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Methamphetamine toxic psychosis from the perspective of a client
Jarmarová, Anna ; Minařík, Jakub (advisor) ; Drbohlavová, Barbora (referee)
The Bachelor's thesis deals with methamphetamine induced psychosis. The theoretical part describes not only the effects of methamphetamine on the mental state of clients, but also defines the concept of methamphetamine induced psychosis. It divides psychoses into endogenous and substance-induced psychosis. It emphasizes the positive and negative symptoms of this disease and interprets a number of studies dealing with neurobiology of toxic psychosis and genetic predisposition. The aim of this work is to describe toxic psychosis among long-term methamphetamine users as they perceive whether the relationship between intensity, regularity of use, and method of application of methamphetamine with toxic psychosis can be established. Whether the client is aware of the course of toxic psychosis and whether the psychotic episode affects the client's intensity of use, or overall abstinence from drugs. The survey was conducted on a sample of 6 users - 3 abstainers and 3 active users. To get qualitative data I chose a combination of several methods, observation, record sheet and semi-structured interview. The conversations were recorded on the recording equipment and the audio recording was further transcribed in MS Word. The systematization of the qualitative data was done by sorting data according to...
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PHARMACOTERAPEUTIC INTERVENTIONS IN ADDICTION TREATMENT
Kozinski, Jan ; Minařík, Jakub (advisor) ; Oktábec, Zbyněk (referee)
Drug dependence is one of the most common psychiatric diagnosis besides with affective disorders and anxiety disorders. Drug abuse may entail many somatic and psychiatric comorbidities which complicate treatment and substantially worsen its prognosis. Allthough the main reason of keeping dependence behaviour are maladaptive behavioural patterns, on the cell level there are mainly pathophysiological processes in the central nervous systém. Similarly, it can be supposed that centre of treatment lies in psychotherapy, nevertheless parallel medication may significantly reduce subjective difficulties connected with abstinence from drug, which are common reason from treatment terminating from the side of patient. In the urgent addictology, or acute psychiatry it is possible to meet with situations, when psychotherapeutic techniques have only limited effectiveness. It is possible to use for example de-escalate approach with anxious patient that is intoxicated by cannabinoids or halucinogens, but it has no efficacy in the case of life-threatening acute intoxication by anticholinergics, opioids or tranquillisers. Similarly, in the case of acute withdrawal syndrome after long abuse of drugs with strong physical dependence, such as alcohol or benzodiazepines may physician almost exclusively rely on...
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The phenomenon of alcoholism and opportunities for social work
Maternová, Marcela ; Žáčková, Hana (advisor) ; Krahulcová, Beáta (referee)
This diploma thesis explores the phenomenon of formation and development of alcohol dependence. In the first series focuses on the historical description, which demonstrates considerable anchored in the life of our ancestors already. It also defines the concept of addiction, its causes and consequences, whether psychological, medical or social. Its objective is to describe the possibilities of social work in this phenomenon. defines therefore primarily targets and understanding of social work and consequently specifics of client alcoholism. An important element is the role of the social worker in the client's motivation to change, which uses Nešpor's model of spontaneous changes in motivation. Then, on the basis of available social services selects several most suitable, which can help to improve the client's situation. Has an essential role in this issue also primary prevention, ie it discusses the methodology, target groups, focusing on adolescents and the focus is on the firm role of the family. Finally contains some official documents on primary prevention, which are discussed current issues of primary prevention practice and subsequent survey, mapping aspect of social workers on the incidence risk of alcohol dependence among adolescents attending social facilities.
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Toxicity of freely available analgesics in relation to human health
VODVÁŘKA, Stanislav
Analgesics represent a large group of medicines which is used for suppresing subjectively perceived pain. Analgesics can be divided into two large groups, opioids and non-opioids. Some of the non-opioids can be used as anti-inflammatory and/or antipyretics as well. All non-opioids influence metabolism of prostaglandins. Diverse group of non-opioid analgesics is available in Czech pharmacies as prescription medicines or for sale over the counter. The aim of this work is mainly to assess the toxicity of over-the-counter analgesics and to find out the frequency of fatal intoxications caused by these analgesics in the Czech Republic and abroad. A list of peroral over-the-counter analgesics was created. A partial analysis of data from medical judicial departments of regional hospitals in the Czech Republic was performed in order to obtain total number of deaths caused by overdosing with these drugs. Using ÚZIS the number of deaths was extracted from information system Deceased. These logged deaths were caused only by acute intoxication with analgesics and were chosen on basis of precisely defined combinations of diagnostic codes (MKN10). Results were then expanded by similar enumeration from the National register of hospitalized, by which we specified the amount of intoxications where patients survived. Overall case report was evaluated from processed information. The number of deaths caused by analgesics and commonly misused addictive substances were compared by which the second hypothesis was clarified. The data was obtained from Annual reports about substance misuse and 6 years were compared in total. Identified risk of analgesic in Czech Republic was compared with registered cases of overdosing in world. Data used for comparing were gained from analysis of world literature. During the years 2006 ? 2011, 53 deaths and 2024 hospitalizations in the Czech Republic were caused by acute intoxication as a result of overdosing with mentioned medication. Our first hypotesis can be confirmed on the basis of these numbers, and therefor it can be said that over-the-counter medicines used for suppressing pain can cause death. On the basis of analysis of world literature a certain risk is seen in fact that these analgesics ? mainly paracetamol ? are often linked with suicides. For instance in United Kingdom thousands of cases of self-harm are caused by overdosing with paracetamol. In USA 16 500 deaths are thought to be caused by NSAIDS and 1600 acute liver failure incidents are caused by overdosing with paracetamol annualy. Illegal drugs caused 253 intoxications during the years 2006 -2011 compared to 53 cases of deaths caused by overdosing by analgesics. Annual reports about substance misuse report that deaths caused by illegal drugs are more common than deaths caused by over-the-counter analgesics in the Czech Republic. There remains a question: What percentage of analgesics intoxications, where patient survived or not, is caused only by over-the-counter analgesics without any other cause.
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