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Carboxymethyl Cellulose As The Binder For
The Lithium-Sulfur Batteries
Jaššo, Kamil
Demand for the high energy density batteries significantly increased along with the rapid development of new power source depending technologies. While these technologies are rapidly evolving, the battery industry is lagging behind unable to meet the demand. As a prospective successor to the existing li-ion battery technology, can be the high-capacity lithium-sulfur battery system (Li-S). The most commonly used composition of the positive electrode material of Li-S batteries is a mixture of sulfur, carbon and PVDF1 binder mixed in NMP2 solvent, which is (according to the WHO3) slightly toxic. The article deals with a replacing PVDF with organic non-toxic water-soluble binder.
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Hydrosolubilization of BODIPY for optical labelling of biomolecules
Bartoň, Jan ; Kotek, Jan (advisor) ; Vrábel, Milan (referee)
1 Abstract This work aims at showing synthesis and potential use of water-soluble fluorescent probes based on BODIPY. The preparation of probes containing bioorthogonal mono- and heterobifunctional functional groups was demonstrated. Ground work was done at the optimisation of reliable, scalable and fast sulfonation of BODIPY in 2,6-positions. A protocol for handling sulfonated BODIPY has been established; especially for the exchange of counterions. In counterion se- lection, their relation to synthetic pathway and biocompatibility were taken into consideration. The second part of the work shows series of water-soluble fluorescent probes, into which can be easily introduced bioactive or bioorthogonal functional groups. This can be used for click chemistry in connection with turn off/on probes or fluorescent sensing of molecules or ions. All this can be done in aqueous solution without organic solvents, which is relevant for biochemical, analytical and imaging applications. Keywords BODIPY, bifunctional, water-soluble, fluorescent probe, solubilization, biocompa- tible probes, bioorthogonal reaction, BODIPY sulfonation
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Bifunctional BODIPY for optical labelling of biomolecules
Bartoň, Jan ; Kotek, Jan (advisor) ; Henke, Petr (referee)
The water-soluble derivate of BODIPY was prepared, which will be further modified in order to prepare bioorthogonal bifunctional BODIPY. Target application of this derivate is fluorescent probe for labelling of biomolecules. Main goals of this thesis were optimalization of synthesis of BODIPY core and sulfonation to positions 2,6. It was found out that sodium salt of sulfonated BODIPY shows good solublility in water and methanol, but it is poorly soluble in less polar solvents. Based on these findings DIPEA salt of sulfonated BODIPY was prepared, which shows outstanding range of solubility from water to dichlormethane. These findings will be used for synthesis of bifunctional water- soluble BODIPY. Further, the potential of Pd-BODIPY complex for detection of CO was reasserted which will be further investigated. Keywords BODIPY, bifunctional, water-soluble, fluorescent probe, fluorescence, protein labelling, solubilization
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