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Evaluation of the Financial Situation of a Company and Proposals for its Improvement
Klimková, Kateřina ; Holešinský, Pavel (referee) ; Bartoš, Vojtěch (advisor)
The intention of the thesis is to evaluate the financial situation of ZEMAS, a.s. in the years 2010 - 2014 using various financial indicators and develop suggestions to improve the financial situation of the company. The work is divided into four parts, the introductory section contains the goals of this work, the used methods and the processing procedure. The second part is then intended to clarify the different concepts of financial analysis. The following third and fourth part is practical, first data from the financial statements are analyzed, and based on this data measures are suggested in the final part.
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Determination of the stoichiometry of the copper complexes with dehydrosilybine A
Klimková, Kateřina ; Mladěnka, Přemysl (advisor) ; Hrdina, Radomír (referee)
Charles University Faculty of Pharmacy in Hradec Králové Department of Pharmacology and Toxicology Candidate: Kateřina Klimková Supervisor: Assoc. Prof. Přemysl Mladěnka, Pharm. D., Ph.D. Consultant: Assoc. Prof. Kateřina Valentová, Ph.D. Title of Thesis: Determination of the stoichiometry of the copper complexes with dehydrosilybin A Silymarin, the standardized extract of the milk thistle (Silybum marianum), is a widely used approved over-the-counter drug that is recommended for a number of liver diseases. Silymarin contains as one of its components 2,3-dehydrosilybinA, which has an appropriate metal binding site in its structure. In general, flavonolignans, due to their structure, can interact with transition metals in the gastrointestinal tract by forming complexes. This property can be useful for the protection against excessive amounts of metals in the body. The aim of this in vitro study was to analyse the interaction of 2,3-dehydrosilybin A with copper, which plays a crucial role in the organism as a cofactor of many enzymes. Although being an essential element, it can, however, be toxic at elevated levels. Stoichiometry, as one of the most important characteristics of the complex, was determined by UV-Vis spectrophotometry in four (patho)physiological pH conditions (4.5; 5.5; 6.8; 7.5)...
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Determination of the stoichiometry of the copper complexes with dehydrosilybine A
Klimková, Kateřina ; Mladěnka, Přemysl (advisor) ; Hrdina, Radomír (referee)
Charles University Faculty of Pharmacy in Hradec Králové Department of Pharmacology and Toxicology Candidate: Kateřina Klimková Supervisor: Assoc. Prof. Přemysl Mladěnka, Pharm. D., Ph.D. Consultant: Assoc. Prof. Kateřina Valentová, Ph.D. Title of Thesis: Determination of the stoichiometry of the copper complexes with dehydrosilybin A Silymarin, the standardized extract of the milk thistle (Silybum marianum), is a widely used approved over-the-counter drug that is recommended for a number of liver diseases. Silymarin contains as one of its components 2,3-dehydrosilybinA, which has an appropriate metal binding site in its structure. In general, flavonolignans, due to their structure, can interact with transition metals in the gastrointestinal tract by forming complexes. This property can be useful for the protection against excessive amounts of metals in the body. The aim of this in vitro study was to analyse the interaction of 2,3-dehydrosilybin A with copper, which plays a crucial role in the organism as a cofactor of many enzymes. Although being an essential element, it can, however, be toxic at elevated levels. Stoichiometry, as one of the most important characteristics of the complex, was determined by UV-Vis spectrophotometry in four (patho)physiological pH conditions (4.5; 5.5; 6.8; 7.5)...
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Determination of the stoichiometry of the copper complexes with dehydrosilybine A
Klimková, Kateřina ; Mladěnka, Přemysl (advisor) ; Hrdina, Radomír (referee)
Charles University Faculty of Pharmacy in Hradec Králové Department of Pharmacology and Toxicology Candidate: Kateřina Klimková Supervisor: Assoc. Prof. Přemysl Mladěnka, Pharm. D., Ph.D. Consultant: Assoc. Prof. Kateřina Valentová, Ph.D. Title of Thesis: Determination of the stoichiometry of the copper complexes with dehydrosilybin A Silymarin, the standardized extract of the milk thistle (Silybum marianum), is a widely used approved over-the-counter drug that is recommended for a number of liver diseases. Silymarin contains as one of its components 2,3-dehydrosilybinA, which has an appropriate metal binding site in its structure. In general, flavonolignans, due to their structure, can interact with transition metals in the gastrointestinal tract by forming complexes. This property can be useful for the protection against excessive amounts of metals in the body. The aim of this in vitro study was to analyse the interaction of 2,3-dehydrosilybin A with copper, which plays a crucial role in the organism as a cofactor of many enzymes. Although being an essential element, it can, however, be toxic at elevated levels. Stoichiometry, as one of the most important characteristics of the complex, was determined by UV-Vis spectrophotometry in four (patho)physiological pH conditions (4.5; 5.5; 6.8; 7.5)...
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Determination of the stoichiometry of the copper complexes with dehydrosilybine A
Klimková, Kateřina ; Mladěnka, Přemysl (advisor) ; Hrdina, Radomír (referee)
Charles University Faculty of Pharmacy in Hradec Králové Department of Pharmacology and Toxicology Candidate: Kateřina Klimková Supervisor: Assoc. Prof. Přemysl Mladěnka, Pharm. D., Ph.D. Consultant: Assoc. Prof. Kateřina Valentová, Ph.D. Title of Thesis: Determination of the stoichiometry of the copper complexes with dehydrosilybin A Silymarin, the standardized extract of the milk thistle (Silybum marianum), is a widely used approved over-the-counter drug that is recommended for a number of liver diseases. Silymarin contains as one of its components 2,3-dehydrosilybinA, which has an appropriate metal binding site in its structure. In general, flavonolignans, due to their structure, can interact with transition metals in the gastrointestinal tract by forming complexes. This property can be useful for the protection against excessive amounts of metals in the body. The aim of this in vitro study was to analyse the interaction of 2,3-dehydrosilybin A with copper, which plays a crucial role in the organism as a cofactor of many enzymes. Although being an essential element, it can, however, be toxic at elevated levels. Stoichiometry, as one of the most important characteristics of the complex, was determined by UV-Vis spectrophotometry in four (patho)physiological pH conditions (4.5; 5.5; 6.8; 7.5)...
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Narative tendences in contemporary art
Klímková, Kateřina ; Fulková, Marie (referee) ; Polcar, Miloslav (advisor)
(in English) KLÍMKOVÁ, K.: Narrative tendencies in the contemporary fine art (artists influenced or inspired by comics in the context of Czech fine art) /Graduation theses/ Prague 2007 - Charles University, College of Education, department of art education, 127 pages Summary description: . , , The theme of this work are narrative tendencies in the contemporary Czech fine art inspiredI by comics or also denotations, which are released from comics schemes. The first part occupy by philosophical situation of story contextual with visual culture. The second part includes the present state of Czech comics (interview with j. Křenek), short history of comics (since 1989) and semiotics of comics. The thirst part is dwelling on interviews with contemporary Czech artists (J. Šalamoun, P. Poš, B. Ovcackova, K. Jene). The Pedagogical section is concerning with area of comics and animation film. These art themes were realized at grammar school Zatlanka and their process is described there (in Pedag. part). At the end of g r a d u o theses is describing concept of author's self art works (3x diaries), made by author s book form. All work is appending very lots of pictures and some of the sections are drawn. Key words: narrative, story, comics, semiotics, diary, author's book, art, art education
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Evaluation of the Financial Situation of a Company and Proposals for its Improvement
Klimková, Kateřina ; Holešinský, Pavel (referee) ; Bartoš, Vojtěch (advisor)
The intention of the thesis is to evaluate the financial situation of ZEMAS, a.s. in the years 2010 - 2014 using various financial indicators and develop suggestions to improve the financial situation of the company. The work is divided into four parts, the introductory section contains the goals of this work, the used methods and the processing procedure. The second part is then intended to clarify the different concepts of financial analysis. The following third and fourth part is practical, first data from the financial statements are analyzed, and based on this data measures are suggested in the final part.
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Accounting and tax consequences of financing a car by leasing and consumer credit
Klimková, Kateřina ; Šindelář, Michal (advisor) ; Molín, Jan (referee)
This work focuses on accounting and tax consequences of financing a car. These forms of financing are leasing and consumer credit. The issue is recorded at a theoretical level, the work describes characteristics and kinds of forms of financing and points to accounting and tax aspects. Theoretical knowledge is applied to an example of specific payment schedules of financial leasing and consumer credit from a leasing company. The example illustrates accounting and tax impacts and compares both types of financing. As a result, the consumer credit is intended for more favourable form of financing in this particular example, but this statement cannot be applied in all cases, because the course of financing can be affected by several variables aspects.
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