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National Repository of Grey Literature 2 records found  Search took 0.00 seconds. 
The effect of sleep on consolidation of episodic-like memory in rats
 Petránová, Erika ; Kelemen, Eduard (advisor) ; Svoboda, Jan (referee)
We can notice the positive effects of sleep on many functions of our organism. For a long time we have observed the interconnection between sleep and memory and today we already know, that different sleep phases correlate with an improvement of different memory types. One of the hypotheses, that explain the positive effect of sleep on strengthening of the memory representations, is its irreplaceable active role in the process of memory consolidation. The memory consolidation of episodic type in animals, which processes memories into events with time and space context, could according to this theory occur due to two phase sleep process, in which each phase has a specific role. The theoretical part of this thesis will familiarize the reader with the problematic of organization of time and space in our brain, and introduce him to the foundations of electroencephalography (EEG) and offer a detailed introduction into the discussed hypothesis of active sleep consolidation. The practical part is then focused on the confirmation of the already mentioned hypothesis through the combination of comparison of results from the behavioral task of 2 groups of animals with different sleep manipulation and of the analysis of EEG signal recorded during the experiment before and after the training. The behavioral task...
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Neurobiological Correlates of Episodic-like Memory
 Oravcová, Ivana ; Nekovářová, Tereza (advisor) ; Stuchlík, Aleš (referee)
Declarative memory is characterized as a conscious, explicit memory. Declarative memory consists of two essential systems, semantic memory and episodic memory. Episodic memory enables us to recall specific past events. A simplified model, so called Episodic-like memory is often used to study episodic memory mechanisms. According to this model, all events are stored in a contextual framework consisting of three basic components: identity of the object ('what' happened), temporal information ('when' it occurred) and spatial information ('where' did it happen). This type of memory is testable not only in humans but also in animal models. Aim of this diploma thesis is to study the neuronal substrate of individual components of episodic memory in healthy volunteers by means of functional magnetic resonance imaging (fMRI) and ecologically valid tasks designed in virtual reality environment. Results obtained in the fMRI paradigm show that apart from common neuronal substrate of episodic memory, additional brain structures are responsible for recollection of individual components of the episodic-like memory. Behavioral data indicate that the demands of the recollection of individual components is not equivalent. Additional analyses with parcellation of the brain to individual structures and consecutive...
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