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Selected somatic signs and motor performance of boys aged 13 and 15 years old
ŠVEJDOVÁ, Petra
The aim of this thesis was to describe the evolution of body size, level of motor and physical skills of children aged 13 and 15 years. The research was carried out in primary schools in the South Bohemian Region. The results were processed for each age group separately, they were compared with the reference files and are presented in tables and graphs. To compare the files, there was used Student´s T-test and Z-score. The boys also filled in a questionnaire in which they answered how often in sports and what sports they pursue. A similar questionnaire was presented to their parents. Questionnaires were also focused on diet and nutrition.

Occurance of the chosen risk in term of the gender about children.
MÁCHALOVÁ, Lenka
Abstract The problems of hazardous behavior with adolescents are getting into the foreground of the wide public. The problem of hazardous behavior with children, adolescents or young people is very real, not only in the Czech Republic, but all over the world, at prezent, it is a worldwide problem representing a substantial social problem with which many specialists in the field of psychologists, psychiatrics, educators, politics and other participating institucions, World Health Organization, are dealing. The Publisher results of research are pointing to a non- decreasing occurrence of hazardous behavior, where it comes to a basic shifting to a lower age group from the point of view of the gender eguality, when the girls and boys engage in hazardous behavior with different circumstances, conditions and occurrence. A whole range of research on this theme exists, but it does not fully concern the hazardous behavior, for instance in connection with information technologies, cell phones and using of habit-forming drugs. The thesis is divided in the theoretical and the practical part. In the theoretical part, the selected forms of hazardous behavior with children and the gender problems are described. In the practical part, the quantitative research method has been chosen,a method of gathering data by means of a questionnaire. The research summary for questionnaire inquiry was created by pupils attending the 7 th to 9 th school year of the primary schools in the South Bohemian region. The aim and purpose of the thesis was to find the appearance of selected risk behaviour with the children from the point of view of the gender, and to map the differences with a view to the gender problems. The aim was accomplished. There were four hypothesis stated. H1: The boys are a more endangered group in occurance of a hazardous behavior in connection with alkohol than the girls. H2: There is a higher risk in connection with usaje non-legal drugs about boys than about girls. H3: Boys are more endangered in the occurrence of a hazardous behavior in connection with habit-forming behavior relating to virtual milieu. H4: Girls are more endangered in connection with communication technology. The thesis may be used as an information survey of a selected hazardous behavior with the children and with the gender problems. The results of the research can be used as informative material for the lay public, for children and adolescents, for parents and other specialists (anti-drug coordinator, methodic of school prevention and not least for the education or as basics for a further following research aktivity. Further, the results of the research can be used for a closer determination of suitable prevention programs. For this reason, the results of the research were given to schools, where the research observation proceeded for the purpose of enhancement of the primarily preventive activity.

The Neolithic settlement area Hrdlovka: analysis of ceramic material
VONDROVSKÝ, Václav
The presented diploma thesis aims primarily to the analysis of ceramic material obtained from the Neolithic settlement area Hrdlovka excavated during salvage terrain excavation since the year 1987 to 1990. For the purposes of processing of finds and excavation situations the complex database and digitalised site plan were created in the GIS interface. The analysis of ceramics was targeted particularly to the establishing of settlement area relative chronology and separating of individual settlement phases. Current description system of Czech Neolithic pottery was modified and replenished with regard to Hrdlovka´s finding situation specifics. The process of chronological analysis comprising also spatial data was divided into several steps. Resulting sequence comprises 10 settlement horizons (Hrdlovka A - J), which correspond to nearly uninterrupted development since the early stage of the Linear Pottery culture to the late stage of the Stroked Pottery culture. Important pieces of knowledge were obtained mainly about the transitional phase between the both cultures, which was in Hrdlovka documented by two settlement horizons. The analysis of ceramics spatial distribution and some architecture characteristics are also presented in limited range.

Progress of the system of public health insurance and health insurance companies in the Czech Republic for the period 2000 - 2015
Pecková, Tereza ; Lukášová, Tereza (advisor) ; Bartůsková, Lucia (referee)
This bachelor´s thesis analyzes the basic funds of health insurance companies for the period 2000 - 2015 in the Czech Republic, especially the creation of resources and their use and the entire system of public health insurance in the Czech Republic. Basic funds are one of the components of the overall economy of health insurance companies. First it is necessary to describe the market of the insured. The insured create and use the finances within public health insurance. Also important are contributions from the state budget for those insured by the state. We can conclude that the cost of health insurance companies are rising and that population is aging in the Czech Republic. However, this is not a balanced linear growth. The number of pensioners grew at a slower rate of growth, but according to population development forecast, there should be faster growth in the number of pensioners in the following years. Significant growth in cost is particularly noticeable in the age category of 80 and above, and increasingly more people should live up to this blessed age, also thanks to modern public health.

Development of prostate cancer radiotherapy from the 80s to the present day
SUCHANOVÁ, Markéta
Prostate cancer (CaP) remains the most common cancer diagnosed in men. This desease has worldwide increasing incidence. In the Czech Republic incidence has tripled during the last 20 years. The increase of the mortality is much more slower, but CaP is still the third leading cause of cancer-related death in men. CaP treatment management options may include active surveillance, radical prostatectomy, brachytherapy and external beam radiation therapy. The radiotherapy occupies an irreplaceable position. It is used as a curative therapy for clinically localized CaP with a low and intermediate risk. In the case of high risk CaP and locally advanced tumors are often treated with the addition of the hormonal therapy, which enhances tumor control and overall patient's survival. The radiotherapy is also used in some cases as an adjuvant treatment following a radical prostatectomy, as well as a salvage therapy in a biochemical relapse or as a palliative treatment if the cancer progresses. The aim of this study is to provide an overview of the development of CaP radiotherapy from the 80s till the present day. The specific objective of the study is to assess the incidence of the radiation-related complications (RRC) in patients with CaP treated with IMRT and PT. Among the methods of processing this thesis was using secondary data analysis. Practical information were obtained during the visits to the Department of the Radiation Oncology at the Hospital Ceske Budejovice a.s. (NCB) and the Proton Therapy Center Czech s.r.o. (PTC). During these visits was observed the radiotherapeutic treatment of the patients with CaP and valuable information were obtained through interviews with Mrs.Vančurová, MD and Mr. Vítek, MD., Ph.D., MBA This study analysed the incidence of the acute and late RRC in patients with CaP treated in these facilities. The acute and late side effects was assessed for GU and GI toxicity using RTOG / EORTC score. The specific problems were measured with the CTCAE v.4.0 scale. The overall incidence of the RRC was subjected to the statistical hypothesis testing using a two-sample unpaired t-test. The examined sample consisted of the 30 patients with CaP irradiated at NCB and the 30 patients from PTC with low, intermediate and high risk CaP. It was found that for the patients from NCB the rectum mean dose was 40,7 Gy and the mean dose of bladder was 39,4 Gy. For the patients treated at PTC the mean dose to the rectum was 13,2 Gy and to the bladder 11.1 Gy. This is related to the incidence of the RRC. Acute GU and GI toxicities Grade 2+ occurred in 33 % and 23,3 % of the patients treated in NCB. With a median follow-up of 22 months there was late GU toxicity Grade 2+ in 13,3 %. Late GI toxicity Grade 2+ occurred in 26,7 %, which exceeds incidence of the RRC described in the literature. Incidence of late GI toxicity Grade 3 and 4 was also increased, it appeared in 10 % (3 patients). Furthermore in one case cancer reoccurred and metastasized one and half year after the radiotherapy. In PTC no acute or late Grade 3+ toxicities were observed. Acute GU and GI toxicities Grade 2 occurred in 13,3 % and 6,7 %. After median follow-up of 21,5 months there was incidence of late GI toxicity Grade 2 3,3 %, late GU toxicity appeared only Grade 1 in 13,3 %. There was found statistically significant difference in occurrence of RRC in patients treated in NCB and PTC. The hypothesis that PT reduces the incidence of the radiation side-effects compared to the IMRT technique in the patients with the prostate cancer was confirmed. The prostate can move greatly during the day. It is recommended using CBCT, which is part of new linear accelerators at NCB, to check the position of the prostate before each irradiation. This study provides an overview of the treatment of CaP and may serve to increase of awareness of the RRC. The main contribution can be seen in the comparison of a standard approach with a promising alternative.

Biology knowledge of the 9. year- class pupils at town basic schools
NOVÁKOVÁ, Eliška
This thesis deals with the testing of knowledge testing of the natural history of pupils in 9th classes of primary schools through didactic test. The knowledge of natural history was tested with 118 pupils (67 boys a 51 girls) in districts ofPříbram a Mirovice. The best knowledge of pupils was found in the field of zoology, and the lowest knowledge in the field of inanimate nature. The results were compared with the results of the survey in primary schools in Brno, in district of Příbram, in Kolín and in South Bohemia region (2012). At village schools pupils demonstrated the highest knowledge in the field of zoology, compared to other regions, where pupils demonstrated the best knowledge of human biology.

Financial literacy of elementary school pupils
Čudová, Lucie ; Burian, Stanislav (advisor) ; Stará, Dana (referee)
The bachelor thesis deals with the topic of financial literacy of primary school pupils after the inclusion of the financial education in the Education Plan of primary schools. With the use of professional literature, theoretical part of this bachelor thesis defines the Standards of financial literacy and assesses the benefits and issues of financial education of primary school pupils. The conclusion of the theoretical part of this bachelor thesis is dedicated to the history of financial education between 2005 and 2014. The practical part of the bachelor thesis is dedicated to international survey of PISA (Programme for International Student Assessment) and to author´s own testing. With the use of PISA´s surveys and author´s own testing, the state of pupils´ financial knowledge and skills was analysed during the periods before and after the financial literacy was included in the Framework Education Plan. Fifteen-year-old boys were tested through the PISA project, students of elementary and secondary schools and grammar schools were tested by the author of the thesis. Consequently, the level of knowledge was compared between the secondary school pupils and grammar school students using PISA´s survey and author´s own testing. A survey has been done with the teachers and management of the tested schools as a part of own testing. Own testing and the survey were done with the help pupils and teachers from primary schools in Čáslav and adjacent villages. In the final part of the bachelor thesis, an assessment of findings and results was done in order to improve teaching of financial literacy and a comparison of results of pupils that were tested through PISA and by the author of the bachelor thesis was made.

Epidemiology of tuberculosis - reaction on vaccine BCG
FOŠUM, Pavel
Epidemiology of tuberculosis-reaction to BCG vaccine World Health Organization records nine million people worldwide who fall ill with tuberculosis and more than three million who die of this disease a year. Tuberculosis has been known for a long time and despite the discovery of Mycobacterium tuberculosis etiological role by Robert Koch, the invention of RTG diagnostics by Roentgen and effective treatment using antibiotics by Waksman as the first, this disease still represents a considerable risk for society. Prevention using BCG vaccine has positive as well as negative aspects. This thesis is focused on describing newborn vaccination coverage, occurrence and duration of side and adverse effects after the application of BCG vaccine during the first days of life and on the influence on the following compulsory vaccination. We used the method of quantitative research in the form of epidemiology descriptive study using the technique of individual data collection and analysis. As a research area the group of children born in 2004, 2005, and 2006 was used. The group of 804 children (410 boys and 393 girls) was selected by the technique of random cluster sampling. We found out that out of 804 respondents 98.6 % were vaccinated with BCG vaccine. The group of 11 children was not vaccinated due to: HBsAg positivity of mother, low birth weight or health problems. Reaction after BCG vaccination was not healed until the next planed shot in 307 children (38.1 %). There were 4 people with no reaction at all to BCG (0.8%). The most frequent side (adverse) reaction after vaccination was scar unhealed at the time of next planed vaccination in 274 cases, (34.1%). Monoreactions accounted for more than a half of recorded reactions. Reaction time period was in the range from 11 to 300 days. Median of reaction time period was 30 days. We did not find any serious adverse reaction. Our research demonstrated, that frequency of side and adverse reactions after BCG vaccination is high (38.1 %). These are mainly benign side effects. We found that these reactions lead to postponing of the subsequent vaccination of the compulsory vaccination scheme in all who reacted to BCG vaccination. The occurrence of side reactions after BCG vaccine raises the question of appropriateness to carry out the BCG vaccination in first days of life. The results of this thesis can be used as a pilot study for the whole country study of mapping side and adverse reactions and further consideration of compulsory vaccination scheme.

Hereditary and non-hereditary factors affecting the quality of rapeseed oil
Zemanová, Kateřina ; Sedláková, Vladimíra (advisor) ; Bečka, David (referee)
This literature review study quality of rapeseed oil in details, depending on heritable and non-heritable factors. Consumption of rapeseed oil is growing every year and in addition to use in human nutrition is also used in animal feed industry or as fuel for motor vehicles. The rapeseed oil has especially a large representation of oleic acid. Furthermore, it is linoleic acid and linolenic acid and undesirable erucic acid, whose quantity is considerably reduced. It is important to mention glucosinolate content, as antinutritional substances, which is reduced together with erucid acid which is known as "00" rapeseed oil. All these components are described in details in this review. The content of fatty acids in rapeseed oil may be influenced both genetic factors and environmental factors. Selection plays a significant role in breeding. Suitably selecting the correct genotypes along with environmental influences can reach the desired target. An important role is played by the synthesis of fatty acids, where in using a desaturation enzymes of fad series, there is desaturation of stearic acid to oleic acid, linoleic acid and linolenic acid. With QTL method, it can be detected genetic background of quantitative traits. Major genes responsible for the quality of rapeseed oil are located on the chromosome A, namely A1, A3, A5 and A8, which are mentioned in the work.

Special access of the radiology assistant to interventional procedures in diagnostics of oncological patients
CANDROVÁ, Daniela
In my work I deal with the peculiarities in approach of a radiology assistant to interventions in diagnostics of oncological patients. Biopsy has a special importance in diagnostics of neoplasm. It is essential for histological and cytological diagnostics. The aim of this work was to find out the incidence of bioptic interventions on oncological patients during one year at radiology department at České Budějovice hospital plc, and to compare the advantages and disadvantages of used modalities. The work proceeds from the presumption that the number of interventions carried out under the sight control without the use of ionizing radiation methods is growing. In the theoretical part of my work appear descriptions of bioptic methods of intervention radiology regarding oncology and its methods, biopsies, screening methods used at biopsy (ultrasound controlled biopsy, computer tomography controlled biopsy, magnetic resonance controlled biopsy, skiascopic controlled biopsy), instrumentarium, especially the needles used for tissue extraction (puncture and bioptic needles), characteristics of oncological patients, the principle of tumour disease, carcinogenesis, oncologically changed tissue, and basic diagnostics of oncology disease. The practical part reveals the number of biopsies performed in 2012 at České Budějovice hospital plc, under computer tomography, ultrasound and mammography machine control, and the number of other interventions on oncological patients, namely localization of impalpable breast lesion, percutaneous drainage of the urinary tract under skiascopic control. Standard methods regarding these interventions and biopsies are described focusing on the advantages and disadvantages of their use for different organs in the body. I also described radiology assistant?s work and created photo documentation of given interventions. In 2012, 96 biopsies were performed under any of the mentioned diagnostic screening methods at radiology department of České Budějovice hospital. They represent 0,06% of the total of 171 466 diagnostic interventions at this department in the respective year. At the same time they represent 3,4% of the total of 2844 interventions of the ČB radiodiagnostic department of that period. From the whole number of 96 biopsies, 79% were performed on oncological patients. No biopsies were performed under magnetic resonance or skiascopic- skiagraphic control. Since the formation of a tumour is supposed to be the main somatic risk which an individual after a low intensity radiation faces, I supposed that the number of bioptic samples taken under sight control without the use of non ionizing radiation is rising, which significantly contributes to radiation protection. It is not univocally assigned which screening method is the best for biopsy. Usually we chose the biopsy that can screen best the site in different organs and that allows the safest, the fastest and the economically most convenient procedure. The chosen method should allow the doctor chose the site for sample extraction. The choice also depends on the habits and the technical equipment of given hospital. In view of the fact that according to this work computer tomography is the most commonly used method for bioptic extractions, and under magnetic resonance control no biopsies are performed, the prestige and importance of a radiology assistant grows up, because their presence at modalities using ionizing radiation is commonly indispensable. The hypothesis of my work has not been proved. Concrete results do not support the operative hypothesis of y work. However, I can recommend concessive long-term type and multicentrically elaborated sample studies. I would be grateful if this work provided an information base for radiology assistants´ training and for interventions in the diagnostics of oncologically ill people.