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Assessment of facial morphology in patients with orofacial clefts in relation to surgical protocols
Moslerová, Veronika ; Velemínská, Jana (advisor) ; Dostálová, Taťjana (referee) ; Katina, Stanislav (referee)
The presented thesis summarizes the results of research on craniofacial morphology in patients with facial cleft defects in relation to therapeutic approaches (Caganova et al., 2014; Dadáková et al., 2016; Hoffmannova et al., 2016; Hoffmannova et al., 2018; Moslerová et al., 2018). The effect of therapy in individuals with pathological growth disorders cannot be evaluated without detailed auxological studies of control subjects whose facial morphology, longitudinal changes, or manifestations of sexual dimorphism were evaluated upon similar methodology (Koudelová et al. 2015). Therefore, the thesis was conceived as a volume of six publications complemented with a general synthetic introduction into the area of study. Together, the thesis includes probands in a broad age spectrum from birth to 15 years with a total of 294 facial 3D scans, 36 tele-X-ray face images, 3D scans of 112 gypsum palate castings. The methods of geometric morphometry and multidimensional statistics prevail in the assessment. The main clinical part of the thesis deals with the influence of two types of surgery on the facial growth and development of patients with cleft palate, namely secondary spongioplasty (SS) and neonatal cheiloplasty (NCH). Neonatal cheiloplasty (NCH) is the surgery whose effects were studied from several...
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Neonatal cheiloplasty as the first surgery in patients with orofacial clefts, its benefits and possible risks
Kordačová, Karolína ; Velemínská, Jana (advisor) ; Hoffmannová, Eva (referee)
Neonatal cheiloplasty is the first plastic surgery performed in patients with orofacial clefts, usually carried out at the age of 1 to 8 days. A modified protocol for standard cheiloplasty, performed at the age of 3 to 6 months, is used. Neonatal cheiloplasty is currently a predominant method for lip surgery in cleft lip patients in the Czech Republic. Advantages of this method are better scar healing associated with better aesthetic results, reduced psychological and sociological pressure on the family and the infant, better quality of feeding and breastfeeding, and possibly reduced need of secondary repair. There is no documented direct negative consequence of the early timing. Nevertheless, possible risks can be associated with general anaesthesia at such low age, as it could have a negative effect on future IQ of the patient, and a possibility of reduced growth and development of jaws and impaired facial aesthetic outcomes. Further, compared to classical cheiloplasty, early surgery is more expensive and demands higher skills and experiences of the surgeon and the whole team performing the procedure. Main goals of this work were to evaluate the benefits and possible risks of neonatal cheiloplasty as the first surgery performed in patients with orofacial clefts using available studies on this...
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Assessment of facial morphology in patients with orofacial clefts in relation to surgical protocols
Moslerová, Veronika
The presented thesis summarizes the results of research on craniofacial morphology in patients with facial cleft defects in relation to therapeutic approaches (Caganova et al., 2014; Dadáková et al., 2016; Hoffmannova et al., 2016; Hoffmannova et al., 2018; Moslerová et al., 2018). The effect of therapy in individuals with pathological growth disorders cannot be evaluated without detailed auxological studies of control subjects whose facial morphology, longitudinal changes, or manifestations of sexual dimorphism were evaluated upon similar methodology (Koudelová et al. 2015). Therefore, the thesis was conceived as a volume of six publications complemented with a general synthetic introduction into the area of study. Together, the thesis includes probands in a broad age spectrum from birth to 15 years with a total of 294 facial 3D scans, 36 tele-X-ray face images, 3D scans of 112 gypsum palate castings. The methods of geometric morphometry and multidimensional statistics prevail in the assessment. The main clinical part of the thesis deals with the influence of two types of surgery on the facial growth and development of patients with cleft palate, namely secondary spongioplasty (SS) and neonatal cheiloplasty (NCH). Neonatal cheiloplasty (NCH) is the surgery whose effects were studied from several...
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Neonatal cheiloplasty as the first surgery in patients with orofacial clefts, its benefits and possible risks
Kordačová, Karolína ; Velemínská, Jana (advisor) ; Hoffmannová, Eva (referee)
Neonatal cheiloplasty is the first plastic surgery performed in patients with orofacial clefts, usually carried out at the age of 1 to 8 days. A modified protocol for standard cheiloplasty, performed at the age of 3 to 6 months, is used. Neonatal cheiloplasty is currently a predominant method for lip surgery in cleft lip patients in the Czech Republic. Advantages of this method are better scar healing associated with better aesthetic results, reduced psychological and sociological pressure on the family and the infant, better quality of feeding and breastfeeding, and possibly reduced need of secondary repair. There is no documented direct negative consequence of the early timing. Nevertheless, possible risks can be associated with general anaesthesia at such low age, as it could have a negative effect on future IQ of the patient, and a possibility of reduced growth and development of jaws and impaired facial aesthetic outcomes. Further, compared to classical cheiloplasty, early surgery is more expensive and demands higher skills and experiences of the surgeon and the whole team performing the procedure. Main goals of this work were to evaluate the benefits and possible risks of neonatal cheiloplasty as the first surgery performed in patients with orofacial clefts using available studies on this...
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Assessment of facial morphology in patients with orofacial clefts in relation to surgical protocols
Moslerová, Veronika ; Velemínská, Jana (advisor) ; Dostálová, Taťjana (referee) ; Katina, Stanislav (referee)
The presented thesis summarizes the results of research on craniofacial morphology in patients with facial cleft defects in relation to therapeutic approaches (Caganova et al., 2014; Dadáková et al., 2016; Hoffmannova et al., 2016; Hoffmannova et al., 2018; Moslerová et al., 2018). The effect of therapy in individuals with pathological growth disorders cannot be evaluated without detailed auxological studies of control subjects whose facial morphology, longitudinal changes, or manifestations of sexual dimorphism were evaluated upon similar methodology (Koudelová et al. 2015). Therefore, the thesis was conceived as a volume of six publications complemented with a general synthetic introduction into the area of study. Together, the thesis includes probands in a broad age spectrum from birth to 15 years with a total of 294 facial 3D scans, 36 tele-X-ray face images, 3D scans of 112 gypsum palate castings. The methods of geometric morphometry and multidimensional statistics prevail in the assessment. The main clinical part of the thesis deals with the influence of two types of surgery on the facial growth and development of patients with cleft palate, namely secondary spongioplasty (SS) and neonatal cheiloplasty (NCH). Neonatal cheiloplasty (NCH) is the surgery whose effects were studied from several...
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