Vliv spánku na konsolidaci paměti epizodického typu u potkanů

Petránová, Erika

We can notice the positive effects of sleep on many functions of our organism. For a long time we have observed the interconnection between sleep and memory and today we already know, that different sleep phases correlate with an improvement of different memory types. One of the hypotheses, that explain the positive effect of sleep on strengthening of the memory representations, is its irreplaceable active role in the process of memory consolidation. The memory consolidation of episodic type in animals, which processes memories into events with time and space context, could according to this theory occur due to two phase sleep process, in which each phase has a specific role. The theoretical part of this thesis will familiarize the reader with the problematic of organization of time and space in our brain, and introduce him to the foundations of electroencephalography (EEG) and offer a detailed introduction into the discussed hypothesis of active sleep consolidation. The practical part is then focused on the confirmation of the already mentioned hypothesis through the combination of comparison of results from the behavioral task of 2 groups of animals with different sleep manipulation and of the analysis of EEG signal recorded during the experiment before and after the training. The behavioral task...

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