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Methods of investigation of murders (selected issues)
Křečková, Veronika ; Musil, Jan (advisor) ; Konrád, Zdeněk (referee)
The main theme of this diploma thesis is the methodology of investigations of murder, respectively the procedure police uses in case of investigation murder. Only selected range of topics is discussed due to limited scope of the thesis. First chapter contains a several legal aspects of fatal offences. Murder, manslaughter and murder of newborn child are chosen as the main fatal offences. Small part of the chapter is devoted to euthanasia and statistics about committed crimes of murder in the Czech Republic. Second chapter describes criminological characteristics, which consists of personality of a criminal, personality of a victim and motives and ways of committing a murder. Third chapter is devoted to typical clues at the place of the crime, including the analysis of DNA, which is discussed in a greater detail, because it is one of the most important type of clues. Forth chapter characterizes typical types of investigation and takes a closer look at problematic of unaccounted-for victims. Fifth and sixth chapter briefly summarize important information about subject and initiation of criminal procedure. Seventh chapter is primarily devoted to investigative and operative acts, divided to crime scene and corpse investigation. In the last eighth chapter the involvement of public is discussed, mainly...
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Euthanasia and the Criminal Law
Křečková, Veronika ; Hořák, Jaromír (advisor) ; Vanduchová, Marie (referee)
The goal of this thesis is to point out the weaknesses of the current terminology of euthanasia and get a closer look on the role of the euthanasia in the Czech legal system with the main focus on criminal law. The secondary goal is to evaluate de lege ferenda legislation. To address this issue comparison of Czech and foreign legislation was included. The analysis leads to conclusion that the term euthanasia needs to be correctly defined to be usable in academic discussion. The definition needs to include differentiation from other conducts that are called euthanasia by the general public even though they cannot be classified as euthanasia by law. The main conclusion of the thesis is that legislation of euthanasia is not a right way forward in the Czech Republic. Nevertheless the Czech legislation should include criminal act of "killing upon request". Alternative to euthanasia should be improvement of palliative care and application of the institute of living will in practice. All future solutions of this controversial issue have to be based on comprehensive and diverse discussion amongst both the public and the legal experts.
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Role of drug transporters in placental transfer of entecavir
Křečková, Veronika ; Červený, Lukáš (advisor) ; Hofman, Jakub (referee)
Charles University Faculty of Pharmacy in Hradec Králové Department of Pharmacology & Toxicology Student: Veronika Křečková Supervisor: PharmDr. Lukáš Červený, Ph.D. Title of diploma thesis: Role of drug transporters in placental transfer of entecavir Entecavir (ETV), an analogue of guanosine, is a highly efficient anti-hepatitis B antiviral drug. It is the first-line therapy for both adults and children. Its use in pregnancy is limited due to a number of factors, including lack of data on placental pharmacokinetics. The placental transition of drugs is frequently controlled by drug transporters. ATP-binding (ABC) transporters, P-glycoprotein (P-gp), breast cancer resistance protein (BCRP) or multidrug resistance-associated protein 2 (MRP2) localized in the apical membrane of syncytiotrophoblast and pumping their substrates in the feto-maternal direction belong to most significant determinants of placental pharmacokinetics. Moreover placental transport of nucleoside-derived drugs can be affected by the activity of nucleoside transporters (NTs); equilibrative nucleoside transporters (ENTs) mediate facilitated diffussion, while the concentrative nucleoside transporters (CNTs) control active influx of their substrates. The aim of the diploma thesis was to describe the role of P-gp, BCRP, MRP2 and NTs (ENTs and...
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Euthanasia and the Criminal Law
Křečková, Veronika ; Hořák, Jaromír (advisor) ; Vanduchová, Marie (referee)
The goal of this thesis is to point out the weaknesses of the current terminology of euthanasia and get a closer look on the role of the euthanasia in the Czech legal system with the main focus on criminal law. The secondary goal is to evaluate de lege ferenda legislation. To address this issue comparison of Czech and foreign legislation was included. The analysis leads to conclusion that the term euthanasia needs to be correctly defined to be usable in academic discussion. The definition needs to include differentiation from other conducts that are called euthanasia by the general public even though they cannot be classified as euthanasia by law. The main conclusion of the thesis is that legislation of euthanasia is not a right way forward in the Czech Republic. Nevertheless the Czech legislation should include criminal act of "killing upon request". Alternative to euthanasia should be improvement of palliative care and application of the institute of living will in practice. All future solutions of this controversial issue have to be based on comprehensive and diverse discussion amongst both the public and the legal experts.
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Methods of investigation of murders (selected issues)
Křečková, Veronika ; Musil, Jan (advisor) ; Konrád, Zdeněk (referee)
The main theme of this diploma thesis is the methodology of investigations of murder, respectively the procedure police uses in case of investigation murder. Only selected range of topics is discussed due to limited scope of the thesis. First chapter contains a several legal aspects of fatal offences. Murder, manslaughter and murder of newborn child are chosen as the main fatal offences. Small part of the chapter is devoted to euthanasia and statistics about committed crimes of murder in the Czech Republic. Second chapter describes criminological characteristics, which consists of personality of a criminal, personality of a victim and motives and ways of committing a murder. Third chapter is devoted to typical clues at the place of the crime, including the analysis of DNA, which is discussed in a greater detail, because it is one of the most important type of clues. Forth chapter characterizes typical types of investigation and takes a closer look at problematic of unaccounted-for victims. Fifth and sixth chapter briefly summarize important information about subject and initiation of criminal procedure. Seventh chapter is primarily devoted to investigative and operative acts, divided to crime scene and corpse investigation. In the last eighth chapter the involvement of public is discussed, mainly...
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