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Phlebotomine saliva: the perspecives of application of some of their recombinantly produced proteins
Rožníčková, Lucie ; Zídková, Lenka (advisor) ; Štáfková, Jitka (referee)
Sandflies (Diptera: Phlebotominae) are the vectors of one of the most significant tropical diseases, leishmaniosis. Their saliva contains substances with antihemostatic, vasodilatory and immunomodulatory effect. These substances are of great significance in transmission of leishmaniosis, because of their ability to influence the host immune response. Naive host saliva modulate the immune system to such an extent, that it reduces an infective dose and increases the pathogenicity of leishmaniosis. On the other hand, a repeatedly exposed host generates a cellular and antibody immune response, which is able to make the initial development of infection impossible. Repeated exposure of individual sandflies lead to formation of antibodies against components of saliva, which may play a role as a rate exposure indicator and thus the risk of leashmaniosis infection. These proteins and glycoproteins can be produced by recombinant DNA technology. Recombinant vaccine could help in the fight against leishmaniasis. Keywords: saliva, sand fly, leishmania, recombinant proteins.
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Position of nuclear energy in Europe (focus on France)
Rožníčková, Lucie ; Kašpar, Václav (advisor) ; Vošta, Milan (referee)
The objective of the thesis is to characterize the nuclear energy in the european area with the focus on nuclear energy in France. The sector of nuclear energy is now experiencing a new period, so-called "nuclear renaissance". Many european countries decided to rebuild the present nuclear power sites or to construct new ones. Nuclear energy is the most advantageous solutions for many european countries because it decreases external energy dependence and it helps to diminish the carbon dioxide emissions. In the connection with the Czech Presidency in the European Union, it was made proposal for the "Nuclear Security Community" which has to unify the security level of member states of the EU and to intensify the mutual cooperation in the domain of nuclear energy. France represents world nuclear leader thanks to efficiently operating oragnizations, excellent results in nuclear research, realization of nuclear fuel recycling and strong government support. Nucler energy in France can serve as an example for four recommendations to other european countries: government support, efficiently working research institutions, global cooperation between all subjects participating on the formation of nuclear energy and active involvement in the international cooperation in nuclear energy. In spite of constantly high initial investment in construction of nuclear power sites, the nuclear energy seems to experience a positive future.
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Postavení Evropské unie ve světovém obchodu v letech 1995-2007
Rožníčková, Lucie ; Novotná, Zuzana (advisor) ; Hitzgerová, Vlasta (referee)
Bakalářská práce charakterizuje postavení Evropské unie ve světovém obchodu v letech 1995-2007. První část se zaměřuje na současné postavení Evropské unie ve světovém obchodu z hlediska obchodu vnitřního a vnějšího. Druhá část se týká postavení Evropské unie ve světovém obchodu před největším rozšíření a soustředí se na obchodní vztahy a konkurenceschopnost. Třetí část zkoumá změny v postavení Evropské unie ve světovém obchodu po největším rozšíření.
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