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Feminicidio as an alarming problem of Mexican society: Process tracing of two selected cases
Kunická, Tereza ; Plechanovová, Běla (advisor) ; Krausz Hladká, Malvína (referee)
Gender violence in Mexico is a problem that affects its society on a long- term basis. Its most extreme form known as feminicide, that is a gender- based murder of women, appears with so much frequency that it can be considered a structural problem yet. Mexico is one of the countries with most cases in Latin America, however, insufficient and ineffective measures taken by the state facilitate their perpetration which is often immune from prosecution. This thesis aims to approximate the issue to the reader and explain the concept of feminicide in given context within its complexity. For that purpose, a process tracing analysis of two selected cases is done; starting from their perpetration to their sentencing by judicial instances. The sentences of both cases became very important milestones. The factors that contributed to the outcome are tracked and afterwards a comparison of tracked causal mechanisms is done. As it was already mentioned, the cases were not selected randomly. Not only are they important for their sentences, but moreover they took place in two Mexican states with traditionally high numbers of committed feminicides, that is in Chihuahua and Mexico State. The results of the analysis suggest that even though Mexico has signed the most important international conventions about women's...
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Augusto Pinochet's Quest for Power; Chilean Coup 1973
Kunická, Tereza ; Raška, Francis (advisor) ; Pečenka, Marek (referee)
This thesis examines Chilean events and development which led to the military coup and consequent establishment of authoritarian regime directed by Augusto Pinochet in September 1973. The regime used strong repressive policy and there were wide human rights abuse in the country; on the other hand, Pinochet was instrumental in economic stabilization of the state which is the base of contemporary economic situation: Chile is one of the most developed countries in Latin America. Taking into consideration the main aim of this thesis, which is defining the most essential factors leading to successful course of the coup and takeover by Pinochet, significant part of the thesis concentrates on development in Chile at the beginning of the 70's, domestic policy of Allende's regime and general political situation in the country, which is necessary to be aware of for understanding following course of events. Another part offers an overview of events that immediately influenced insurgent atmosphere in the army, an analysis of the coup, which led to the fall of Allende's regime and takeover by Pinochet, can be found in this part as well. Last but not least there are specified the factors which were significant for the positive course of the coup; a relevant part dedicates to the American influence over the...
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Genetic factors of resistance to chemotherapy and clinical characteristics of breast tumors.
Kunická, Tereza ; Souček, Pavel (advisor) ; Kleibl, Zdeněk (referee)
Breast cancer is the most frequent malignancy in women population both in the Czech Republic and worldwide. Treatment of this disease involves surgical removal of the tumor, radiotherapy, chemotherapy and hormonal therapy. Recently, targeted biological treatment is also approached. Each patient reacts to the treatment individually and thus high variability in response is common. Multidrug resistance (MDR) presents one of the most important obstacles to successful chemotherapy. MDR is often associated with a decreased intracellular accumulation of anticancer drugs and an increased expression of ABC transporters such asABCC1 of our interest. The ABC family of membrane transport proteins includes the well-known mediators of resistance to anticancer drugs. In particular, ABCB1, ABCC1 and ABCG2 actively perform efflux of various types of drugs from cancer cells, thereby conferring resistance to those agents. The main aim of this study was to asses the genetic variability of the ABCC1 gene in 191 patients with breast cancer and to determinate the expression profile of ABCC1 in 30 patients from this cohort who were treated preoperatively. We evaluated relations between ABCC1 genotype, or phenotype and prognostic factors including the result of chemotherapy. Gene expression was measured in preamplificated...
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