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National Repository of Grey Literature 32 records found  beginprevious30 - 32  jump to record: Search took 0.01 seconds. 
Efektivní syntézy acyklických nukleosidfosfonátů s jedním otevřeným a jedním nově uzavřeným kruhem
 Jansa, Petr ; Dračínský, Martin ; Holý, Antonín
In order to study the SAR, we prepared new 6-[2-(phosphonomethoxy)ethoxy]-2,4-diaminopyrimidine (PMEO-DAPy) analogues substituted by another ring between positions 4 and 5.
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Příprava N9-(3-fluoro-2-phosphonomethoxypropyl) (FPMP) derivátů N6-substituovaných adeninů a 2,6-diaminopurinů
 Baszczyňski, Ondřej ; Holý, Antonín ; Dračínský, Martin ; Klepetářová, Blanka
An efficient method of the synthesis N9-(3-fluoro-2-phosphonomethoxypropyl) (FPMP) derivatives of purine bases was developed. A series of N6-substituted FPMP dervatives of purine and 2-aminopurine were prepared by using this method.
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Metalace 6-halo-2,4-dimethoxypyrimidinů jako klíčový krok pro syntézu biologicky aktivních sloučenin
 Nencka, Radim ; Hřebabecký, Hubert ; Votruba, Ivan ; Dračínský, Martin ; Holý, Antonín
Introduction of carbon substituents to the position C-5 and C-6 of uracil ring was performed by reaction of organometallic derivatives of uracil with electrophiles or by transition metal catalyzed cross-coupling reaction. Especially lithiathion was studied intensively.
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