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Cultural activitis in the City Domažlice
Macháčková, Tereza ; Pokorný, Jiří (advisor) ; Hnilica, Jiří (referee)
This written work deals with cultural activities of the inhabitants of the town Domažlice between the years 1880 - 1899. The used information is taken from the "Posel od Čerchova" newspaper. The aim of the work is to show particular cultural events as they were presented in the newspaper. The work is divided into three chapters. The first chapter is focused on the concept of culture. It explains the importance of the word culture and events that happened in the 19th century, especially in the second half of the 19th century. The middle part introduces us into the history of Domažlice in the 19th century. We want to create at least a minimal concept of the city development and of the form of the city. We describe the political and economic level of the city in the defined years. We include institutions which were there.The last part shows the cultural activities of the inhabitants the way they were presented in the local newspapers. We answer the question how people lived in a small town and what cultural life they had. We got some answers. The most common activity was the formation of clubs that allowed people to take part in some private or public social events like concerts, trips, lectures, debates etc. The membership brought certain benefits and a certain self-fulfilment. We learnt about the...
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Expression of WT1 and its splicing variants in myeloid leukemias
Macháčková Lopotová, Tereza
3 Abstract Myeloid leukemias include malignant diseases characterized by clonal expansion of the myeloid cell lineage. While in case of chronic myeloid leukemia (CML), the main cause of the disease has already been identified - t(9;22) and the aktivity of the fusion product of the translocation BCR-ABL, acute myeloid leukemia (AML) has been associated with plenty of different translocations and mutations. The aim of this work was to contribute to the improvement of monitoring of patients with myeloid leukemias via detailed study of the panleukemic marker Wilms tumor gene 1 (wt1) expression. Prognostic value of wt1 expression has been proved for AML patients, however, it has not yet been confirmed for CML patients. Expression of different wt1 variants (more then 36 protein products) is known very poorly in both, AML and CML as well as in normal hematopoiesis. Most of the study is focused on CML, only limited parts are dedicated to AML. In the first part of the work, we clearly proved prognostic value of total wt1 mRNA expression for CML patients. Statistical evaluations revealed critical wt1 values which enable to specify prognosis of patients responding non-optimally to imatinib. Bcr-abl looses much of its prognostic value in these patients. Further, we have designed and optimized PCRs for selected wt1...
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Imigrační politika Velké Británie a její specifika v rámci Evropské unie
Macháčková, Tereza
This diploma thesis deals with the topic of United Kingdom´s immigration policy and its specifics with regards to the European Union. This thesis focuses on what is the impact of the political decisions on immigration flow. It also looks at the specific relationship of United Kingdom and European Union when it comes to immigration policy. This thesis starts with the theoretical framework. Historical overview of British immigration policy follows. Then this thesis should also contribute to mapping of actual and current immigration policy in the United Kingdom. At the same time this thesis focuses on the current direction of immigration flow, motivation factors of the immigrants and how does the immigration in UK impact the current policies or even the public opinion. It also looks on the importance of the immigration topic from Brexit perspective. This thesis explores the changes in British immigration policy and the current restrictive direction.
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The usage of virtual reality in therapy of patients with neglect syndrome with consideration of a cybersickness risk
Macháčková, Tereza ; Pánek, David (advisor) ; Pavlů, Dagmar (referee)
Title: The usage of virtual reality in therapy of patients with neglect syndrome with consideration of a cybersickness risk. Objective: To find out if stroke patients with neglect syndrome tend to have higher risk of gaining cybersickness after using virtual reality compared to stroke patients without neglect syndrome and healthy population. Also, to find out if the severity of neglect syndrome has correlation with the severity of gained cybersickness. Afterwards to evaluate the trend of making games in virtual reality for treating neglect syndrome with consideration of a cybersickness risk. Methods: The experiment participants played game in virtual reality developed for treating neglect syndrome for ten minutes. During the game participants were seated and were playing using head movements. A HTC VIVE console was used to deliver the virtual reality game. Participants were divided into 3 groups: the group Zdraví (n = 12) without neurological impairment, the group CMP (n = 6) for stroke patients without neglect syndrome and the group Neglect (n = 10) for stroke patients with neglect syndrome (KF-NAP ≥ 1). Each proband had to fill Sickness Simulator Questionnaire which was used to detect cybersickness before and after playing the game in virtual reality. Collecting and sorting of the data was done...
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Case Study of Physical therapy management of a patient with systemic scleroderma
Macháčková, Tereza ; Maršáková, Kateřina (advisor) ; Zinková, Iva (referee)
Title Case study of physical therapy management of a patient with systemic scleroderma Summary The topic of this work is progressive disease called Systemic scleroderma. For this disease are typical fibrotic changes in connective tissue such as are in skin and in some organs. The first part of the work summarizes information about this disease. The second part of this work contains case study of physical management of a patient with this diagnosis. The case study includes initial examination, suggestion of therapies and implementation. After this part is a final examination. At the end of the second part is an evaluation of performed therapies. Results At the end of therapies there was an improvement in patient's health. Key words Systemic scleroderma, rheumatic diseases, physical therapy, case study
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Expression of WT1 and its splicing variants in myeloid leukemias
Macháčková Lopotová, Tereza
3 Abstract Myeloid leukemias include malignant diseases characterized by clonal expansion of the myeloid cell lineage. While in case of chronic myeloid leukemia (CML), the main cause of the disease has already been identified - t(9;22) and the aktivity of the fusion product of the translocation BCR-ABL, acute myeloid leukemia (AML) has been associated with plenty of different translocations and mutations. The aim of this work was to contribute to the improvement of monitoring of patients with myeloid leukemias via detailed study of the panleukemic marker Wilms tumor gene 1 (wt1) expression. Prognostic value of wt1 expression has been proved for AML patients, however, it has not yet been confirmed for CML patients. Expression of different wt1 variants (more then 36 protein products) is known very poorly in both, AML and CML as well as in normal hematopoiesis. Most of the study is focused on CML, only limited parts are dedicated to AML. In the first part of the work, we clearly proved prognostic value of total wt1 mRNA expression for CML patients. Statistical evaluations revealed critical wt1 values which enable to specify prognosis of patients responding non-optimally to imatinib. Bcr-abl looses much of its prognostic value in these patients. Further, we have designed and optimized PCRs for selected wt1...
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Domažlice in the times of Petr Hana
Macháčková, Tereza ; Pokorný, Jiří (advisor) ; Foltýn, Dušan (referee)
This master thesis deals with history of the city Domažlice in the times of Petr Hana. It means from 1861 to 1905 when he permanently resided there. The thesis is divided into two chapters. The first one is devoted to the period up to 1889 when Petr Hana became a burgomaster. The second one is devoted to the period when he became a mayor. Both parts deal with the political, economic, cultural and social events and point to connection with activities of Petr Hana. It shows importance of this man in their connection with a development of the city and his share on events which took place in the defined period. Specifically in both chapters, I examine elecetions, a governance and city management, unions and their activities, a development of education, an economy and an industry, city institutions and different projects. I try to reveal the character of this period from gathered information. The main sources are, in addition to archival resources available in the Archival of Muzeum of Chodsko and the State Regional Archive in Domažlice, period copies of the local newspaper "Posel od Čerchova" and "Domažlické listy" which enable to capture the atmosphere of the period in this thesis the best.
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Cultural activitis in the City Domažlice
Macháčková, Tereza ; Pokorný, Jiří (advisor) ; Hnilica, Jiří (referee)
This written work deals with cultural activities of the inhabitants of the town Domažlice between the years 1880 - 1899. The used information is taken from the "Posel od Čerchova" newspaper. The aim of the work is to show particular cultural events as they were presented in the newspaper. The work is divided into three chapters. The first chapter is focused on the concept of culture. It explains the importance of the word culture and events that happened in the 19th century, especially in the second half of the 19th century. The middle part introduces us into the history of Domažlice in the 19th century. We want to create at least a minimal concept of the city development and of the form of the city. We describe the political and economic level of the city in the defined years. We include institutions which were there.The last part shows the cultural activities of the inhabitants the way they were presented in the local newspapers. We answer the question how people lived in a small town and what cultural life they had. We got some answers. The most common activity was the formation of clubs that allowed people to take part in some private or public social events like concerts, trips, lectures, debates etc. The membership brought certain benefits and a certain self-fulfilment. We learnt about the...
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Transformation of CTU libraries' collection: Library of Congress Classification implementation
Macháčková, Tereza ; Landová, Hana (advisor) ; Machytková, Marta (referee)
Diplomová práce se zabývá transformací knihovních fondů ČVUT, která je nezbytným předpokladem pro stěhování fondů knihoven ČVUT do Národní technické knihovny (NTK). Velká část knihovních fondů bude v NTK zpřístupněna volně a stavěna podle Třídění Kongresové knihovny (LCC). Cílem práce je popsat implementaci LCC v podmínkách knihoven ČVUT. V první části jsou představeny knihovny ČVUT a projekt NTK. V další části je podrobně analyzován fond knihoven ČVUT. Analýza se týká zejména skladby fondů podle typu dokumentů a podle obsahového hlediska. Hlavní těžiště práce spočívá v představení LCC a jeho implementaci v knihovnách ČVUT. Proces implementace LCC se zabývá především lidskými zdroji, metodikou práce s LCC a softwarovou podporou celého procesu.
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Možnosti uplatnění konceptu komunitního turismu pro zlepšení socioekonomické situace vybrané komunity v Peru
Macháčková ., Tereza
Macháčková T. The possibilities of utilizing the concept of community-based tourism to im-prove the socio-economic situation of selected community in Peru. Bachelor thesis. Mendel University in Brno, 2014. This bachelor thesis deals with the topic of possible usage of the concept "Community-based tourism" in the selected community Llaqquepata in Peru as the option for improving their socio-economic situation and the living standards. This the-sis concludes with the specific developing proposals for implementation of the concept of community-based tourism with regards to real conditions and the nature of the se-lected community. Implementation of community-based tourism in this area has the potential to increase and diversify economic income in this rural community.
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