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Home 60+
Oravcová, Martina ; Gregor, Karol (referee) ; Mléčka, Jan (advisor)
Home should be a place where I live, where I feel safe, where I have privacy, where I can always return and like to return. It is my refuge from which I go out into the world every day. At home, I will find comfort, warmth, love, respect, understanding ... Having a home has been one of the basic needs of every human being since the beginning of humanity. It is possible to lead a full life only if it is fulfilled not only but also of this need. The analytical part of the work deals with the possibilities, needs and requirements of people for housing from the age of 60 and their application in architecture. The design of a residential building not only for seniors in the facility is part of the practical part. Combining several generations and functions in one place supports the creation of interpersonal relationships and the integration of seniors into society. In the building, there is a facility for the elderly connected with daycare for seniors, a dining room and a pensioners' club in connection with general rental flats for young families. The project is proposed for the municipality of Važec, located in the district of Liptovský Mikuláš in Slovakia.
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Funkcia a vplyv moderných nástrojov propagácie pri oslovování klientov cestovného ruchu
Oravcová, Martina
Bachelor thesis deals with the function and influence of modern communication tools in reaching out to clients of tourism. The main goal of this work is to research, identify and promotion of use of modern tools among providers of touristic services. The work includes a reconciliation of the benefits and use of modern tools among providers and customers. For this purpose it was used a primary questionnaire survey.
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Transcription factors CSL and their role in the yeast Schizosaccharomyces pombe
Oravcová, Martina ; Převorovský, Martin (advisor) ; Heidingsfeld, Olga (referee) ; Krásný, Libor (referee)
Proteins of the CSL family (CBF1/RBP-Jκ/Suppressor of Hairless/LAG-1) act as effectors of the Notch signalling pathway in metazoan organisms. They function as repressors or activators of gene transcription in the framework of this pathway and influence many developmental processes. Metazoan CSL proteins can regulate gene expression Notch-independently as well. Notch-independent functions of CSL proteins might be evolutionarily ancestral and in cells and organisms may be important equally as Notch-dependent functions. Presence of CSL proteins was identified in several fungal species, organisms lacking the Notch signalling pathway components and most of known metazoan interacting partners of CSL proteins. CSL paralogs of the fission yeast Schizosaccharomyces pombe, cbf11 and cbf12, are non-essential genes encoding proteins localized in the nucleus of the cell. They exert antagonistic effects on regulation of processes like coordination of nuclear and cellular division and cell cycle progression, ploidy maintenance, cell adhesion and other. In this study, we have proved that both CSL paralogs are able to sequence-specifically bind the CSL-response element DNA in vitro and Cbf11 in vivo as well. Both proteins could activate gene expression in vivo and perform the function of transcription factors....
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Transcription factors CSL and their role in the yeast Schizosaccharomyces pombe
Oravcová, Martina
Proteins of the CSL family (CBF1/RBP-Jκ/Suppressor of Hairless/LAG-1) act as effectors of the Notch signalling pathway in metazoan organisms. They function as repressors or activators of gene transcription in the framework of this pathway and influence many developmental processes. Metazoan CSL proteins can regulate gene expression Notch-independently as well. Notch-independent functions of CSL proteins might be evolutionarily ancestral and in cells and organisms may be important equally as Notch-dependent functions. Presence of CSL proteins was identified in several fungal species, organisms lacking the Notch signalling pathway components and most of known metazoan interacting partners of CSL proteins. CSL paralogs of the fission yeast Schizosaccharomyces pombe, cbf11 and cbf12, are non-essential genes encoding proteins localized in the nucleus of the cell. They exert antagonistic effects on regulation of processes like coordination of nuclear and cellular division and cell cycle progression, ploidy maintenance, cell adhesion and other. In this study, we have proved that both CSL paralogs are able to sequence-specifically bind the CSL-response element DNA in vitro and Cbf11 in vivo as well. Both proteins could activate gene expression in vivo and perform the function of transcription factors....
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Home 60+
Oravcová, Martina ; Gregor, Karol (referee) ; Mléčka, Jan (advisor)
Home should be a place where I live, where I feel safe, where I have privacy, where I can always return and like to return. It is my refuge from which I go out into the world every day. At home, I will find comfort, warmth, love, respect, understanding ... Having a home has been one of the basic needs of every human being since the beginning of humanity. It is possible to lead a full life only if it is fulfilled not only but also of this need. The analytical part of the work deals with the possibilities, needs and requirements of people for housing from the age of 60 and their application in architecture. The design of a residential building not only for seniors in the facility is part of the practical part. Combining several generations and functions in one place supports the creation of interpersonal relationships and the integration of seniors into society. In the building, there is a facility for the elderly connected with daycare for seniors, a dining room and a pensioners' club in connection with general rental flats for young families. The project is proposed for the municipality of Važec, located in the district of Liptovský Mikuláš in Slovakia.
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Transcription factors CSL and their role in the yeast Schizosaccharomyces pombe
Oravcová, Martina ; Převorovský, Martin (advisor) ; Heidingsfeld, Olga (referee) ; Krásný, Libor (referee)
Proteins of the CSL family (CBF1/RBP-Jκ/Suppressor of Hairless/LAG-1) act as effectors of the Notch signalling pathway in metazoan organisms. They function as repressors or activators of gene transcription in the framework of this pathway and influence many developmental processes. Metazoan CSL proteins can regulate gene expression Notch-independently as well. Notch-independent functions of CSL proteins might be evolutionarily ancestral and in cells and organisms may be important equally as Notch-dependent functions. Presence of CSL proteins was identified in several fungal species, organisms lacking the Notch signalling pathway components and most of known metazoan interacting partners of CSL proteins. CSL paralogs of the fission yeast Schizosaccharomyces pombe, cbf11 and cbf12, are non-essential genes encoding proteins localized in the nucleus of the cell. They exert antagonistic effects on regulation of processes like coordination of nuclear and cellular division and cell cycle progression, ploidy maintenance, cell adhesion and other. In this study, we have proved that both CSL paralogs are able to sequence-specifically bind the CSL-response element DNA in vitro and Cbf11 in vivo as well. Both proteins could activate gene expression in vivo and perform the function of transcription factors....
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Transcription factors CSL and their role in the yeast Schizosaccharomyces pombe
Oravcová, Martina
Proteins of the CSL family (CBF1/RBP-Jκ/Suppressor of Hairless/LAG-1) act as effectors of the Notch signalling pathway in metazoan organisms. They function as repressors or activators of gene transcription in the framework of this pathway and influence many developmental processes. Metazoan CSL proteins can regulate gene expression Notch-independently as well. Notch-independent functions of CSL proteins might be evolutionarily ancestral and in cells and organisms may be important equally as Notch-dependent functions. Presence of CSL proteins was identified in several fungal species, organisms lacking the Notch signalling pathway components and most of known metazoan interacting partners of CSL proteins. CSL paralogs of the fission yeast Schizosaccharomyces pombe, cbf11 and cbf12, are non-essential genes encoding proteins localized in the nucleus of the cell. They exert antagonistic effects on regulation of processes like coordination of nuclear and cellular division and cell cycle progression, ploidy maintenance, cell adhesion and other. In this study, we have proved that both CSL paralogs are able to sequence-specifically bind the CSL-response element DNA in vitro and Cbf11 in vivo as well. Both proteins could activate gene expression in vivo and perform the function of transcription factors....
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Europeanisation of Criminal Law
Oravcová, Martina ; Herczeg, Jiří (advisor) ; Gřivna, Tomáš (referee)
Europeanisation of Criminal Law Summary Throught the use of common adaptation of the basic principles of criminal law in the european dimension there is a possibility to remove an opacity and inefficiency of individual national and international instruments of criminal law so far. This effort can be the best observed in the procedures of the European Community or European Union. It should all happen by harmonizing laws and strengthening cooperation between the European Union member states. Integration of criminal law is pointed to be done in three main directions. First, it affects substantive criminal law by harmonizing particular merits of criminal offences. Second, it already affected criminal procedure by achieving mutual recognition of judicial decisions. The third way of integration is the institutional framework for judicial cooperation in criminal matters, followed-up by institutions of criminal cooperation. Criminal law as a public law is closely related to the state sovereignty. This fact, even today, suspends the opportunity to create sort of unified system of transnational criminal law within the European Union. Moreover, the very concept of criminal law is not clearly established in European law as it is in Czech law. For example, it includes even different illegal dealings than regular...
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Funkcia a vplyv moderných nástrojov propagácie pri oslovování klientov cestovného ruchu
Oravcová, Martina
Bachelor thesis deals with the function and influence of modern communication tools in reaching out to clients of tourism. The main goal of this work is to research, identify and promotion of use of modern tools among providers of touristic services. The work includes a reconciliation of the benefits and use of modern tools among providers and customers. For this purpose it was used a primary questionnaire survey.
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