National Repository of Grey Literature 4 records found  Search took 0.00 seconds. 
Analysis of arrhythmias in experimental ECG recordings
Olšanská, Eva ; Janoušek, Oto (referee) ; Ronzhina, Marina (advisor)
This diploma thesis deals with analysis of electrograms recorded from isolated rat hearts. In theoretical part, basic principles of electrocardiography and differences between rat and human EG records are described. Types of arrhythmias and methods for classification and quantification of arrhythmias are also described. Examples of pathologies found during the manual classification and results of the analysis of the QTc interval duration are presented. An occurrence of premature beats is then compared between experimental groups. Finally, the method used for the automatic analysis of electrograms including the graphical user interface is described and the results of its evaluation using real data are presented
Analysis of arrhythmias in experimental ECG recordings
Olšanská, Eva ; Janoušek, Oto (referee) ; Ronzhina, Marina (advisor)
This diploma thesis deals with analysis of electrograms recorded from isolated rat hearts. In theoretical part, basic principles of electrocardiography and differences between rat and human EG records are described. Types of arrhythmias and methods for classification and quantification of arrhythmias are also described. Examples of pathologies found during the manual classification and results of the analysis of the QTc interval duration are presented. An occurrence of premature beats is then compared between experimental groups. Finally, the method used for the automatic analysis of electrograms including the graphical user interface is described and the results of its evaluation using real data are presented
Interakce haloperidolu s IKto-kanály u srdečních buněk: matematický model
Pásek, Michal ; Bébarová, M. ; Matejovič, P. ; Nováková, M.
In this work, the effect of antipsychotic drug haloperidol (1 µmol/l) on transient outward potassium current (IKto) in rat ventricular myocytes is explored and mathematical model of haloperidol interaction with IKto-channels introduced.

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