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Modeling spatial interactions on the example of the regional cities
Zelenka, Jaroslav ; Marada, Miroslav (advisor) ; Chmelík, Jakub (referee)
Management and planning of transportation is becoming more important in terms of continuously growing intensity of spatial interactions, which are still mostly realized through transport networks. That's why we can deal with this specific problem of transportation geography using for example spatial interactions modeling. The general aim of the thesis is modeling of spatial interactions and their subsequent comparison with real flows by using calibration in order to predicate the future value of flows taking the planned changes in the transport network in consideration. The main tool used to achieve the goal of the thesis is the gravity model which was applied on the example of regional capitals in the Czech Republic. Based on accomplishments we may say, that centers with lower significance of monitored relations are characterized by further location towards most centers, small number of inhabitants, low intensity of model interactions and lower values of transport intensities with neighboring centers. With the center growth itself, its range of interactions with other centers grows as well. Key Words: spatial interactions modeling, gravity model, model interaction, transport intensity, regional capitals
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Enterohepatic circulation of bilirubin
Zelenka, Jaroslav ; Vítek, Libor (advisor) ; Entlicher, Gustav (referee) ; Červinková, Zuzana (referee)
Bilirubin is a main physiological product of heme degradation possessing important antioxidant and antiinflammatory properties. On the other hand, it could be neurotoxic during severe unconjugated hyperbilirubinemia combined with insufficiency of blood-brain barrier (neonatal jaundice). It is secreted from the body via bile and is further metabolized in the intestine. Part of the substance is reduced to urobilinoids, part is adsorbed to the intestinal content and some part could be reabsorbed back to the systemic circulation. This enterohepatically and enterosystemically circulating fraction varies in size depending on the rate of bilirubin secretion, solubility in the intestine and intensity of its intestinal metabolism. Under specific circumstances, EHC and ESC may significantly increase serum and bile bilirubin levels and influence physiological as well as pathological processes occuring in the body. Among the most important is the protective elevation of UCB levels in Gilbert syndrome subjects and dangerous increase in severity of neonatal jaundice. In the presented thesis, the mechanisms affecting EHC and ESC of bilirubin and tools for further research in BP metabolism were investigated. The solubility of intestinal UCB is strongly decreased by addition of divalent cations. However, such approach to...
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Struggle for Šwidnica-Jawor duchy under the reign of the Luxembourg dynasty
Zelenka, Jaroslav ; Vorel, Petr (referee) ; Bobková, Lenka (advisor)
Shire of successors of Boleslav I. of Svídnice (Schweidni tz, Swidnica) represents an anomaly in the history of Silesia. Dukes of this branch of Silesian house of Piasts were thoroughly refusing to became vassals of czech king by profi ting of their rel a tionship wi th Wi ttelsbachs, Habsbourgs, Anj ous, as well as wi th polish king Casimir III of Poland. Bolek II of Svidnice was the most powerfull adversary of Luxembourgs. Even by using a military force, John of Luxembourg couldn't break his opposition. Situation had radically changed by the Treaty of Namyslov (Namslau, Namyslów) between Charles IV and Casimir III of Poland in 1348. By this treaty, polish king officially renounced to support his nephew. Charles IV was aware of quali ties of Bolek II and he didn't want to loose him by blessing his ego. So he didn't choose the way of violence, but he gave him a lot of privileges to "buy" his support. Czech king offered to Bolek II the alliance that he couldn't refuse. By this alliance he allowed Bolek to fulfill his power ambi tions what should have never been done, if he had remained adversary of Luxembourg's. Bolek I I of Svidnice was capable to profit from this extraordinary favor until his death. He succeeded to j oin to his shire numerous territories and assure some important economic privileges for...
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The Impact of External Events on the Market Capitalization of Companies
Zelenka, Jaroslav ; Krabec, Tomáš (advisor) ; Veselá, Jitka (referee)
This diploma thesis analyses the relationship between external events (i.e. events with impact within the Czech Republic which cannot be influenced by local firms) and the value of market capitalization of companies on Prague Stock Exchange. The analysis of the 1994 to 2012 time series showed that even the most important political, economical and other events specific for the Czech Republic only have marginal impacts on values of companies on the Czech stock market. The impacts of corporate events proved to have much stronger such effects. The most advisable investment recommendation thus seems to be to ignore external events when deciding in which stocks to invest.
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Effects of Insider Trading Regulation
Zelenka, Jaroslav ; Bolcha, Peter (advisor) ; Mičúch, Marek (referee)
This thesis analyses the relationship between insider trading regulation (broadly interpreted) and equity costs of firms on data from the Chinese, South African and Russian capital markets covering the years from 1995 to 2011. Time series analysis showed -- as expected -- that stock markets in each of the countries react in specific ways: E.g. none of the regulatory measures proved effective in decreasing the equity costs in the case of South Africa. Analysis of the Chinses and Russian data showed, however, a possible common feature of the participants on the two markets. It seems that these markets react to mere signals of upcoming regulatory measures rather than on these measures themselves. This interpretation of the results is thus in line with the rational expectations hypothesis.
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Constitutional Analysis of the Lisbon Treaty
Zelenka, Jaroslav ; Hudík, Marek (advisor) ; Skopeček, Jan (referee)
This work applies the constitutional analysis method on the evaluation of the EU constitutional setting's change after the possible approval of the Lisbon Treaty. We will focus on the part of the Treaty that has an impact on the character of the legislation connected with commodity taxation. Specifically, we will analyze the change of the voting rules of the Council and the change of the constitutional cognizance of the Council. After we draw the parallel between the Council and the revenue-maximizing Leviathan, we will be able to advocate for the conclusion of our analysis which is that the base and rates of the commodity taxation will change to the disadvantage of the taxpayer after the approval of the Treaty.
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