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Process improvement of logistic in the production
SUCHÁNKOVÁ, Hedvika
My diploma work is focussed on the organisation of materials flow in a selected enterprise. In the frame of the studied enterprise I devoted special attention to the flow of packaging and manufacturing materials demonstrated on the operations of a particular manufacturing hall. Based on the implemented analysis the enterprise management decided to optimise the unsatisfying state of processes in compliance with the principles of lean production. The described re-structuring was aimed at a decrease in the stock of finished products packed in boxes and in an increased efficiency of responds to potential client requirements, further at specification of rules and setting responsibilities in the fields of logistics and manufacturing. The concluding section of the diploma work is focussed on potential improvement measures which could be taken within the studied enterprise.
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Možnosti kompostování biologicky rozložitelných komunálních odpadů v Adamově
Jordánková, Kateřina
This diploma thesis comes out of legislative requirements for a decrease in the quantity of biologically decomposable communal waste put in disposal sites and the support of composting. The thesis is focused primarily on making a draft of gathering and collecting biologically decomposable waste, its processing by composting and a draft project on a composting plant in the conditions of Adamov city. The plan of the whole system was set on the basis of the specification of the source of biologically decomposable communal waste and its weight flow depending on the type of a built-up area, evaluation of contemporary used technologies of composting with regard to the quantity of processed waste.
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Does monopson exist on the player's market in the NBA?
Pilmaier, Jan ; Hudík, Marek (advisor) ; Koubek, Ivo (referee)
This paper deals with the question whether the structure of the labor market in NBA is monopson or not. On the data from the NBA season 2011/12 I estimate player's marginal productivity using two stages least square model. In the first step I determine winner-loss ratio based on players' performance statistics. In the second step I use the results from the first model to predict team's revenues. This effect is controlled by other economic and social variables. Based on this model's results I determined that even though this market is not perfectly competitive, the results are not strong enough for monopson. Short player market could be described as winner-take-all market while on the market for centers there is a balance between pivots and owners and players can obtain their salary equal to their productivity. Then I discovered the superstar effect, according to which stars get bonuses to their salary against the rest of players. Finally it was found out that rookie contracts decrease players' rewards. On the market for centers the life cycle hypothesis holds.
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Determinants of housing demand in Moravian-Silesian Region
Rusanová, Yvonne ; Mičúch, Marek (advisor) ; Chytil, Zdeněk (referee)
The bachelor thesis aims to define determinants of housing demand. I implemented the regression analysis on a quarterly data from Moravian-Silesian region. Regression analysis has demonstrated significant impact of mortgage rate, net disposable income of households and unemployment rate in on housing demand. 1% increase in mortgage rate would decrease the number of house and dwelling transfers by 9,1%. Coefficients of other significant variables are not testifying because of the presence of correlation. Surprisingly, prices of houses and dwellings have appeared as irrelevant.
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Metabolism of uric acid during mammalian evolution
Mančíková, Andrea ; Krylov, Vladimír (advisor) ; Stibůrková, Blanka (referee)
Uric acid is the end product of purine metabolism of humans and some higher primates. In other mammals enzyme urate oxidase is capable to further convert uric acid to allantoin. During evolution of primates several mutations in urate oxidase gene had occured, led the enzyme to decrease its activity or to complete loss of function. What was the initial impetus for the utilization of uric acid and what biochemical traits of uric acid led to a tendency to retain a major of this metabolite production in the bloodstream? Uric acid has antioxidant capabilities and it is scavanger of free radicals. Increased levels of uric acid in blood has an effect on acute and chronic elevations of blood pressure. It is possible that hyperuricemia helped to maintain blood pressure under low-salt dietary conditions of primates during the Miocene. This mechanism probably have allowed to stabilize bipedalism our ancestors. Uric acid has an important role as a neuroprotector. As inhibitor the permeability blood-brain barrier, uric acid limits the infiltration of undesirable substances to the neurons and prevents central nervous system against the formation of inflammatory diseases. Such as neurodegenerative diseases may be caused by reduced serum uric acid levels. Uric acid protects against peroxinitrite damage tissues in the...
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The analysis of elections to the Chamber of deputies of the Czech republic between 1996 and 2002 by aggregate data method
Reimer, Petr ; Lebeda, Tomáš (advisor) ; Novák, Miroslav (referee)
2002 were accompanied by a gradual decrease of voter turnout, decrease in the number of parties that exceed the five-percent threshold and by a decrease in regional variability of party support. In that period we could also distinguish a substantial regional dissimilarity of support between left-wing and right-wing parties. According to the following analysis we could explain those differences by various socioeconomic parameters of electoral districts. The most specific electorate among all parliamentary parties could be indentified with the Christian Democrats, whose support is regionally based and positively correlated with the regional rate of religiosity. The analysis of aggregate data allows us to explain the relation between party support and regional characteristics of electoral districts but does not permit explanation of the motives of individual voting behavior. Those conclusions could be made on the basis of public opinion research. This analysis is in general in accordance with the findings of research agencies, concerning the role of economic parameters as the main explanation factors of party support. Nevertheless, the relevance of this statement still remains to be grounded on a longer series of election data. Powered by TCPDF (www.tcpdf.org)
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Healthy life style education focused on colon and rectum cancer prevention
BARTONĚK, Jaroslav
This work is engaged in colon and rectum cancer which is much more obvious problem in the Czech Republic than in the rest of European countries. This work is focused on its prevention and a diagnostic of this serious disease. The healthy lifestyle habits and an advance anamnesis can reduce death risk to a great extent. There is a project called ``The colon and rectum cancer prevention {--} a drop of blood saves a life{\crqq} as a part of this work which is destined for upper {--} primary pupils. The purpose of this work is consistent with the first objective of the National Oncology Program of the Czech Republic. This program is focused on professional education support of tumor prevention in Czech schools, an increased public awareness of tumor prevention, a decrease of smoking by youth and women, and also an abatement of the fluctuations of nutrition and lifestyle. This goal has been fulfilled. There is a question of whether the results of this program reflect the true situation. If this type of education project is undertaken by primary schools in the Czech Republic we will have to wait some years to see the results.
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Study of structural differences among 14-3-3 protein isoforms.
Macáková, Eva ; Gryčová, Lenka (referee) ; Obšil, Tomáš (advisor)
The 14-3-3 proteins are a family of important regulatory proteins, found in all eukaryotes, which are involved in many cellular processes. In this diploma thesis, we studied structure/function relationships of 14-3-3 proteins, in this case it was the influence of the structure of H8-H9 loop on the binding affinity in barley isoform hv 14-3-3A and human isoform 14-3-3ζ. According to former results, hv 14-3-3A binds to a ligand with lowest affinity, which could be caused by present of a glycin in H8-H9 loop, while in other isoforms there is a serin on the same position. We measured the binding affinity in protein hv 14-3-3A WT and its mutant, which contained the serin instead of the glycin in H8-H9 loop. For comparison, we also measured the binding affinity of human isoform 14-3-3ζ containing the serin in H8-H9 loop and its mutant, where the the serin was replaced by the glycin. Proteins were expressed in E. coli cells strain BL21(DE3) and then purified. The dissociation constant for the binding of peptide pRaf-259 labeled with fluorophores FITC and ATTO was measured using both the fluorescence correlated spectroscopy and the steady-state fluorescence intensity. Our results showed that in both isoforms the mutation of H8-H9 loop causes decrease in the binding affinity.
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Regulation of tobacco consumption
Sabová, Kristýna ; Písař, Pavel (advisor) ; Loužek, Marek (referee)
The theme of this bachelor work is if regulation of tobacco are efficient and lead to decrease of cigarette consumption and another tobacco products. The work is focused on regulation with excise taxes which are one of the most important regulation tool. In theoretic part of the work are written the most common presented reasons and incentives for tobacco regulation and what is the impact on the population. The main part of the work is based on the theoretical part and tries to explain how is the consuption changing in time regarding the higher consumtion taxes. If those regulations have influence on demand for tobacco products and the demand declines.. This bachelor describes changes of official demand and does not treat the demand for tobacco products on black market. The goal of this work is to show if public and supranational institutions can decrease the tobacco products consumption with different regulation tools.
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Network attached storage
Pavlíček, Ladislav ; Vokoun, Tomáš (advisor) ; Pavlík, Jan (referee)
The thesis explores the subject of data storage options, focusing on Network Attached Storage (NAS) solution and its potential target users. The theoretical part of the thesis reviews the overall data storage solutions used in the past, compared to the current ones. The further description of NAS is provided, highlighting its specifications and possibilities for use. In addition, the analysis of different methods of data storing on a hard disc drive is conducted and resulting data reliability is examined and assessed. The aim of this bachelor thesis is to recommend NAS for suitable user groups based on their needs and habits. To gather relevant data and identify those characteristics, the research method of survey based data collection is being used. As a result, the particular potential user group for NAS, currently unaware of its benefits and uses, is identified. This group is characterized by its online content use and consumption patterns in areas of video and music content consumption, photo sharing, file backing-up habits, cloud usage, etc. Furthermore, the thesis expands on the potential benefits for those users and provides practical suggestions for use in regard to their identified needs. In the last part of the thesis, collected survey data are being compared to the related national survey data provided by the Czech Statistical Office. The concluding analysis reveals a trend of decreasing interest between year 2015 and 2016 for using cloud data storage solutions in general, mainly in terms of storing and sharing of photos, movies and music. Finally, the limitations of survey data collection are being discussed, focusing on particular internal and external factors which could have influenced the survey results.
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