, basic rules for its measurement and the methods by which it is possible to measure blood pressure. In the practical part is described measuring system serving to measuring blood pressure by auscultatory method using a computer. There is also shown a design and realization of microphone preamplifier. The work also includes a description of a computer program created in LabVIEW, which is used to measure by using a previously described system. In the end is evaluated the accuracy of the whole meter.
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Measurement of blood pressure and influence of physical load
Vymazal, Bronislav ; Chmelař, Milan (referee) ; Kolářová, Jana (advisor)
Bachelor's thesis is focused on influence assessment of physical load on systolic and diastolic blood pressure. It is analyzed cardiovascular system of human being and an influence of his function on blood pressure. There are mentioned methods of blood pressure monitoring, their physical principle, advantages and disadvantages in the text. The author suggested measuring protocol and methods of statistical processing and evaluation of results.
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Analysis of pulse wave velocity variability
Benešová, Lenka ; Kozumplík, Jiří (referee) ; Svačinová, Jana (advisor)
This diploma thesis deals with the variability of pulse wave velocity. It studies the variability of cardiovascular signals. It presents the research of measurement of pulse wave velocity and its analysis in physiology and pathological physiology. Applies spectral analysis in Matlab to a data set. It evaluates and reviews the results of this analysis
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Study of the mechanisms of action of phenolic compounds on vascular smooth muscle
Alves Dias, Patrícia Alexandra ; Mladěnka, Přemysl (advisor) ; Kyselovič, Ján (referee) ; Štengl, Milan (referee)
Charles University, Faculty of Pharmacy in Hradec Králové Training Workplace Department of Pharmacology and Toxicology Doctoral Degree Program Pharmacology and Toxicology Candidate Patrícia Alexandra Alves Dias, M.Sc. Supervisor prof. Přemysl Mladěnka, Pharm.D., Ph.D. Advisor assoc. prof. Jana Pourová, Pharm.D., Ph.D. Title of Doctoral Thesis Study of the mechanisms of action of phenolic compounds on the vascular smooth muscle Cardiovascular diseases including hypertension, coronary artery disease, peripheral artery disease, and cerebrovascular disease remain the leading cause of death worldwide. In addition, discouraging estimations have suggested a future increase in the number of cardiovascular patients. Thus, novel treatment modalities are clearly needed to prevent or reverse these epidemic trends. Phenolic compounds contain one or more hydroxyl groups bound to a benzene ring. This class of chemicals includes: a) natural compounds (e.g., dietary polyphenols and small phenolic metabolites) referred to as nutraceuticals due to their claimed health-promoting effects and b) synthetic compounds (e.g., bisphenols) which, on the contrary, have been suggested to negatively affect human health. Even if there are claims that polyphenol-rich diet is associated with cardioprotective effects, important...
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Vývoj zařízení pro neinvazivní měření krevního tlaku
Kubošková, Terezie ; Augustynek, Martin
Tento článek se zabývá měřením hypertenze, která má vliv na zdraví jedinců. Hypertenze je spojena se zvýšeným rizikem vzniku srdečních onemocnění a náhlé smrti. Cílem práce je vytvořit funkční tlakoměr pro měření krevního tlaku, se zaměřením na snímaní středního krevního tlaku, v ambulantním prostředí. Pro tento účel byl použit měřící modul OEM NIBP 2020 UP. S pomocí tohoto modulu bylo vytvořeno zařízení pro neinvazivní měření krevního tlaku. Pro usnadnění ovládání a sběr dat byla také vytvořena webová aplikace, která umožňuje zadávání anonymních informací o pacientech a zaznamenávání naměřených hodnot tlaku. Komunikace webu s tlakoměrem je zajištěna pomocí technologie Web Serial API. Výsledkem práce je funkční tlakoměr a webová aplikace pro sběr dat z měření krevního tlaku, které jsou připraveny pro budoucí výzkum.
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Therapy of arterial hypertension in prehospital emergency care and at urgent admission
SYNKOVÁ, Kateřina
The bachelor thesis on the topic of Therapy of arterial hypertension in prehospital emergency care and in the emergency room is focused on dealing with states in cases of sudden escalation of patient's blood pressure. The thesis is divided into a theoretical part and a practical part. In the theoretical part, blood pressure is characterized, including the methods of its measurement, arterial hypertension and hypertensive crisis. Furthermore, there are descriptions of the basic classes of anti-hypertensives and their use in specific groups with arterial hypertension. In the practical part of the bachelor thesis, three goals were set. The first goal was to map out how arterial hypertension is treated in prehospital emergency care within the competences of paramedics and guidelines of given workplace of the emergency medical service. Second goal was to map out the way in which arterial hypertension is treated in emergency rooms of given workplaces, and the third goal was to find out what are the differences between therapy of arterial hypertension in prehospital emergency care and in the emergency room. The research study was carried out via qualitative method of data collection using semi-structured interviews. The interviews were conducted with paramedics operating within the Emergency medical services of the South Bohemia region in the districts of Písek, Tábor and Český Krumlov. In addition, selected paramedics working in the emergency department of České Budějovice Hospital also took part in the interviews. From the results of the research part of the bachelor thesis can be concluded, that the interviewed paramedics have enough experiences and knowledge in the area of treating a patient with arterial hypertension and know when it is adequate to reach out to a medical professional about possible therapy.
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