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Alimentary intake of fluoride in preschool children in dental caries prevention
Oganessian, Edgar ; Broukal, Zdeněk (advisor) ; Štípek, Stanislav (referee) ; Veverka, Jan (referee)
The primary prevention of dental caries includes the regular reduction of dental plaque, the adequate nutrition with reduced frequency of sugar intake and the application of topical and/or alimentary fluorides. The caries-protective effect of fluorides is based on the stabilization of demineralization/remineralization processes in the surface of teeth. The alimentary fluoride intake involves its nutritional sources, fluoride supplements when administered and unintentionally swallowed fluoride toothpastes. The fluoride intake, besides its verifiable and significant contribution to the control of cariogenic conditions in the oral cavity, brings some risk in the period of permanent teeth development. That is why the fluoride intake in childhood ought to be well set up and controlled for achieving the maximum benefit in caries reduction and for minimizing the risk for the enamel development. The assessment on fluoride content in its most significant nutritional sources and the model estimates of fluoride intake in preschool children have been conducted with the aim at contributing the solution of the benefit/risk strategy of fluoride caries prevention. The fluoride content was estimated in bottled waters for preschool children, in instant milk formulas, in herbal teas for children and in instant products of...
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Macrocyclic complexes with open coordination sphere
Jaroš, Adam ; Kubíček, Vojtěch (advisor) ; Gyepes, Róbert (referee)
The aim of this work was to synthesize and study acid-base and coordination properties of ligands bearing a neutral or negative charge on their pendant arms. Acid-base properties of two ligands and thermodynamic stability of their complexes with gallium, copper, and zinc ions were studied using potentiometry, UV-Vis and NMR. Solid state structure of one of the ligands and its complex with copper ion was studied using RTG structural analysis. Structure of complexes in solution was studied using methods of computational chemistry.
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Sperm strategies in rodents
Šandera, Martin ; Stopka, Pavel (advisor) ; Macholán, Miloš (referee) ; Sedláček, František (referee)
Rodents exhibit diverse biology, mating systems and diverse sperm morphology. Different levels of sperm competition have therefore been found in this group. Generally, it is accepted that sperm competition in animals causes the prolongation of sperm tails. However, what other sperm morphological adaptations in rodents are affected by sperm competition? Species-specific sexual selection likely optimizes sperm morphology. Sperm physiology, morphology and competition may be influenced, ultimately, by environmental factors. This Ph.D. thesis focuses on sperm competition in murine rodents. The thesis contains three research articles (including one as a submitted manuscript). In addition, another published article, partialy related to the topic of this thesis, is represented in the Appendix. The sperm morphology in rodents plays an important role in sperm competition. Longer tails and apical hooks are usually found in the species with relatively larger testes and with higher percentage of multiple paternity (i.e. rate of promiscuity), that is in species with the higher risk of sperm competition. The goal of the first study was to investigate the relationships between relative testis weight and sperm traits (apical hook and tail lengths and variance in this traits). The apical hook length was positively...
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Alimentary intake of fluoride in preschool children in dental caries prevention
Oganessian, Edgar ; Broukal, Zdeněk (advisor) ; Štípek, Stanislav (referee) ; Veverka, Jan (referee)
The primary prevention of dental caries includes the regular reduction of dental plaque, the adequate nutrition with reduced frequency of sugar intake and the application of topical and/or alimentary fluorides. The caries-protective effect of fluorides is based on the stabilization of demineralization/remineralization processes in the surface of teeth. The alimentary fluoride intake involves its nutritional sources, fluoride supplements when administered and unintentionally swallowed fluoride toothpastes. The fluoride intake, besides its verifiable and significant contribution to the control of cariogenic conditions in the oral cavity, brings some risk in the period of permanent teeth development. That is why the fluoride intake in childhood ought to be well set up and controlled for achieving the maximum benefit in caries reduction and for minimizing the risk for the enamel development. The assessment on fluoride content in its most significant nutritional sources and the model estimates of fluoride intake in preschool children have been conducted with the aim at contributing the solution of the benefit/risk strategy of fluoride caries prevention. The fluoride content was estimated in bottled waters for preschool children, in instant milk formulas, in herbal teas for children and in instant products of...
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