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Modification of a multi-recess hydrostatic bearing pad geometry
Šimara, Vít ; Robenek, Dětřich (referee) ; Svoboda, Petr (advisor)
In the design of a hydrostatic bearing, basic analytical expressions assuming parallelism of sliding surfaces and simple geometry can be employed. In this study, the properties of a specific pocket shape were investigated even under conditions of tilt, which can arise from assembly errors or asymmetric loading. Based on experimental data, a Computational Fluid Dynamics (CFD) model of hydrostatic lubrication has been developed and validated. A constant flow through all recesses was considered and conditions of no movement of the sliding surface were assumed. The model was subsequently modified to a variant with discharge grooves separating individual recesses and a variant with variable recess position relative to the centre of the pocket. The results demonstrated that the pocket's ability to carry asymmetric loading increases mainly with increasing distance of the recess from the centre, followed by their size. However, this ability comes at the cost of higher performance losses in hydrostatic lubrication. The results of this work can be used for the design of pockets with different methods of pocket support or alignment.
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Application of Modern Technologies to Concept of Production of Jigsaw Puzzle
Novotný, Michal ; Slaný, Martin (referee) ; Sedlák, Josef (advisor)
This bachelor´s thesis deals with the suggestion of the convenient technical and material variation which would be suited for the production of a puzzle. It describes attributes, purposes and use of puzzles. 3D model was created in a parametric design application called Autodesk Inventor. Then the work describes the making of the puzzle. The puzzle mould was milled into SikaBlock® M 450. The puzzle pieces were printed by 3D printer REPRAP using FDM method. In addition it deals with the alternative production of the puzzle. The technical and economic evaluation of the technical and material variations is available in the conclusion of this work.
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Attributes Calculation for Prediction of Mutation Effect on Protein Function
Šinkora, Jan ; Filák, Jakub (referee) ; Jaša, Petr (advisor)
This thesis deals with issues of bioinformatics, machine learning, algorithms and data structures. The thesis is based on existing applications, Caver and Deleterious, developed by students from the Faculty of Informatics, Masaryk University and the Faculty of Information Technology, Brno University of Technology. The Deleterious framework calculates protein attributes that are important for the prediction of the effect of protein mutations on its function. Caver is a tool that finds tunnels in the 3-dimensional model of a protein. The goal of the thesis is to extend these applications by adding more attributes to the prediction process that could lead to improved prediction. The added attributes are related to detection and measurement of protein pockets.
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Analysis of NC programming options for enclosed pockets
Janda, Jiří ; Osička, Karel (referee) ; Polzer, Aleš (advisor)
The aim of this paper is to provide an overview of the available strategies for milling of closed pockets. In particular, it focuses on advanced programming using CAM programs. In the next parts, the work is focused on the analysis of the force load of tools in the machining of the pockets. Here it focuses on the course of forces in milling at the corner of the pocket using different methods of analyzing this load. There are also ways to reduce this burden.
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Analysis of NC programming options for enclosed pockets
Janda, Jiří ; Osička, Karel (referee) ; Polzer, Aleš (advisor)
The aim of this paper is to provide an overview of the available strategies for milling of closed pockets. In particular, it focuses on advanced programming using CAM programs. In the next parts, the work is focused on the analysis of the force load of tools in the machining of the pockets. Here it focuses on the course of forces in milling at the corner of the pocket using different methods of analyzing this load. There are also ways to reduce this burden.
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Application of Modern Technologies to Concept of Production of Jigsaw Puzzle
Novotný, Michal ; Slaný, Martin (referee) ; Sedlák, Josef (advisor)
This bachelor´s thesis deals with the suggestion of the convenient technical and material variation which would be suited for the production of a puzzle. It describes attributes, purposes and use of puzzles. 3D model was created in a parametric design application called Autodesk Inventor. Then the work describes the making of the puzzle. The puzzle mould was milled into SikaBlock® M 450. The puzzle pieces were printed by 3D printer REPRAP using FDM method. In addition it deals with the alternative production of the puzzle. The technical and economic evaluation of the technical and material variations is available in the conclusion of this work.
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Attributes Calculation for Prediction of Mutation Effect on Protein Function
Šinkora, Jan ; Filák, Jakub (referee) ; Jaša, Petr (advisor)
This thesis deals with issues of bioinformatics, machine learning, algorithms and data structures. The thesis is based on existing applications, Caver and Deleterious, developed by students from the Faculty of Informatics, Masaryk University and the Faculty of Information Technology, Brno University of Technology. The Deleterious framework calculates protein attributes that are important for the prediction of the effect of protein mutations on its function. Caver is a tool that finds tunnels in the 3-dimensional model of a protein. The goal of the thesis is to extend these applications by adding more attributes to the prediction process that could lead to improved prediction. The added attributes are related to detection and measurement of protein pockets.
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