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Programs for design of systems in particle optics
Lencová, Bohumila ; Zlámal, J. ; Jánský, P.
The paper describes a number of programs used by us in the design of systems for surface studies and deposition that simulate the focusing, transport and deflection of charged particles. In deposition and implantation systems often quite intense beams of ions are used where the space charge effects become prohibitive. Therefore we have extended our 2D FEM program EOD, equipped with a Windows graphical interface, with an option to compute space charge limited beams.
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Parallel single-cell analysis of active caspase-3/7 in apoptotic and non-apoptotic cells
Ledvina, Vojtěch ; Klepárník, Karel
Caspases are proteases that play key role in the process of apoptosis, the programmed\ncell death. Among them, caspase-3 and -7 are main executioner caspases that cleave\nmany vital proteins during apoptosis and after their widespread activation, the process\ncannot be reversed. To analyze caspase-3/7 activation within single cells, a miniaturized\ndevice for parallel analysis of eight samples was developed. The assay is based on the\nmodified luciferin-firefly luciferase bioluminescence (BL) system. Individual\nsuspended cells were collected and transferred into detection microvials using a\nmicromanipulator. The bioluminescence was detected using a photon counting head\nwith cooled photcathode. The LOD suitable for detection of active caspase-3/7 in both\napoptotic and non-apoptotic cells was reached.
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Antidecubital Care as a Nursing Problem
KŘÍŽOVÁ, Monika
This thesis deals with the issue of providing antidecubital care and observes the fulfilment of nursing interventions in the care about non-self sufficient patients. During performing her duties, every nurse encounters the issue of decubitus ulcers formation and with this related antidecubital care. Thus, it can be stated that the occurrence of decubitous ulcers serves also as the indicator of the quality of provided nursing care. A lot of people think that the problem develops particularly in elders, but young people who are bedridden after injuries and accidents are also affected and this complication degrades the quality of their life. The thesis is divided into theoretical and empirical parts. The theoretical part describes the anatomy of skin and its function, decubitus and classification of decubitus ulcers are defined, their localization with characteristics of predilection sites are specified, outlining complications in decubitus ulcers. The theoretical part pursues antidecubital care with the division into subheads on positioning, antidecubital aids, nursing interventions, and the mission of the European Pressure Ulcer Advisory Panel is described. The separate chapter includes the risk assessment of decubitus ulcers formations, as is e.g. Norton scale, etc. The last chapter embraces the specification of conservative and surgical treatment of pressure sores. The aim of the research examination was to determine whether the nurses perceived antidecubital care as a nursing problem and to map the opinions of the nurses relating to antidecubital care. Three research questions were set to achieve the objectives: first, what the pitfalls of nursing care were on the part of the nurses, secondly, what areas within antidecubital care were neglected and finally, how antidecubital care at selected inpatient wards was provided. The research was implemented at the chosen inpatient wards in České Budějovice Hospital, PLC, from the period of February to April 2014. The research file consisted of the general nurses and the medical assistants. A hidden participant observation was conducted and then questionnaires with 15 questions that were closed or semi-closed were distributed to the nurses. 45 questionnaires were handed out, 31 handed back and all 31 questionnaires could be processed. Thus, the total return of the questionnaires was 69%. Questions in the questionnaire were based on the observation criteria. The hidden participant observation was processed and plotted on the observation sheet and then classified according to the given criteria. After delivery, the returned questionnaires were checked and evaluated graphically. All results were processed using Misrocoft Office Excel program, were plotted in graphs with keys and descriptions. By processing and comparing the results, we ascertained that in some fields the opinion of the nurses was different from the practice that was really performed. It could be also caused by the fact that antidecubital care is very time-consuming, demanding and comprises a lot of nursing interventions. Sufficient number of aids with which the ward is equipped is relevant as well, be it preventive aids or medical ones. And last but not least the organization of the care. At present, the time spent on completing documentation is increasing and the time that can be used by nurses for contacting a patient and satisfy his/her needs is decreasing. Nevertheless, the patient´s state and his/her contentment reflect and demonstrate our care. After previous arrangement, the results of our research examination will be communicated to the ward sisters at the selected inpatient wards where the research examination was performed.
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Non-invasive methods for sex and steroid homones determination in gibbons of the genus Nomascus
Bolechová, Petra ; Bartoš, Luděk (advisor) ; Pavel, Pavel (referee)
The gibbon primates of the family Nomascus are classified as critically endangered species, and, to date, basic understanding and information about their biology is missing. With regard to the status of these animals in the wild and captive populations in zoos, being familiar with their reproduction, may improve captive breeding programs. Data collection in this study was to be carried out by the practical use of non-invasive methods (polymerase chain reaction for DNA extraction and enzyme immunoassays), using faecal samples for analysis. The first method, polymerase chain reaction, was used for sex determination in juveniles, because of their coat colour and visual similarity of secondary sex characteristic in both sexes; it is not possible to determinate sex without handling the animal. Another main purpose of this study is to try and answer the hypothesis regarding the ovarian cycle of females, factors influencing their hormone concentration and also the onset of sexual maturity in females and the timing of their fur colour change. Hypotheses were checked by monitoring the concentration of progesterone and oestrogen faecal metabolites and by evaluation of the composition of breeding groups of gibbons with the ZOO influence. During a four year period (from 2010 till 2014), there were a total of 51 animals analysed from 16 different zoos with a faecal sample count totalling 1618 samples. The results confirmed the use of noninvasive methods for sex determination, and thus ensuring the maximum welfare standards. Endocrinological analysis confirmed the hypothesis of the influence of the environment (ZOO) to the hormone concentrations and female´s pregnancy effect in conjunction with her age on the final results of the male - father hormone concentrations. The initial information in this study is the confirmation of the onset of ovarian cycle in young females without connection to their fur colour change and a significant factor of a mother´s impact and her territoriality. This study is the first to present a long term monitoring of ovarian cycles in females and hormone concentrations of other individuals, both male and female, and from various age groups. The results allow us to understand the possible impact of zoo environments on the reproductive status of these gibbons and contribute to the general improvement of breeding management.
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Energy assessment of building
Žůrek, Petr ; Horák, Petr (referee) ; Hirš, Jiří (advisor)
Diplomová práce se zabývá energetickým sektorem v Ruské Federaci se zaměřením na sektor budov a jejich energetickou efektivnost. Je zde vytvořen základní přehled předpi-sů a norem týkajících se sektoru budov a dotační programy vytvořené Ruskou vládou na snížení energetické náročnosti. V praktické části je provedeno energetické hodnocení dané budovy v podmínkách Čr a Ruské Federace. Výpočty energetických bilancí budovy jsou prováděny pro klimatické podmínky daných zemí a v souladu s národními předpisy. Na základě energetických bilancí jsou navrženy opatření na úsporu energie. V závěru je provedeno ekonomické posouzení, s ohledem na rozdílné ceny energií a nákladů na provedení návrhových opat-ření v České republice a Ruské Federaci.
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Analysis and Testing of Concurrent Programs
Letko, Zdeněk ; Lourenco, Joao (referee) ; Sekanina, Lukáš (referee) ; Vojnar, Tomáš (advisor)
V disertační práci je nejprve uvedena taxonomie chyb v souběžném zpracování dat a přehled technik pro jejich dynamickou detekci. Následně jsou navrženy nové metriky pro měření synchronizace a souběžného chování programů společně s metodologií jejich odvozování. Tyto techniky se zejména uplatní v testování využívajícím techniky prohledávání prostoru a v saturačním testování. Práce dále představuje novou heuristiku vkládání šumu, jejímž cílem je maximalizace proložení instrukcí pozorovaných během testování. Tato heuristika je porovnána s již existujícími heuristikami na několika testech. Výsledky ukazují, že nová heuristika překonává ty existující v určitých případech. Nakonec práce představuje inovativní aplikaci stochastických optimalizačních algoritmů v procesu testování vícevláknových aplikací. Principem metody je hledání vhodných kombinací parametrů testů a metod vkládání šumu. Tato metoda byla prototypově implementována a otestována na množině testovacích příkladů. Výsledky ukazují, že metoda má potenciál vyznamně vylepšit testování vícevláknových programů.
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Marketing audit of the festival Divadelná Nitra
Surovková, Simona ; JEŽEK, Vlastimil (advisor) ; SYROVÝ, Daniel (referee)
Divadelná Nitra is an international theatre festival with over 20 years of tradition, which annually brings a selection of the best European productions of the season to Nitra. Visitors are offered a presentation of the top contemporary theatre productions, exceeding to dance, physical, visual and music theatre, new and inspirational art forms, rich accompanying and work programme, and many other art and cultural activities. The festival is an internationally recognized event and is of vital importance in the context of the current Slovak theatre. Yet, as many other non-profit organizations, it has been struggling each year to maintain a stable financial situation, and despite an enormous effort and an experienced management team, the festival cannot avoid some organizational problems. Several of them are related to marketing of the organization. The aim of this marketing audit is to analyze the current situation of the festival Divadelná Nitra, to evaluate the state of its own marketing activities, and, along with discovered results, to propose solutions that could help to improve marketing of the festival Divadelná Nitra.
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Work in social integration process of adults with intellectual disability.
SVITÁKOVÁ, Iveta
In my bachelor thesis, I dealt with the use of work activities in the process of social integration of adults with mental disabilities, the aim was to create, implement and evaluate regular work activities intended to a specific group of adults with mental disability and focused primarily on the development of social integration. The thesis is structured into six chapters. The first of them is focused on the definition of mental disability, characteristic of adulthood as an important developmental period in human life, and on adulthood of individuals with mental disabilities with a goal to find and identify the specifics that were needed to be taken into account when working with this target group of people. The following section is devoted to the social integration, its determinants and the environment in which it operates. I continued with the outputs in the third chapter, where I focused on key competencies, which them are the necessary basis for social integration, especially social and personal skills and communication skills, necessary basis. Targeted professional development can be realized through educational activities, but has to respect the specificities of the participants and voluntary participation. Both of these assumptions can be fulfilled within the leisure education using adequate pedagogical methods. For this reason, I decided to focus my attention on these areas at the end of the chapter. The fourth chapter is devoted to work and work activities, namely the definition of concepts, their characteristics and importance and role of work activities in human life, or a person with mental disability. Based on all acquired theoretical knowledge and using previous experience with the target group in the fifth chapter, I designed a specific training program based on the work and activities focused on the development of selected key competences. The educational program volunteered four participants, but I have decided to follow the development of competencies of three participants because one participant attended the program very irregularly. The program has been implemented three times a week, two and a half hours for seven months (from October 2015 to May 2016) in the premises of the training centre Mo-zai-ka. At the beginning of the realisation of the created educational program, the participants agreed that we will adhere and develop good habits necessary for good relations within the group and the results of the work. On a basis of the individual characteristics of the participants, I prepared the work, which should also contribute to the development of social and personal and interpersonal skills. I have continuously monitored and recorded them. During the implementation of the program, I put emphasis on repetition, patient negotiations with participants and creating a friendly atmosphere. After completing the training program, I evaluated the development of competencies in three selected participants. On that basis, I concluded that the biggest change was in the communicative competence. I also experienced a change in social and personal competencies, however, results varied widely among individual participants. Yet, I believe that the goal of the thesis was achieved. These results show that education in leisure time, based on work activities may lead to the development of social and personal and interpersonal skills that are for adults with mental disabilities necessary in the process of social integration. This thesis can be an interesting source of inspiration for the realisation of similar programs aimed at social integration of persons with mental disabilities.
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Diets for food allergies
DOBRUSKÁ, Klára
I have chosen topic Diet with Food Allergy as a topic of my bachelor thesis. This illness is quite common these days. It affect infants mostly but allergy of cow´s milk protein of children under three years disappears itself mostly. There is increasing amount of causes when patient suffers more allergies. Number of people who have the most serious reaction the anaphylactic shock, icreeases. It can end with death. Doctors recommend to patients to strictly follow the elimination diet which is basic treatment of this illness. The most accurate diagnosis of illness (immunological or not) is another important factor for effective treatment. I have chosen three aims for this bachelor thesis. First to find out if patients are informed about their illness. Second to map eating habbits of people with food allergy. Third the evaluation of correctness of daily menus. I used approach of guality research. Research group consisted of six respondents with different food allergy. Those respondents wrote down their weeks menus. Menus were evaluated with program Nutriservis and it was assessed if it follows recommended dietary value. Suitable intake of energy and essential nutrients was calculated for every respondent. It was evaluated if respondents follows priciples of rational diet and if their diet contains sufficient amount of minerals and vitamins. Questionnaires were another key point of this research. Questionnaires were about illness know-how of patients and who has instructed them about it. It was found out the patients hasn´t got enough information about their illness and half of them has no idea which essential nutrients, minerals and vitamins could lack in their diet. It resulted from menus simultaneously that five of six respondents do not follow principles of rational diet and eat very monotonously. Only one respondent follows strictly elimination diet others violate diet exceptionally. Respondets would appreciate other research would focus on creation of special centres and training of doctors and nutritional therapist who would be focused on food allergies. Spreading the information about illness not only to patients but to public also is really important. Another important point is to increase amount of books about food allergies at the market.
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The use of new technologies in teaching mathematics
BUMBÁLEK, Roman
Modern information technologies accompany all of us in our daily life. They not only use to serve to our work and for the entertainment, they even have got a great potential to be used in the education. The submitted thesis deals with the appropriate utilization of the special IT application in the pedagogic process, especially in teaching of maths, the topic of trigonometric functions. The aim of this thesis is to create structures with a high potential of the modern technology handling. To tackle this task the graphical program GeoGebra was chosen due to its qualities for creating dynamic structures and the other advantages presented further in the thesis. To the created constructions the detailed instructions how they can be constructed are added. The thesis is also accompanied by worksheets with solved tasks, focusing on the application of trigonometric functions in real situations.
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