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Level on public knowledge concerning of helth insurence policy
ŘEHÁKOVÁ, Jana
Public health insurance is an important part of the Czech health system. In the Czech Republic the model of national health insurance is administered using system of several insurance companies. The main target of these companies is to collect insurance rate from the payers and to cover health care provided to the insuree. The aim of this work is to map and assess professional and non - professional public knowledge of the system of the public health insurance. Three goals were set within the work. The first one was to find out the level of the professional public knowledge of the public health insurance. The second one was to find out the level of the non - professional public knowledge of the public health insurance. The third one was to compare both groups knowledge of the public health insurance. To realize the above mentioned aims three hypotheses were set. Hypothesis No.1: Most of the professional public is informed about the valid legal arrangement of the public health insurance. Hypothesis No. 2: Most of the non -professional public is informed about the valid legal arrangement of the public health insurance. Hypothesis No. 3: There is no difference between the professional and non - professional public knowledge of the valid legal arrangement of the public health insurance. To prove the set hypotheses the form of quantitative research was used. The technique of questionnaire was used for data collecting. For practical part the identical questionnaire for both professional and non - professional public was used. The research group of the questionnaire investigation was formed by respondents living and working in České Budějovice. The professional public within the research work was formed by people who work or worked in the health or social sphere. The final research group was formed by 200 respondents of professional and 200 respondents of non - professional public. The target of the thesis and partial aims were accomplished. The first two hypotheses were proved. The third one was not proved by the research work. It has been investigated what areas is professional and non - professional public most or less informed in. The results of the research work may be used for publication in the professional journals.
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Atomistické simulace uspořádávání v niklových slitinách pod vlivem mechanického napětí
Buršík, Jiří
Systems containing up to six alloing elements typical of advanced Ni-based superalloys were modelled.their ordering was simulated at atomic level using a Monte Carlo approach with púeriodic boundary conditions and Kawasaki dynamics.molecular dynamics routines were embedded into standard kinetic Ising model to account for relaxing of local atomic positions.Straining computer experiments show that elastic parameters and bulk modulus undergo comparatively large changes at the beginning of ordering process.
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Preemptive analgesia & the role of drugs affecting nervous system in potentiatio n of analgesics efficacy
Slíva, Jiří ; Kršiak, Miloslav (advisor) ; Geršl, Vladimír (referee) ; Kozák, Jiří (referee)
The aim of our research is was to determine whether new and already clinically successfullyused anticonvulsant levetiracetam has a preemptive or therapeutic effects in the model of postoperative pain in rats. The second objective of our research was to determine whether guaifenesin increases the efficiency even analgesic NSAIDs, with different selectivity for COX-2 (ibuprofen, nimesulide and celecoxib) in the model of visceral pain in mice. As Previously, it was discovered that guaifenesin increases theabsorption of paracetamol, we investigated whether guaifenesin also affect plasma levels of one of the NSAIDs tested, andnimesulide. The third main objective of our research was therefore to determine whether cannabinoid receptor agonist CP-55940 increases the analgesic activity of diclofenac in amodel of visceral pain model in mice and inflammatory pain in rat.
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The effect of analgesics and their combination with neurotropic drugs on pain and brain mediators
Soukupová, Marie ; Kršiak, Miloslav (advisor) ; Farghali, Hassan (referee) ; Rokyta, Richard (referee)
The first aim was to investigate changes in analgesic efficacy of several analgesics in combination with selected drugs affecting nervous system after systemic administration. The second aim was to ascertain changes of levels of pain mediators in vivo in supraspinal brain structures (in periaqueductal gray matter, central amygdala, striatum) in pain and under the drug influence. The analgesic efficacy of combinations of analgesics with neurotropic drugs was investigated in the writhing test in mice. Interactions between analgesics and neurotropic drugs were evaluated by the isobolographic analysis, which enables to distinguish the supra-additive (synergistic) interactions from solely additive and sub-additive ones. A possible negative effect of neurotropic drugs on motor functions was determined in the rota-rod test in mice. Changes of levels of pain mediators in the brain during pain and under the drug influence in rats were measured by microdialysis in vivo coupled with a high performance liquid chromatography. A model of inflammatory pain induced by intraplantar injection of carrageenan and a model of neuropathic pain produced by a spared sciatic nerve injury model were used in rats. We evaluated pain in plantar and von Frey filament test. Our microdialysis experiments revealed that inflammatory pain...
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The course of microsporidiosis caused by Encephalitozoon cuniculi in experimental model
VOTOČKOVÁ, Tereza
Microsporidia are obligate intracellular parasites causing disease called microsporidiosis. The infectious strategy is a spore - a highly organized cell which gives a rise to the infection of the host. This bachelor thesis records the progress of microsporidiosis provoked by the infection of the experimental model of the species of microsporidia Encephalitozoon cuniculi, namely of the genotype ECIII. The theoretical part includes the familiarization with microsporidia. In this part, there are first records leading to paying more attention to them and initiating their closer examination. This section describes both the biological characteristics and the systematic categorization of microsporidia and the description of a spore as the infectious stage of life cycle, which enables get into the host body where microsporidia reproduce and cause diseases. The sources of microsporidia are mentioned as well as the ways of transmission and microsporidia species most commonly detected in human whose attention is devoted mainly to Encephalitozoon cuniculi - its history and development, the infectious progress in hosts, the detection, and the treatment. The practical part describes the methodical process of the way of monitoring of microsporidiosis on experimental models in a form of laboratory mice of inbred immunocompetent BALB/c and the mice with severe combined immunodeficiency SCID. The mice were orally infected with spores of Encephalitozoon cuniculi genotype ECIII, which was isolated from steppe lemming (Lagurus lagurus). The progress of infection was monitored both on the basis of coprological examination of mouse feces and on the basis of the examination of tissue and body fluid samples. The processing of individual samples was carried out with the aid of molecular diagnostics in the parasitological laboratory AV ČR in České Budějovice. The DNA from individual tissues and body fluids was isolated by using a commercially supplied kit, QIAamp DNeasy Blood & Tissue Kit ( QIAGEN), the feces were treated with a commercially supplied QIAamp DNA Stool Mini Kit (QIAGEN). The principle was to destroy the individual spores and to obtain the pure DNA which was suitable for further processing. Subsequently, the two-step polymerase chain reaction was carried out. providing rapid multiplication of DNA. The next step was a gel electrophoresis which arouses the division of the DNA into individual fragments on the basis of different molecular weights due to the effect of unidirectional electrical current. The fragments were visualized by UV transilluminator at a wavelength of 312 nm linked to a computer. The part of the research was the albendazole treatment of BALB/c mice. The drug was orally administered in the range from 28th to 42nd day after the infection. The results on progress of microsporidiosis through various organs and tissues, including the involved treatment, were recorded in well arranged tables. At the end of this bachelor thesis, there is a summary of the research and its comparison with previous studies. The results showed that microsporidia may be a threat not only for people suffering from immune deficiency, but thanks to their successful survival in the organs of immunocompetent hosts and their ability of activation from the undetectable level, they emphasize the danger of latent microsporidiosis as a risk and life-threatening factor for groups of people undergoing chemotherapy or organ transplantation where the patients can receive inflected graft from a donor.
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A judgment of the predicability efficiency of the prediction models on the basis of financial statements of the Altreva Ltd. and Jitex Inc. corporations
Kulda, Jakub ; Strnad, Lucien (advisor) ; Kotáb, Jiří (referee)
The thesis deals with the predicability efficiency of prediction models, which represents integral part of financial analysis. These models could be divided into bankruptcy prediction and solvency models. The aim of the listed models is to determine level of financial health of selected companies with a few year prospects. As a representative of the companies, which went bankrupt, was selected Jitex Inc., which fold in 2009 and going concerns represents Altreva Ltd. In the theoretical part various financial ratios and prediction models are described with their expected characteristics. These descriptions also include explenation of models construction. The practical part provides concrete results of used prediction models and financial ratios of Altreva and Jitex. A special attention is paid to Jitex Inc. in 2006, where the prediction models could be misjudged by high level of artificially overvalued profit. The practical aim of this study is an extensive specification of tests along with their suitability to predict fitness of companies within the Czech economy framework.
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Comparison of the tax burden from dependant and indepedant activities in the selected member states of the European Union
Bierhanzlová, Adéla ; Láchová, Lenka (advisor) ; Matějka, Václav (referee)
This thesis focuses on a tax burden of an income tax payer in the European Union. The main aim of the thesis is to compare the tax burden and differences in determination of tax liabilities in selected member states of the European Union which are the Czech Republic, Slovak Republic, Spain, Sweden and United Kingdom. In the first part of thesis, characteristics of the tax burden are described, as performed by a tax to GDP ratio and implicit tax rates. The second chapter deals with principles of determination of the tax liability and social security insurance within selected states. The tax burden within selected states is analyzed in the last chapter. Tax burden of the employee and entrepreneur was analysed through three model taxpayers (single taxpayer, married taxpayer with two children and married taxpayer with one child and with dependant spouse) with four different wage or income level.
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Measuring corruption in developed countries
Bajzíková, Anna ; Baxa, Jaromír (advisor) ; Janda, Karel (referee)
The complex issue of corruption has attracted much attention over the last 20 years. The problem was analyzed mostly in the context of developing and transition countries, though not only the recent financial crisis showed the severity of corruption also in the world's most developed countries. This thesis analyzes twelve currently available corruption assessments for a cross section of 39 developed countries in the period 2007-2010. The thesis categorizes these assessments into three basic generations and characterizes the weaknesses and limitations of particular methods. The analysis is based on determination of relationship between individual corruption measures and recognizes specific aspects of corruption actually measured by particular indices. With the exception of strictly opinion poll-based corruption indices, the first and the second generation of corruption indices correlate well for a set of developed countries. This indicates that the sector specific indices, e.g. expenditure corruption assessment, are in analyzed countries closely related to the overall political corruption levels. An applied hierarchical cluster analysis gives better picture of otherwise inconsistent developed countries corruption rankings and divides countries into ten homogeneous groups. However, the analysis...
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Removal of residual stress in thin sheets by tension leveling
Dymáček, Martin ; Návrat, Tomáš (referee) ; Petruška, Jindřich (advisor)
Tension leveling is a process used in the steel industry in order to eliminate any shape imperfections of cold-rolled thin strips. The master thesis deals with developing a computer program that generates basic parameters of tension leveling line. The theoretical part of the thesis summarizes the types of the shape imperfections in strips, their causes and the principles of their elimination. This part also presents the mechanism of tension leveling and describes the present-day design of tension levelers. The practical part of the thesis starts with an analytical description of stress-strain behaviour of strip during tension leveling (supposing the simplified conditions). A computer program that allows devising basic parameters of tension leveling line is created on the basis of these analytical relations. The program results are successfully verified by numerical model based on the finite element method (FEM) created in the program ANSYS. Then the interdependencies of certain input and output parameters of created program are determined. These interdependencies can be used as effective design of tension leveling lines.
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