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Economic and Financial Evaluation of Investment Project
Tomanová, Tereza ; Srba,, Martin (referee) ; Hromádka, Vít (advisor)
This bachelor thesis deals with Economic and Financial Evaluation of Public Investment Project. In theoretical part is described characteristic of Public Investment Project and its life cycle. Subsequently, the thesis deals with the methods of evaluation of public projects and describes in more detail the Cost Benefit Analysis, which is further used in the case study. The practical part of the thesis focuses on the processing of economic and financial analysis. The evaluated investment project is the construction of a new cycle path between the town named Hodonín and the village Ratíškovice.
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Reservoirs - Brno, Zluty kopec (Yellow hill)
Tomanová, Tereza ; Horňasová, Tereza (referee) ; Nový, Vítězslav (advisor)
The diploma thesis deals with the possible use of now defunct reservoirs on the Yellow Hill. This water supply complex consists of three underground reservoirs and a technical house. The area is spread over a large plot of land overgrown with wild vegetation in the middle of a residential area. The set of underground reservoirs, covered by a system of arches supported by pillars, represents a unique architectural and technical monument. The aim of the proposal is to make the reservoir area accessible to the public through new functions while preserving their historical value. The main motive of the concept is an interactive water museum built in the youngest reinforced concrete reservoir. The exhibition deals, among other things, with a very current topic of sustainable water management. The complex is complemented by a new visitor center, which will make it possible to access the reservoirs through a new entrance to the underground. The existing unmaintained area of greenery will be transformed into a public park independent of the operation of reservoirs.
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Economy of Brownfield Revitalization from the Perspective of the City and the Investor
Tomanová, Tereza ; Růžička, Jan (referee) ; Hromádka, Vít (advisor)
The diploma thesis is focused on determining the cash flow of the investment project and evaluating the economic efficiency of the Nová Zbrojovka brownfield revitalization development project. Development projects, economic analysis and sensitivity analysis are described in the theoretical part. Both of these analyzes are subsequently used in the practical part of the thesis. Furthermore, the work deals in detail with the issue of brownfields, describes possible methods of revitalization and other Brownfields in the territory of the city of Brno. The practical part of the diploma thesis describes the implemented project in detail, determines the cash flow of the project and performs an economic and sensitivity analysis of the investment project.
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Analysis of antibody response during BK virus infection
Tomanová, Tereza ; Španielová, Hana (advisor) ; Saláková, Martina (referee)
BK virus is a human polyomavirus which is highly prevalent in the population. The virus is usually not very dangerous to its host, but it may cause complicati- ons in immunosuppressed patients. These complications commonly appear after kidney transplantation because BK virus persists in kidney epithelial cells. There are four subtypes of BK virus and it might be clinically important to screen for the identity of subtypes in matched pairs of donors and recipients of the kidney. This determination of the subtype specific antibodies by simple test could help to manage complications after the surgery. During previous project the ELISA test that could serologically differentiate between two main BK virus subtypes (I and IV) was designed, but its development is complicated by the fact that there is a strong cross-reactivity between the BK virus subtypes and antibodies. The modification of antigen towards better specificity might be required to succeed. Consequently, the main aim of this diploma thesis was to map important spots of major capsid protein VP1 of BK virus, particulary in EF and DE loops, which could participate in binding of antibodies. This aim was addressed by targeted mutagenesis of the gene coding VP1 protein in the region of the respective loop. Nucleotides coding two surface aminoacids...
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Reservoirs - Brno, Zluty kopec (Yellow hill)
Tomanová, Tereza ; Horňasová, Tereza (referee) ; Nový, Vítězslav (advisor)
The diploma thesis deals with the possible use of now defunct reservoirs on the Yellow Hill. This water supply complex consists of three underground reservoirs and a technical house. The area is spread over a large plot of land overgrown with wild vegetation in the middle of a residential area. The set of underground reservoirs, covered by a system of arches supported by pillars, represents a unique architectural and technical monument. The aim of the proposal is to make the reservoir area accessible to the public through new functions while preserving their historical value. The main motive of the concept is an interactive water museum built in the youngest reinforced concrete reservoir. The exhibition deals, among other things, with a very current topic of sustainable water management. The complex is complemented by a new visitor center, which will make it possible to access the reservoirs through a new entrance to the underground. The existing unmaintained area of greenery will be transformed into a public park independent of the operation of reservoirs.
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|
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Economic and Financial Evaluation of Investment Project
Tomanová, Tereza ; Srba,, Martin (referee) ; Hromádka, Vít (advisor)
This bachelor thesis deals with Economic and Financial Evaluation of Public Investment Project. In theoretical part is described characteristic of Public Investment Project and its life cycle. Subsequently, the thesis deals with the methods of evaluation of public projects and describes in more detail the Cost Benefit Analysis, which is further used in the case study. The practical part of the thesis focuses on the processing of economic and financial analysis. The evaluated investment project is the construction of a new cycle path between the town named Hodonín and the village Ratíškovice.
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|
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Analysis of antibody response during BK virus infection
Tomanová, Tereza ; Španielová, Hana (advisor) ; Saláková, Martina (referee)
BK virus is a human polyomavirus which is highly prevalent in the population. The virus is usually not very dangerous to its host, but it may cause complicati- ons in immunosuppressed patients. These complications commonly appear after kidney transplantation because BK virus persists in kidney epithelial cells. There are four subtypes of BK virus and it might be clinically important to screen for the identity of subtypes in matched pairs of donors and recipients of the kidney. This determination of the subtype specific antibodies by simple test could help to manage complications after the surgery. During previous project the ELISA test that could serologically differentiate between two main BK virus subtypes (I and IV) was designed, but its development is complicated by the fact that there is a strong cross-reactivity between the BK virus subtypes and antibodies. The modification of antigen towards better specificity might be required to succeed. Consequently, the main aim of this diploma thesis was to map important spots of major capsid protein VP1 of BK virus, particulary in EF and DE loops, which could participate in binding of antibodies. This aim was addressed by targeted mutagenesis of the gene coding VP1 protein in the region of the respective loop. Nucleotides coding two surface aminoacids...
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Analysis of Accounting Solution of Selected National Mergers of Business Corporations
Tomanová, Tereza ; Vomáčková, Hana (advisor) ; Pospíšil, Jiří (referee)
This diploma thesis is focused on mergers of business corporations carried out in the Czech Republic in 2015. The number of carried out mergers reached 466 according to the analysis performed in this thesis. The theoretical chapters deal with Czech business, accounting and tax law regulation of mergers. The core of 5th chapter of this thesis consists of analysis of all carried out mergers and it is supplemented by the evaluation of transactions carried out between 2010 and 2015, which proves the increasing trend in the number of mergers. Second practical chapter analyses the accounting solution of each merger on the sample of national mergers of 2015.
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