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The effekct of one training of postural stability in patiens with spinocerebellar ataxia
Filipovičová, Jana ; Pospíšilová, Mariana (advisor) ; Jevič, Filip (referee)
We followed the immediate effect of sensorimotor training on postural stability in patients with spinocerebellar ataxia (SCA). We have tried to explain the possible mechanisms of adaptation to change COP, motor learning and neuroplasticity in the field of neurodegenerative changes in the cerebellum. Research Methods: A total of 10 patients with spinocerebellar ataxia (6 men, 4 women) aged 34-71 years, with an average disease duration of 11.6 years participated in the measurement of postural stability. First, we measured the patients with SCA before and after a 15-minute sensorimotor-training exercise, then this group underwent another day of the same measurement without sensorimotor training. As a second control group of 10 healthy subjects served a similar age, who also underwent sensorimotor training. Then we compared the results of posturographic measurement. Results: In the group of SCA patients, sensorimotor training was found significantly lower values in the monitored parameters LENGTH (t stat = 3,537731 > t krit = 2,262157), VELOCITY (t stat = 3,537731 > t krit = 2,262157) and energy to sustain COP (t stat = 2,715085 > t krit = 2,262157), measured on a foam pad with eyes closed. Measurement without making sensorimotor training produced no significant improvement in the results of monitored...
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Quantitative walk tests in children- Research
Frajtová, Aneta ; Jevič, Filip (advisor) ; Slabý, Kryštof (referee)
There is a constant increase of use of the walk tests in children population as part of objective testing. There is absence of complex summary of reference values for healthy children therefore we are not able to test our pediatric patients as fast, easy and objective as we would like to. Due to this fact we decided to create a summary of final results of three chosen walk tests. We have been dealing only with walk tests focused on quantitative aspect of walking in healthy children. We have chosen a walk test focusing on endurance (Six-Minute Walk Test), skilfulness (Timed Up and Go Test) and velocity of walk (10 Meter Walk Test). Methods: We were looking for studies containing only physiology values of healthy children in medical databases such as PubMed, EBSCOhost, UKAZ.cuni.cz, Web of Science and the Google Scholar database. Only studies containing full text and meeting our criteria were chosen. Outcome of this work is a complex summary of all available values of three walk tests, their general description and comparison of all found studies focused on this topic. We made comparison of several chosen parameters (number of tested children, their age, gender, methodology of testing, results and their details). Conclusion: A large number of studies published only average results of all included...
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Rehabilitation in patients indicated to bone marrow transplant
Knotková, Edita ; Jevič, Filip (advisor) ; Medunová, Kateřina (referee)
The bone marrow transplantation is proceeded by tranfusion of blood stem cells to the patient who is indicated to this procedure. Most often indications are hematooncological malignancies. The bone marrow transplantation is for some of the patients the only chance of cure. The conditioning including chemotherapy and radiotherapy of various intensity is necessary for succesful bone marow transplant. It causes several side effects such as immobilization, muscle strength loss and endurance loss. It is possible to prevent or at least slow down these side effects by early rehabilitation. This literature review summarizes present knowledge about influence of physical activity on patient indicated to bone marrow transplant during treatment and in the after-treatment period. Endurance training improves aerobic capacity of the patients and correlates with their quality of life. The resistance training helps to prevent muscle strength loss during immobilization and chemotherapy. Intensity of training sessions is still a subject of discussion because of the instable clinical state of the patient during treatment. There was no negative effect of physical activity proven on patients undergoing bone marrow transplant. Powered by TCPDF (www.tcpdf.org)
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Diagnosis and treatment of back injuries in children with a focus on compressive fractures of vertebral bodies
Kulhánková, Eliška ; Hudák, Radovan (advisor) ; Jevič, Filip (referee)
Bibliographic record KULHÁNKOVÁ, Eliška. Diagnosis and treatment of back injuries in children with a focus on compressive fractures of vertebral bodies. Prague, 2021, 51 pages, 11 atachments. Bachelor thesis. Charles University, 2nd Faculty of Medicine, Department of Rehabilitation and Sports Medicine. Supervisor Radovan Hudák. Abstract Even though compressive vertebral fractures are one of the more frequent injuries among children and adolescents, there is no clear diagnostic procedure established that would lead to a correct diagnosis and suitable therapy. This bachelor thesis summarizes the available information about anatomy and kinesiology of the spine, classification and origin of these fractures and their actual adequate therapy. The practical part describes dependence of clinical examination and imaging methods on the final diagnosis of patients. Furthermore, this thesis looks into the patient's receding pain in time. For the purpose of the study, 30 pediatric patients with spinal compression fracture diagnosis, suspected compression fracture and back contusion were selected. Their collected data from clinical examination and imaging methods (skiagraphy and magnetic resonance imaging) were evaluated using statistical tests. The evaluation indicates that there is no statistically significant...
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Rehabilitation care system for children with leukaemia in Czech Republic and selected countries of Europe
Dostálová, Markéta ; Jevič, Filip (advisor) ; Ptáková, Karolína (referee)
Leukemia is the most common cancer in childhood, making up 30-35% of all oncological diseases in children in the Czech Republic. The most frequent form of leukemia in pediatric patients is acute lymphoblastic leukemia (ALL). This form accounts for 80% of leukemia in children. Other types include acute myeloblastic leukemia (AML), myelodysplastic syndrome (MDS), and chronic myeloid leukemia (CML). Treatment is based on the type and subtype of leukemia diagnosed and usually lasts 1-2 years, provided there is no relapse. Primary treatment involves many side effects, including on the musculoskeletal system, such as chemotherapy-induced polyneuropathy (CIPN) or muscle myopathy as an adverse effect of glucocorticoid therapy. Part of the comprehensive treatment is supportive treatment, which includes rehabilitation (RHB). The aim of this work is to find out and compare whether and under what conditions RHB in pediatric haemato-colongic patients is in the Czech Republic and selected countries of Europe, who and according to what patients RHB and whether clinics have any programs related to RHB in these patients. The general part introduces the issue of pediatric patients with leukemia including the possibilities and adverse effects of treatment. The special part is devoted to research based on...
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Long-term functional-motor consequences of bone marrow transplant in children
Knotková, Edita ; Jevič, Filip (advisor) ; Sedláček, Petr (referee)
The aim of the thesis was to find out and evaluate the long-term functional-motor consequences of stem cell transplantation in children patients and to propose possibilities of testing and physical therapy of these functional-motor consequences. The first part of the thesis is aiming to research available sources about bone marrow transplant and its consequencies. It summarizes possibilities of testing the bone marrow transplant patient`s motor abilities. Furthermore, it summarizes possibilities of physiotherapy in bone marrow transplant patients. The second part of the thesis processes BOT2 results in bone marrow transplant children patients . The thesis evaluates its results compared to healthy population and tests an impact of various factors on function-motor abilities of the patient. The children after bone marrow transplant have mostly below average results in motor tests, especially in manual coordination section. The hypothesis were partially confirmed. Children which underwent radiotherapy have function-motor consequencies in manual coordination and fine motor skills. Children which underwent corticotherapy have function-motor consequencies in manual coordination.
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Electromyographic and clinical evaluation of vincristine-induced peripheral neuropathy in pediatric patients after treatment of acute lymphoblastic leukemia and correlation with the Bruinkins-Oseretsky Test of Motor Proficiency Second edition
Bořilová, Karolína ; Jevič, Filip (advisor) ; Pánek, David (referee)
Title: Electromyographic and clinical evaluation of vincristine-induced peripheral neuropathy in pediatric patients after treatment of acute lymphoblastic leukemia and correlation with the Bruinkins-Oseretsky Test of Motor Proficiency Second Edition Objectives: The aim of this work was to characterize the neurological consequences of vincristine-induced peripheral neuropathy (VIPN) clinically and electromyographically and to evaluate motor skills of pediatric patients after the end of treatment of acute lymphoblastic leukemia. We also determined the relationship between the results of the clinical and electromyographic evaluation of VIPN and the correlation with the results of motor skills tests. Methods: The study involved 35 probands (19 girls and 16 boys) with a mean age of 10.7 years (SD ± 4.3) and a mean time since the last dose of vincristine of 2.3 years (SD ± 1.2). VIPN was assessed using a clinical pediatric-modified Total Neuropathy Score (ped-mTNS) and nerve conduction studies (NCS). Motor skills were assessed using the Bruinkins-Oseretsky Test of Motor Proficiency, Second Edition (BOT-2). Results: The clinical presence of VIPN, according to ped-mTNS, was found in 20 % of probands. Abnormalities in nerve conduction studies were reported by 60.9 % of probands. Of these, 92.9 % had motor...
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