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Německý Brod Gradual by Paul of Mělník from 1506
Blechová, Světlana ; Kubík, Viktor (advisor) ; Zapletalová, Jana (referee)
The presented dissertation thesis called " Německý Brod graduale by Paul Melnik in 1506" is bound to my bachelor thesis, which also dealt with manuscript from the Paul of Melnik's workshop. The introduction of the thesis summarizes the already existing literature on the topic (Chap. 1). Then the following chapters are focused on the illuminator of the studied graduale (Chap. 2.1); they are also engaged in the questionable issues of provenance and dating the graduale, which is allegedly dated in 1506, however, the illumination contained in it rather refers to the graphic analogy (ies) of A. Dürer, which was (were) issued not earlier than in 1511 (Chap. 2.2). The thesis also includes a chapter which is dedicated to the donator of the manuscript (Chap. 3.1). Moreover, there are emphasized problems of literary fraternity and art of Utraquism in Bohemia as well (Chap. 3.3). The chapter 3.2 tries to summarize the works of the illuminator Paul of Melnik, and also to describe his artistic character. The last chapters are devoted to the decoration of the graduale and to possible analogies within the illuminations (Chap. 4).
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Gradual Paul of Melnik from 1530
Blechová, Světlana ; Kubík, Viktor (advisor) ; Ottová, Michaela (referee)
Bachelor thesis called " Louny Gradual by Paul Melnik in 1530" first summarizes the existing literature on the topic, which occurs soon after the half of the 19th century (Chapter 1). The names of the purchaser and illuminator of the Louny Gradual are documented in the first part of the Gradual's explicit (IG 8, f. 427v). The explicit also includes the date and provenance of the Louny Gradual, which was completed in 1530 for Utraquist literary fraternity at St. Nicholas'Church in Louny (Chapter 2.4). The Louny Gradual belongs among the last written Latin Utraquist choral books. It contains one of the largest collections of Kyrie and Sequences. Paintings in both parts Gradual (IG 8a, b) are in the academic literature considered the decline in artistic standards. However, the nearly intact Louny Gradual characterizes the spectacular color components and efforts to adopt new ideas from the west, mainly represented by M. Schongauer's and Dürer's prints.
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The Litoměřice Gradual of 1517
Kabourková, Jana ; Kubík, Viktor (advisor) ; Jarošová, Markéta (referee)
The Litoměřice Gradual of 1517 Subject of this thesis is a detailed analysis of monographic Utraquist Gradual from Litoměřice, dated to the year 1517 (Lovosice, SOA, IV C 1).The study involves a review of the published literature to date on and consistent formal and iconographic analysis decorations. In the introduction, the manuscript was partially studied in terms of cultural and historical context of its origin and dating. The donors, Jakub Ronovský and Vaclav Řepnický, are introduced in the extant sources and in connection with a major Utraquist Brotherhood at the Church of All Saints in Litoměřice. Chapter 2.2 extensively elaborates on the issue of dating the manuscript. Personality anonymous, who painted manuscript, evaluated chapter 2.3. Unknown origin painters compensate in this work a comprehensive study of creative expression illuminators and their possible inspiration. In the foreground are highlighted especially the analogy with the second generation of the Danube School and graphic designs from the late 15th century. The second part of the study elaborates formalized Gradual, the individual illuminated folio orientation puts into context the development of contemporary art on the basis of particularized analogies. Besides the comparison with published choral manuscripts Janicek...
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Fabián Puléř - Prague illuminator
Svitáková, Kristina ; Zlatohlávek, Martin (advisor) ; Zapletalová, Jana (referee)
Thesis "Fabian Puléř - Prague's illuminator", who was active between years 1550 - 1562 in Prague's Old Town, focuses on one of the leading illuminators of the 16th century in Bohemia. First, it pursues his personal and professional life, then clearly focuses on sources and literature concerning the person or Fabian Puléř. Then continues with the interpretation of the most important hymnbooks and 16th gradualscentury with Puléř's illuminatations concerning: Gradual of the Metropolitan Cathedral of St. Vitus, Žlutický Hymn Book, Kaňkovský Hymn Book, Hymn Book of the City Louny. There is also interpreted the 16th century time and in the Czech lands, in particular the environment of bourgeois guilds and literary brotherhoods in terms of ordering, but also in terms of their sociological behavior at that time.
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The Work of Fabián Puléř
Svitáková, Kristina ; Hlaváčková, Jana Hana (advisor) ; Zlatohlávek, Martin (referee)
This thesis deals with Fabian Puléř, an illuminator who lived in the 2nd half of 16th century in Prague, and about his workshop in the Old Town. The main theme is the graduals and their fragments, which were made in his shop or are believed to be made there (the Metropolitan St. Vitus Temple Gradual, the Gradual of Čáslav, the Gradual of Žlutice, three illuminations from the collection of National Gallery in Prague, the two-part St. Valentine's Gradual from the Old Town, the fragments of Kaňkovský Gradual, the Gradual of Louny owned by Jan Táborský of Klokotská Hora, the Gradual of Český Brod), their description and cataloguization. Apart of critically rewieving the literation on the subject to this day, my thesis follows the life of Fabian Puléř regarding archival sources and also influences and impulses behind his work. It also contains crucial chapter about iconography of utraqistic musical manuscripts and about the litterateur brotherhoods, who ordered these hymnic books.
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Dose-response curves
Hezoučký, Martin ; Hlávka, Zdeněk (advisor) ; Maciak, Matúš (referee)
Title: Dose-response curves Author: Martin Hezoučký Department: Department of Probability and Mathematical Statistics Supervisor: doc. RNDr. Zdeněk Hlávka, Ph.D., Department of Probability and Mathematical Statistics Abstract: In this thesis, we deal with the process of research and development of new medical substances with a focus on statistical methods used to determine appropriate doses. For this purpose, we examine the dose-response relationship. First, we describe a typical procedure for the development of a new drug. Second, we focus in detail on the MCP-Mod method. Third, we propose a new method based on the theory of gradual change models. This approach tests whether the administration of the drug has a significant effect. If so, the dose with desired effect is estimated using an appropriate model. Specifically, we provide an esti- mate using linear, quadratic and Emax gradual change models. We also describe a construction of a confidence interval for the point of change and also for the dose with the desired effect. The advantage of the proposed method over the MCP-Mod is the determination of the confidence intervals. Finally, we apply the above mentioned methods to data from the U.S. Tox21 research program and compare the results based on several tested substances and clearly demonstrate the...
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Graduals from the Workshop of Jan Táborský of Klokotská Hora
Součková, Ema ; Royt, Jan (advisor) ; Brodský, Pavel (referee) ; Hlaváčková, Jana Hana (referee)
The dissertation focuses on the decoration of 16th century choral manuscripts. The first part is devoted to the person of Jan Táborský of Klokotská Hora (1499-1572) who was a scribe and an owner of a scribe manufactory, and to the most significant illuminators of the the 16th century who contributed to the decoration of songbooks in the Lands of the Bohemian Crown. Attention is given not only to the illuminators to whom Jan Táborský of Klokotská Hora assigned the work and whose contribution can be inferred from the documents or stylistic analysis of their illuminations, but also to their contemporaries. Besides the frequently mentioned Fabián Puléř, we can assume that Jan Taborský also collaborated with Matouš Ornys of Lindperk, Matyáš Hutský of Křivoklát, Ambrož Ledecký and, presumably, others. In this context, one part of the thesis is focused on engravings by Martin Schongauer, Albrecht Dürer, Bernard Salomon and on the domestic prints by George Melantrich the Elder, as these engravings, mostly woodcuts, served as patterns and inspiration for almost every Bohemian illuminator. Themes found in this type of manuscript are mostly based on Biblical stories, corresponding to the feasts of the liturgical year. In addition to these themes, the graduals contain many miniatures associated with various...
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Dose-response curves
Hezoučký, Martin ; Hlávka, Zdeněk (advisor) ; Maciak, Matúš (referee)
Title: Dose-response curves Author: Martin Hezoučký Department: Department of Probability and Mathematical Statistics Supervisor: doc. RNDr. Zdeněk Hlávka, Ph.D., Department of Probability and Mathematical Statistics Abstract: In this thesis, we deal with the process of research and development of new medical substances with a focus on statistical methods used to determine appropriate doses. For this purpose, we examine the dose-response relationship. First, we describe a typical procedure for the development of a new drug. Second, we focus in detail on the MCP-Mod method. Third, we propose a new method based on the theory of gradual change models. This approach tests whether the administration of the drug has a significant effect. If so, the dose with desired effect is estimated using an appropriate model. Specifically, we provide an esti- mate using linear, quadratic and Emax gradual change models. We also describe a construction of a confidence interval for the point of change and also for the dose with the desired effect. The advantage of the proposed method over the MCP-Mod is the determination of the confidence intervals. Finally, we apply the above mentioned methods to data from the U.S. Tox21 research program and compare the results based on several tested substances and clearly demonstrate the...
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Graduals from the Workshop of Jan Táborský of Klokotská Hora
Součková, Ema ; Royt, Jan (advisor) ; Brodský, Pavel (referee) ; Hlaváčková, Jana Hana (referee)
The dissertation focuses on the decoration of 16th century choral manuscripts. The first part is devoted to the person of Jan Táborský of Klokotská Hora (1499-1572) who was a scribe and an owner of a scribe manufactory, and to the most significant illuminators of the the 16th century who contributed to the decoration of songbooks in the Lands of the Bohemian Crown. Attention is given not only to the illuminators to whom Jan Táborský of Klokotská Hora assigned the work and whose contribution can be inferred from the documents or stylistic analysis of their illuminations, but also to their contemporaries. Besides the frequently mentioned Fabián Puléř, we can assume that Jan Taborský also collaborated with Matouš Ornys of Lindperk, Matyáš Hutský of Křivoklát, Ambrož Ledecký and, presumably, others. In this context, one part of the thesis is focused on engravings by Martin Schongauer, Albrecht Dürer, Bernard Salomon and on the domestic prints by George Melantrich the Elder, as these engravings, mostly woodcuts, served as patterns and inspiration for almost every Bohemian illuminator. Themes found in this type of manuscript are mostly based on Biblical stories, corresponding to the feasts of the liturgical year. In addition to these themes, the graduals contain many miniatures associated with various...
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The Work of Fabián Puléř
Svitáková, Kristina ; Hlaváčková, Jana Hana (advisor) ; Zlatohlávek, Martin (referee)
This thesis deals with Fabian Puléř, an illuminator who lived in the 2nd half of 16th century in Prague, and about his workshop in the Old Town. The main theme is the graduals and their fragments, which were made in his shop or are believed to be made there (the Metropolitan St. Vitus Temple Gradual, the Gradual of Čáslav, the Gradual of Žlutice, three illuminations from the collection of National Gallery in Prague, the two-part St. Valentine's Gradual from the Old Town, the fragments of Kaňkovský Gradual, the Gradual of Louny owned by Jan Táborský of Klokotská Hora, the Gradual of Český Brod), their description and cataloguization. Apart of critically rewieving the literation on the subject to this day, my thesis follows the life of Fabian Puléř regarding archival sources and also influences and impulses behind his work. It also contains crucial chapter about iconography of utraqistic musical manuscripts and about the litterateur brotherhoods, who ordered these hymnic books.
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