|
|
"And yet the cruel fate hit me?" Widowed Prague bourgeois women in the second half of the 19th century in the reflection of ego-documents
MAREŠOVÁ, Dana
The dissertation presents the fate of widowed bourgeois women living in Prague during the second half of the 19th century on the basis of selected ego-documents and other sources. This thesis first focuses on women's lives before becoming widows and then captures the whole process of becoming a widow from the husband's death to the funeral and the first moments after his death. The thesis also considers the legal aspect of widowhood and the economic aspects connected with it, such as material security, job possibilities for widows, aid requests, widow´s association and accommodation possibilities. Other chapters deal with the everyday life of widowed women, networks of relationships, reflection and self-reflection of widowhood, experiencing of sadness and seeking solace from God. The core of the thesis is concluded by remembering the deceased husband, the last days, death and the "afterlife" of the widows. To complete the dissertation, the thesis is enriched by tables, appendices with depictions of relatives of widows, pictorial part, editorial processing of selected sources of personal nature and index of persons.
|
|
| |
|
|
název v anglickém jazyce není uveden
Kaiser, Miroslav ; Šťastný, František (advisor) ; Marešová, Dana (referee) ; Kršiak, Miloslav (referee)
Although the cause of schizophrenia is not fully elucidated, there is increasing evidence that this severe psychiatric illness may result from a disturbance early in development. Evidence for this so called "neuro- developmental hypothesis" comes from a variety of sources, including epidemiological, gynecological, psychological and pathological data. Fetal and perinatal hypoxia-ischemia belongs to obstetric complications which can increase the risk of schizophrenia. These complications such as premature rupture of fetal membranes, low birth weight, newborn immaturity, forceps delivery and resuscitation at birth are frequently accompanied by hypoxic-ischemic brain damage during delivery. We assume that perinatal hypoxia together with genetic factors influence a susceptibility to schizophrenia and represent significant risk factors of this disease. We used a heuristic model in our study to determine if brain hypoxic-ischemic episode can actually cause not only changes of biochemical markers but also behavioral changes resembling those seen in schizophrenia. Neurodevelopmental processes in neonatal rats continue during the first three weeks of postnatal life and reach the level of those observed in human newborns at the end of the second postnatal week. Therefore, rat pups at postnatal day 12 (PND12) were used...
|
|
|
Insulin secretion in women with polycystic ovary syndrome
Grimmichová, Tereza ; Haluzík, Martin (advisor) ; Marešová, Dana (referee) ; Rešlová, Taťána (referee)
Polycystic ovary syndrome (PCOS) is one of the most common endocrinopathies occuring in 5-10% women in their fertile years. The incidence of impaired glucose tolerance and diabetes mellitus type 2 is significantly increased in PCOS. Hyperinsulinaemia and insulin resistance are present in a relevant number of PCOS women. In our projects we therefore concentrated on various aspects of insulin secretion in PCOS women. We used different approaches and calculations, which are complementary to each other and provide a more detailed insight into possible beta cell dysfunction. Aims of our studies were 1) examine how the beta cell function is influenced by the family history of DM 2, 2) examine the insulin pulsatile secretion, 3) examine the secretion of incretins and 4) examine the prevalence of glucose intolerance and its potential prediction in PCOS women. 1) Decreased insulin sensitivity was observed only in PCOS women with the positive family history of DM 2 in comparison to healthy controls. If these women have normal glucose tolerance, they compensate the decreased insulin sensititivity by the increased insulin secretion. 2) Lean PCOS women had similar insulin pulsatile secretion patterns with the exception of broader insulin peaks in comparison to healthy controls. Insulin sensitivity was not associated...
|
|
|
Ultrasound imaging of posterior vaginal wall descent
Krčmář, Michal ; Marešová, Dana (advisor) ; Zmrhal, Jan (referee) ; Kittnar, Otomar (referee)
The aim of our study was to set up the parameters, which could be used in the future for objective assesment of posterior vaginal wall descent same as they have been used in the assesment of anterior compartment. We included 42 attendants, 21 with proven descent of posterior vaginal wall; 21 as a control group. We observed the ultrasonographical distance between the most descending point at posterior vaginal wall according to the horizontal line and the inferior margin of pubic bone same as posterior anorectal angle after the intrarectal application of sonographic yelly; both at rest and during Valsalva manévre. Doubleoptional t-test was used for statistical evaluation of the results. Furthermore we judged the demographic features of both groups. We proved the statistic significant decrease in measured distances in the group of patients suffering from the descent compared to the group of healthy women. Values of posterior anorectal angle were significantly highered in the group of patients with the descent. The incidence of descent is related to higher age, higher level of BMI and multiparity in the group of patients. There was also higher incidence of stress urinary incontinence in patients' group, which had been surgically treated. We obtained no explicit data about influence of menopausal status being an...
|
|
|
Coffee, tea and chocolate as a part of the life of noblemen during the early-modern times period in the Czech countries
MAREŠOVÁ, Dana
The thesis is entitled Coffee, tea and chocolate as a part of the life of noblemen during the early-modern times period in the Czech countries and it presents the history of everydayness of the nobility in the Czech Kingdom and in the Margraviate of Moravia from the middle of the 17th up to the ending of the 18th century, and it emphasizes the material culture which was used for drinking coffee, tea and chocolate. Castle inventories and municipal palaces inventories were used as an initial source of information. At the very beginning the noble families were chosen and afterwards their residential network was approached in detail. This work also focused on the topography of the residences and on the location of items used for coffee, tea and chocolate consumption within the particular castles or palaces. On this basis the author tried to reconstruct the way of thinking, behavior and attitudes of noblemen, and to explain the symbolic meaning of the decoration of the residences, the symbolic role of items as a representation of noblemen as a mean of the enrichment of their social and cultural habits as well. The set-up of items and other accessories served with coffee, tea and chocolate were not forgotten either. The inventories were put through a deep research which helped to create a social and power stratification on the basis of items used for coffee, tea and chocolate consumption. Another comparison also emerged- the comparison of particular members of various families representation and also the ownership of examined items on the basis of gender definition. This work tried to immerse to the topic of symbolic communication.
|
|
|
The endocrine function of adipose tissue and its importance for initiation and development of insulin resistance and diabetes
Haluzík, Michal ; Schreiber, Vratislav (advisor) ; Marešová, Dana (referee) ; Šeda, Ondřej (referee)
Endocrine production of adipose tissue is a very complex process affected by numerous endogenous and exogenous stimuli. Peroxisome proliferator-activated receptors-alpha (PPAR-) are important modulators of metabolic processes which can also affect endocrine function of adipose tissue. Recently, numerous novel factors produced by adipose tissue with important metabolic effects were identified. Some of them can directly bind PPAR receptors. One of the examples of these factors is fatty acid binding protein 4 (FABP4) which can directly bind PPAR receptors and indirectly modify its activation by changing availability of endogenous PPAR ligands -free fatty acids. We hypothesized that the mechanism of action of PPAR receptors to metabolic processes may partially lie in their complex interaction with adipose tissue-derived hormones. The unraveling of these interactions may have important consequences in finding approaches to treat patients with type 2 diabetes mellitus. (...) In summary, our data show an important role for the interplay of PPAR activation and endocrine function of adipose tissue in metabolic regulations which may have important clinical consequences.
|
|
|
Ultrasound imaging of posterior vaginal wall descent
Krčmář, Michal ; Marešová, Dana (advisor) ; Zmrhal, Jan (referee) ; Kittnar, Otomar (referee)
The aim of our study was to set up the parameters, which could be used in the future for objective assesment of posterior vaginal wall descent same as they have been used in the assesment of anterior compartment. We included 42 attendants, 21 with proven descent of posterior vaginal wall; 21 as a control group. We observed the ultrasonographical distance between the most descending point at posterior vaginal wall according to the horizontal line and the inferior margin of pubic bone same as posterior anorectal angle after the intrarectal application of sonographic yelly; both at rest and during Valsalva manévre. Doubleoptional t-test was used for statistical evaluation of the results. Furthermore we judged the demographic features of both groups. We proved the statistic significant decrease in measured distances in the group of patients suffering from the descent compared to the group of healthy women. Values of posterior anorectal angle were significantly highered in the group of patients with the descent. The incidence of descent is related to higher age, higher level of BMI and multiparity in the group of patients. There was also higher incidence of stress urinary incontinence in patients' group, which had been surgically treated. We obtained no explicit data about influence of menopausal status being an...
|
|
|
název v anglickém jazyce není uveden
Kaiser, Miroslav ; Šťastný, František (advisor) ; Marešová, Dana (referee) ; Kršiak, Miloslav (referee)
Although the cause of schizophrenia is not fully elucidated, there is increasing evidence that this severe psychiatric illness may result from a disturbance early in development. Evidence for this so called "neuro- developmental hypothesis" comes from a variety of sources, including epidemiological, gynecological, psychological and pathological data. Fetal and perinatal hypoxia-ischemia belongs to obstetric complications which can increase the risk of schizophrenia. These complications such as premature rupture of fetal membranes, low birth weight, newborn immaturity, forceps delivery and resuscitation at birth are frequently accompanied by hypoxic-ischemic brain damage during delivery. We assume that perinatal hypoxia together with genetic factors influence a susceptibility to schizophrenia and represent significant risk factors of this disease. We used a heuristic model in our study to determine if brain hypoxic-ischemic episode can actually cause not only changes of biochemical markers but also behavioral changes resembling those seen in schizophrenia. Neurodevelopmental processes in neonatal rats continue during the first three weeks of postnatal life and reach the level of those observed in human newborns at the end of the second postnatal week. Therefore, rat pups at postnatal day 12 (PND12) were used...
|
|
| |
guest ::
RSS feed.