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Tools for Environment for the Simulation of Communication
Mikuš, Peter ; Trchalík, Roman (referee) ; Očenášek, Pavel (advisor)
Communication between devices should be based on predefined rules. These rules are called communication protocols. In this master thesis I am concerned with communication protocols, specially security protocols. Their design demand specialized tools, that will provide interactive simulations and security testing. I have described each of these tools in detail and mentioned about their properties, their pros and cons. In available tools I have implemented security protocols. The result is set of demonstration tasks that are usable in network courses at FIT VUT
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Synchronization of Email Addresses
Mikuš, Peter ; Ráb, Jaroslav (referee) ; Matoušek, Petr (advisor)
Synchronization represents the process of keeping consistency of data stored in one or more locations. There are several applications with this function available on the market. We expect from applications to synchronize data quickly, reliable and safely. In my work I am concerned with the ways of storing email addresses by mail applications and available resources of file synchronization. As the result I will make and implement functional model. The purpose and motivation of this work is to create own solution, which will perform the synchronization of email addresses.
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Application of modern separation techniques in the analysis of biological material
Červinková, Barbora ; Solich, Petr (advisor) ; Mikuš, Peter (referee) ; Štěrbová, Petra (referee)
Charles University, Faculty of Pharmacy in Hradec Králové Department of Department of Analytical Chemistry Candidate Mgr. Barbora Červinková Supervisor prof. RNDr. Petr Solich, CSc. Title of Doctoral Thesis Application of modern separation techniques in the analysis of biological material The presented dissertation is focused on development, optimization and validation of new extraction procedures and chromatographic methods for determination of vitamins A and E, inflammation biomarkers, DNA and RNA oxidative stress products in biological matrices. In the theoretical part of this work selected analytes and possibility of their determination in biological materials are described. Moreover, modern trends in liquid chromatography and bioanalytical validation guidelines are included. In this part, special attention is focused on sample handling, transport and pre- treatment. The second part is focused on published methods and divided into two sections. The first section comments published developed analytical methods. As first method, determination of lipophilic vitamins in human serum by miniaturized liquid-liquid extraction with subsequent separation on fluorinated stationary phase using UHPLC system with fluorescent detection in 4 min is discussed. Thereafter, determination of creatinine, DNA and...
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Development of HPLC methods for analytical evaluation of drug products and model studies of natural degradation of drug residues.
Nejedlý, Tomáš ; Klimeš, Jiří (advisor) ; Karlíček, Rolf (referee) ; Mikuš, Peter (referee)
Charles University, Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Chemistry and Pharmaceutical Analysis Candidate Mgr. Tomáš Nejedlý Supervisor prof. RNDr. Jiří Klimeš, CSc. Title of Doctoral Thesis Development of HPLC methods for analytical evaluation of drug products and model studies of natural degradation of drug residues The presented doctoral thesis describes two areas of pharmaceutical analysis. The first part is focused on development of validated chromatographic methods for pharmaceutical-analytical assesment of drug products and their rutine use in quality control laboratories. The second part deals with the very actual topic of environmental analysis and residues of pharmaceutical substances in sewage and surface water. The first developed method is suitable for quality evaluation of cream dosage forms containing aciclovir active substance. This method is suitable for assay of active substance and its three related substances. In addition it is validated for assay of preservatives contained in cream base. The second chromatographic method is developed for determination of tablets containing 1 mg of risperidone antipsychotic drug per tablet. This method was validated for active substance assay and the four mostimportant pharmacopoeial impurities. The last method is...
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Application of modern separation techniques in the analysis of biological material
Červinková, Barbora ; Solich, Petr (advisor) ; Mikuš, Peter (referee) ; Štěrbová, Petra (referee)
Charles University, Faculty of Pharmacy in Hradec Králové Department of Department of Analytical Chemistry Candidate Mgr. Barbora Červinková Supervisor prof. RNDr. Petr Solich, CSc. Title of Doctoral Thesis Application of modern separation techniques in the analysis of biological material The presented dissertation is focused on development, optimization and validation of new extraction procedures and chromatographic methods for determination of vitamins A and E, inflammation biomarkers, DNA and RNA oxidative stress products in biological matrices. In the theoretical part of this work selected analytes and possibility of their determination in biological materials are described. Moreover, modern trends in liquid chromatography and bioanalytical validation guidelines are included. In this part, special attention is focused on sample handling, transport and pre- treatment. The second part is focused on published methods and divided into two sections. The first section comments published developed analytical methods. As first method, determination of lipophilic vitamins in human serum by miniaturized liquid-liquid extraction with subsequent separation on fluorinated stationary phase using UHPLC system with fluorescent detection in 4 min is discussed. Thereafter, determination of creatinine, DNA and...
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Development of HPLC methods for analytical evaluation of drug products and model studies of natural degradation of drug residues.
Nejedlý, Tomáš ; Klimeš, Jiří (advisor) ; Karlíček, Rolf (referee) ; Mikuš, Peter (referee)
Charles University, Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Chemistry and Pharmaceutical Analysis Candidate Mgr. Tomáš Nejedlý Supervisor prof. RNDr. Jiří Klimeš, CSc. Title of Doctoral Thesis Development of HPLC methods for analytical evaluation of drug products and model studies of natural degradation of drug residues The presented doctoral thesis describes two areas of pharmaceutical analysis. The first part is focused on development of validated chromatographic methods for pharmaceutical-analytical assesment of drug products and their rutine use in quality control laboratories. The second part deals with the very actual topic of environmental analysis and residues of pharmaceutical substances in sewage and surface water. The first developed method is suitable for quality evaluation of cream dosage forms containing aciclovir active substance. This method is suitable for assay of active substance and its three related substances. In addition it is validated for assay of preservatives contained in cream base. The second chromatographic method is developed for determination of tablets containing 1 mg of risperidone antipsychotic drug per tablet. This method was validated for active substance assay and the four mostimportant pharmacopoeial impurities. The last method is...
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Application of modern separation techniques in the analysis of biological material
Červinková, Barbora ; Solich, Petr (advisor) ; Mikuš, Peter (referee) ; Štěrbová, Petra (referee)
Charles University, Faculty of Pharmacy in Hradec Králové Department of Department of Analytical Chemistry Candidate Mgr. Barbora Červinková Supervisor prof. RNDr. Petr Solich, CSc. Title of Doctoral Thesis Application of modern separation techniques in the analysis of biological material The presented dissertation is focused on development, optimization and validation of new extraction procedures and chromatographic methods for determination of vitamins A and E, inflammation biomarkers, DNA and RNA oxidative stress products in biological matrices. In the theoretical part of this work selected analytes and possibility of their determination in biological materials are described. Moreover, modern trends in liquid chromatography and bioanalytical validation guidelines are included. In this part, special attention is focused on sample handling, transport and pre- treatment. The second part is focused on published methods and divided into two sections. The first section comments published developed analytical methods. As first method, determination of lipophilic vitamins in human serum by miniaturized liquid-liquid extraction with subsequent separation on fluorinated stationary phase using UHPLC system with fluorescent detection in 4 min is discussed. Thereafter, determination of creatinine, DNA and...
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Application of modern separation techniques in the analysis of biological material
Červinková, Barbora ; Solich, Petr (advisor) ; Mikuš, Peter (referee) ; Štěrbová, Petra (referee)
Charles University, Faculty of Pharmacy in Hradec Králové Department of Department of Analytical Chemistry Candidate Mgr. Barbora Červinková Supervisor prof. RNDr. Petr Solich, CSc. Title of Doctoral Thesis Application of modern separation techniques in the analysis of biological material The presented dissertation is focused on development, optimization and validation of new extraction procedures and chromatographic methods for determination of vitamins A and E, inflammation biomarkers, DNA and RNA oxidative stress products in biological matrices. In the theoretical part of this work selected analytes and possibility of their determination in biological materials are described. Moreover, modern trends in liquid chromatography and bioanalytical validation guidelines are included. In this part, special attention is focused on sample handling, transport and pre- treatment. The second part is focused on published methods and divided into two sections. The first section comments published developed analytical methods. As first method, determination of lipophilic vitamins in human serum by miniaturized liquid-liquid extraction with subsequent separation on fluorinated stationary phase using UHPLC system with fluorescent detection in 4 min is discussed. Thereafter, determination of creatinine, DNA and...
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|
|
Synchronization of Email Addresses
Mikuš, Peter ; Ráb, Jaroslav (referee) ; Matoušek, Petr (advisor)
Synchronization represents the process of keeping consistency of data stored in one or more locations. There are several applications with this function available on the market. We expect from applications to synchronize data quickly, reliable and safely. In my work I am concerned with the ways of storing email addresses by mail applications and available resources of file synchronization. As the result I will make and implement functional model. The purpose and motivation of this work is to create own solution, which will perform the synchronization of email addresses.
|
|
|
Tools for Environment for the Simulation of Communication
Mikuš, Peter ; Trchalík, Roman (referee) ; Očenášek, Pavel (advisor)
Communication between devices should be based on predefined rules. These rules are called communication protocols. In this master thesis I am concerned with communication protocols, specially security protocols. Their design demand specialized tools, that will provide interactive simulations and security testing. I have described each of these tools in detail and mentioned about their properties, their pros and cons. In available tools I have implemented security protocols. The result is set of demonstration tasks that are usable in network courses at FIT VUT
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