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Comparison of selected disciplines of educational area Man and Nature of the Czech curriculum with the integrated subject Natural Sciences in European curricula
Blaško, Michal ; Stratilová Urválková, Eva (advisor) ; Janoušková, Svatava (referee)
Education policy is one of the important goals of any country, as it affects the lives and employment of its people. Compulsory education in the Czech Republic is defined by the Framework Educational Programme for Basic Education (FEP BE), with science education set out in educational area called Man and Nature. Although this is divided into individual educational fields, its framework concept allows the content of the fields to be integrated according to school programme. However, science has been taught separately in most basic schools for several decades, and any integration efforts are burdened by a lack of examples of good practice. The aim of this paper is therefore to perform comparative analysis of the educational area Man and Nature of the Czech FEP BE and integrated science curricula of selected European countries at the level of lower secondary education (ISCED 2). The analysis identifies topics that are included in foreign curricula but not in Czech curriculum and can thus be an inspiration (in the sense of policy learning), what integrative topics to include in the science education at basic schools. The theoretical part of the thesis describes the integration of natural sciences, both from a historical and curriculum development perspective. Theoretical models describing different...
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Replication strategies of newly discovered giant viruses of amoebas
Blaško, Michal ; Forstová, Jitka (advisor) ; Sýkora, Michal (referee)
Giant viruses are a group of viruses with genome composed of double-stranded DNA molecule. They are characterized by the creation of giant viral particles, the size of which varies between 150-1500 nm. Also, their genomes are huge reaching sizes of up to 2,5 Mbp. The viruses replicate either in the cytoplasm or they exploit for their replication both nucleus and cytoplasm. Therefore, they are called, nucleocytoplasmic large DNA viruses (NCLDVs). During their replication cycle, the giant viruses induce the creation of viral factories, which provide morphogenesis of new virions. The aim of this thesis is to summarise current knowledge of selected representatives of the giant viruses, and to describe their replication strategies. Furthemore, this work aims to discuss discoveries made in relation to this particular group if viruses. Thanks to the discovery of giant viruses, another group of small viruses was identified - the so-called virophages (viruses of viruses). Virophages have the ability to take advantage of the giant virus infecting an amoeba to realize their own replication strategy. In some members of the Mimiviridae family there was described a presence of an genome element providing a unique way of immunoprotection of giant viruses from being infected by the Zamilon virophage. Key words:...
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