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Expert System for Assessing the Type of Arrhythmia during Catheter Radiofrequency Ablation of Cardiac Arrhythmias
Šromová, Michaela ; Provazník, Ivo (referee) ; Sekora, Jiří (advisor)
The theoretical part of the thesis contains a brief description of the anatomy and electrophysiology of the heart, as well as both, surface and intracardiac electrocardiograms. The thesis also describes the different types of cardiac tachycardias, their differential diagnosis and what is known as The Expert System. The practical section of the thesis notes and outlines the tree diagrams, and additionally describes various software solutions of The Expert System. Further, the thesis includes the classification of the heart rhythm, using The Expert System method with three typical tachycardia cases, and including a list of questions asked by The Expert System to the user. Answers to all questions asked are being assessed in the text, as well as illustrated in submitted examples of intracardiac ECG recordings. The Expert System has been verified during a series of catheterization procedures on 26 patients (where the evaluated cardiac rhythm was 34). The classication of the type of heart rhythm (per The Expert System) when comparing the results with the doctors coincided in 100 % of tested cases.
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Differential Diagnostics of Anaemias from the Morphological Point of View
KLIMENTOVÁ, Michaela
Anaemia is considered to be a worldwide disease and it remains to be a topical one. This thesis tries to stress the importance of correct diagnosis of anaemia, without which correct and effective treatment cannot be adjusted. Although the number of people with anaemia is increasing, a large proportion are unaware of their disease, have not been diagnosed with it and therefore do not treat it. To diagnose anaemia is not difficult, however, differential diagnosis is the key to diagnose it correctly. A great contribution to the differential diagnosis is the description of erythrocyte indices that can be used to determine the exact type of anaemia and their subsequent use in differential diagnosis. The main objective of this bachelor thesis, entitled "Morphological Differential Diagnosis of Anaemia", is the statistical evaluation of the incidence of different types of anaemia, differentiated based on the erythrocyte morphology. Within the practical part of the thesis, blood counts were analysed on an automatic haematology analyser and then the data from the examinations were statistically processed. Excel was used to process all the data. The results of the statistical processing were entered into tables and graphs. Before the statistical processing, 3 hypotheses were defined and tested using a chi-square test which resulted in a level of significance (p). For all three hypotheses, the resulting level of significance was <5%, meaning that all null hypotheses were rejected and in all cases the alternative hypothesis was accepted. Surprisingly, macrocytic anaemia was more frequent than microcytic anaemia in the dataset (20 % of all types of anaemia versus 10 %), but as expected, hypochromic anaemia was more frequent than hyperchromic anaemia (17.39 % of all types of anaemia versus 5.65 %). Normocytic normochromic anaemia was the most represented anaemia in the dataset (62.61 % of types of anaemia). The results obtained from this study may be used for research purposes or as a source of information.
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Using the MMPI-2 in Differential Diagnostic of Asperger's Syndrome and Schizofrenia
Adámková, Jana ; Soukupová, Tereza (advisor) ; Goldmann, Petr (referee)
The main target of this study is to identify the scales in MMPI-2 which could help the differential diagnostic process between Asperger's syndrome and schizophrenia. Adult persons with Asperger's syndrome and adult persons with schizophrenia were examined. The study has a quantitative character, concretely data mining, which offers generating and verifying hypothesis. The results show that configuration of heights of specific scales can be crucial in distinguishing between Asperger's syndrome and schizophrenia. In the concrete we expect increase in 0Si, Sc1, Pa2 and OBS along with medial T-scores in Sc6, Pa1, Psyc and Biz in protocols of people with Asperger's syndrome. People with schizophrenia have increased T-scores in Sc6, Pa1, Psyc and Biz. KEY WORDS Asperger's syndrome Schizophrenia Differential diagnostic Adulthood MMPI-2
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Proposal of therapeutic materials for clients diagnosed with aphasia
Maňáková, Kateřina ; Durdilová, Lucie (advisor) ; Klenková, Jiřina (referee)
The thesis with the topic of proposing new therapeutic materials for clients diagnosed with aphasia brings more profound understanding of separate field of speech therapy, which is aphasiology. The first part of the thesis introduces the theoretical basis to the issues of aphasia, concentrates on fundamental definition of aphasia, etiology and symptomatology. Moreover, the thesis describes the possibilities of aphasia therapy and lastly, it covers the differential diagnostics of aphasia. The second part of the thesis covers in detail the Boston Classification System of Aphasia, introduces to the reader the foundations that were the basis for the propositions of the therapeutic materials. The second part describes in detail the very process of designing therapeutic materials in general and it also provides concrete propositions of such materials with possible applications. The appendix includes examples of proposed materials, both theoretically explained and physically created for the reader to examine.
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Advances in the diagnosis and treatment of Parkinson's disease
Koťátková, Hana ; Nejmanová, Iveta (advisor) ; Herink, Josef (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Biological and Medical Sciences Author: Hana Koťátková Supervisor: PharmDr. Iveta Nejmanova, Ph.D. Form: Bachelor thesis Field of study: Medical Bioanalytics Title: Advances in the diagnosis and treatment of Parkinson's diseases The aim of the work: The aim is to clearly write current and developed diagnostic and treatment procedures for Parkinson's disease. The retrieved and collected information is analyzed and summarized. Main goals: The topic of this bachelor thesis is Parkinson's disease, especially its diagnosis and therapy. The introductory chapters deal with Parkinsonism, the epidemiology and etiopathogenesis of Parkinson's diseases, as well as the clinical symptoms. Diagnosis and therapy occupy the largest part of this bachelor thesis. Clinical diagnostics no longer focuses only on motor symptoms, but also includes non-motor ones. Various diagnostic criteria, scales and tests that are currently used will be mentioned. This bachelor thesis also includes a chapter on biomarkers of Parkinson's disease, because there is great potential. The chapters about therapy mention current pharmacotherapies, their development, neurosurgical treatment and the effects of immunotherapy and gene therapy. Conclusion: From the...
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Differential diagnosis of abdominal pain in pre-hospital emergency care for adults
KLINEROVÁ, Eliška
This bachelor thesis solves the problem of differential diagnosis of abdominal pain in pre-hospital emergency care for adults where abdominal pain includes a very wide range of possible causes and illnesses. If proper and rapid diagnosis is determined in pre-hospital emergency care, it will greatly facilitate and speed up subsequent treatment. The thesis consists of two parts, a theoretical and a research one. The theoretical deals with the concept of pain, the importance of physical examination, the carefulness of anamnesis and the differentiation of pain according to the localization (right and left upper quadrant, right and left lower quadrant), other possible causes and pharmacological therapy. The practical part was realized in a qualitative form using semi-structured questionnaires. The aim was to map the most common primary diagnoses of abdominal pain and follow-up procedures and investigative methods of emergency rescue workers in pre-hospital emergency care. The research was conducted in March and April 2018 with the health rescuers of the Vysočina Region. For clarity, the data obtained was divided into categories, processed into tables and further compared. Research has shown that the procedure for examining a patient with abdominal pain is not ideal, often neglected important information that needs to be identified as soon as possible from the onset of the problems and including their further development. Therefore, a possible algorithm for patient's abdominal pain assessment in pre-hospital inadequate care has been proposed for possible follow-up in practice, containing all the important information that needs to be found in PNP and then handed over to the target hospital facility.
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Physiotherapy approaches aimed at management of talipes planus. Subtitle: Diagnosis and Therapy
Koukalová, Aneta ; Konopáčová, Eva (advisor) ; Novotná, Marie (referee)
Title: Physiotherapy approaches aimed at management of talipes planus, subtitle: diagnosis and therapy Abstract: Bachelor thesis is aimed on the diagnosis of talipes planus and physiotherypy methods suitable for patients with the untreated talipes planus. Talipes planus causes a lot of musculoskeletal problems so is important to start with diagnosis and therapy early. The theoretical part contains anatomy of the foot, differential diagnosis of the talipes planus and its causes, symptoms and consequences. Farther is described here influence of the talipes planus to our posture. The main chapters of the theoretical part are diagnostic methods and therapy aimed on the talipes planus. The practical part includes casuistries of free patients who have at least type of untretaed talipes planus. The casuistries contain case history, input and output kinesiology analysis, a detail description of the therapy and total evalution and comparison of the effect of physiotherapy between patients. Key words: talipes planus, physiotherapy, differencial diagnosis, orthopedic shoes, ortopedic insoles, instrumental examination, posture
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Using the MMPI-2 in Differential Diagnostic of Asperger's Syndrome and Schizofrenia
Adámková, Jana ; Soukupová, Tereza (advisor) ; Goldmann, Petr (referee)
The main target of this study is to identify the scales in MMPI-2 which could help the differential diagnostic process between Asperger's syndrome and schizophrenia. Adult persons with Asperger's syndrome and adult persons with schizophrenia were examined. The study has a quantitative character, concretely data mining, which offers generating and verifying hypothesis. The results show that configuration of heights of specific scales can be crucial in distinguishing between Asperger's syndrome and schizophrenia. In the concrete we expect increase in 0Si, Sc1, Pa2 and OBS along with medial T-scores in Sc6, Pa1, Psyc and Biz in protocols of people with Asperger's syndrome. People with schizophrenia have increased T-scores in Sc6, Pa1, Psyc and Biz. KEY WORDS Asperger's syndrome Schizophrenia Differential diagnostic Adulthood MMPI-2
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Proposal of therapeutic materials for clients diagnosed with aphasia
Maňáková, Kateřina ; Durdilová, Lucie (advisor) ; Klenková, Jiřina (referee)
The thesis with the topic of proposing new therapeutic materials for clients diagnosed with aphasia brings more profound understanding of separate field of speech therapy, which is aphasiology. The first part of the thesis introduces the theoretical basis to the issues of aphasia, concentrates on fundamental definition of aphasia, etiology and symptomatology. Moreover, the thesis describes the possibilities of aphasia therapy and lastly, it covers the differential diagnostics of aphasia. The second part of the thesis covers in detail the Boston Classification System of Aphasia, introduces to the reader the foundations that were the basis for the propositions of the therapeutic materials. The second part describes in detail the very process of designing therapeutic materials in general and it also provides concrete propositions of such materials with possible applications. The appendix includes examples of proposed materials, both theoretically explained and physically created for the reader to examine.
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