|
|
Application of novel genomic techniques in studies of pathogenesis of selected rare inherited disorders
Nosková, Lenka ; Kmoch, Stanislav (advisor) ; Sedláček, Zdeněk (referee) ; Živný, Jan (referee)
Rare diseases are a heterogeneous group of disorders. Knowledge of their molecular basis is poor and till recently there were no appropriate methodical approaches due to a limited number of patients. Novel genomic techniques, especially the DNA array technology and the next generation sequencing emerging in last few years, enabled studies of these diseases even in small families and sporadic cases. This PhD thesis focuses on application of novel genomic techniques in studies of rare inherited diseases. It describes a use of DNA array technology in linkage analysis, analysis of differential gene expression, analysis of copy number variations and homozygous mapping, and a use of next generation sequencing technology. Combination of these methods was used for identification of molecular basis of adult neuronal ceroid lipofuscinosis, Rotor syndrome, isolated defect of ATP synthase and mucopolysaccharidosis type IIIC.
|
|
|
Level of Legal Knowing of Managers at School and at Educational Institutions
Smutný, Lukáš ; Kitzberger, Jindřich (advisor) ; Nosková, Lenka (referee)
TITLE: Level of Legal Knowing of Managers at School and et Educational Institutions AUTHOR: Ing. Lukáš Smutný DEPARTMENT: Education Management Centre SUPERVISOR: RNDr. Jindřich Kitzberger ABSTRACT: Bachelor thesis on The Level of Legal Knowing of Managers at School and at Educational Institutions is concerning with knowledge level of legal knowing of headmasters of school and educational institutions as managers in education, analyzes, evaluates and summarizes certain basis as "legal standard of managers". The theoretical part summarizes basic teoretical information, from which proceeds the practical part of thesis, its target results in the researched issues of two basic hypothesis if small primary schools are comparable with level of legal mind of their managers to bigger schools and after if level of legal mind of school managers is quantitative reflection of the number of completed educational courses in legislation within the system of next education for pedagogical staff. The practical part represents results from questionnaire survey, research, anonymous tests with the form of closed questions focusing on the aplication of legislation. KEYWORDS: level; law; legal mind; headmaster; small schools; bigger schools; next education for pedagogical staff
|
|
|
Role of director of a kindergarten in shaping school culture
Seidlová, Marie ; Voda, Jan (advisor) ; Nosková, Lenka (referee)
Thesis deals with the role of the director of a kindergarten within shaping of the school culture and with the potential of school culture in terms of contemporary education. Thesis focuses on the factors which the director influences the most and which leads to increased level of quality of teachers' work. In the theoretical part the emphasis is on understanding the concepts in the school culture, school climate, management and leadership and also on relationships in kindergarten, which create and develop a quality society. Further, the thesis concerns the research investigation, which detects the orientation of the issue of school culture and current use of knowledge in connection to the management of kindergarten. Key words Kindergarten surrounding, communication, kindergarten culture, interpersonal relationships, labor relations, director, employee satisfaction, styles of management.
|
|
| |
|
| |
|
|
Marketing strategy of the village primary school management within the competitive background created by the town primary schools
Šulcová, Karin ; Svoboda, Petr (advisor) ; Nosková, Lenka (referee)
The final thesis focuses on evaluating the marketing strategies of the village primary school management within the competitive background created by the town primary schools. One of the main points of the thesis is to enrich these strategies by means of executive directors' as well as my own experience. Other sources of such enrichment are the study literature and the available research knowledge as well as the knowledge of the chief pedagogical executives' final theses. In this respect, the marketing strategies should be posing a benefit for a classical village primary school to stand up to the challenging competitive struggle. The benefit from the thesis consists in using its conclusions by the village school headmasters as well as the institutors.
|
|
| |
|
| |
|
| |
|
|
Financial Analysis of the Direct Costs of Selected Educational Facilities Established by the ÚSC in Individual Regions Funded from the State Budget
Kapsiová, Ivana ; Marková, Jana (advisor) ; Nosková, Lenka (referee)
Solving the issues of financing is an integral part of every managerial work. For the most accurate finding how to deal with the given situation, developing of complex analyzes is necessary. In the area of education, these analyzes are performed at different stages of the education system, but the area of non-teaching staff, school meals workers in particular, is slightly neglected. Therefore, I believe that an analysis of financing the direct costs of selected school facilities established by the ÚSC in each region may be an example of how the direct costs are developing. In this way, employees of those regions will get a comprehensive view of the issue of direct costs on school catering facilities. The result should be an indication of the steps that will help to solve the issue of financing the direct costs and that will show other forms of additional financing in this are
|
guest ::
RSS feed.